Biological cell processing chip

Information

  • Patent Grant
  • D1016324
  • Patent Number
    D1,016,324
  • Date Filed
    Wednesday, October 20, 2021
    3 years ago
  • Date Issued
    Tuesday, February 27, 2024
    a year ago
  • Inventors
  • Original Assignees
    • NanoCav, LLC (Culver City, CA, US)
  • Examiners
    • Agilee; Omeed
    Agents
    • Harness Dickey & Pierce P.L.C.
  • US Classifications
    Field of Search
    • US
    • D24 168
    • D24 169
    • D24 186
    • D24 187
    • D24 200
    • D24 216
    • D24 223-227
    • D24 230
    • D24 232
    • D24 233
    • D10 81
    • CPC
    • A61B5/0002
    • A61B5/042
    • A61B5/0404
    • A61B5/0416
    • C40B40/06
    • B01L3/00
    • B01L3/502715
  • International Classifications
    • 2402
    • Term of Grant
      15Years
Abstract
Description


FIG. 1 is an isometric view of a biological cell processing chip in accordance with our new design;



FIG. 2 is a front elevation view thereof;



FIG. 3 is a rear elevation view thereof;



FIG. 4 is a right side elevation view thereof;



FIG. 5 is a left side elevation view thereof;



FIG. 6 is a top plan view thereof;



FIG. 7 is a bottom plan view thereof;



FIG. 8 is an isometric view of the biological cell processing chip of FIGS. 1-7 in a state of use;



FIG. 9 is an isometric view of another embodiment of a biological cell processing chip in accordance with our new design;



FIG. 10 is a front elevation view thereof;



FIG. 11 is a rear elevation view thereof;



FIG. 12 is a right side elevation view thereof;



FIG. 13 is a left side elevation view thereof;



FIG. 14 is a top plan view thereof;



FIG. 15 is a bottom plan view thereof; and,



FIG. 16 is an isometric view of the biological cell processing chip of FIGS. 9-15 in a state of use.


The broken lines in FIGS. 1-7 and 9-15, the areas within them, and the unshaded areas bounded by broken lines and solid lines depict portions of the biological cell processing chip that form no part of the claimed design. The additional broken lines shown in FIGS. 8 and 16 depict environmental subject matter and form no part of the claimed design.


Claims
  • The ornamental design for a biological cell processing chip, as shown and described.
US Referenced Citations (26)
Number Name Date Kind
5955028 Chow Sep 1999 A
6074605 Meserol et al. Jun 2000 A
6969604 Yakovenko Nov 2005 B1
D621060 Handique Aug 2010 S
D669191 Handique Oct 2012 S
D879999 Wronko Mar 2020 S
11046976 Wu Jun 2021 B2
20040197883 Dzekunov et al. Oct 2004 A1
20050118705 Rabbitt et al. Jun 2005 A1
20060057245 Haupt Mar 2006 A1
20090166201 Tian Jul 2009 A1
20100216126 Balachandran Aug 2010 A1
20130256132 Chen Oct 2013 A1
20140332377 Su Nov 2014 A1
20170010259 Amoabediny Jan 2017 A1
20170037357 Cattaruzzi et al. Feb 2017 A1
20170240945 Marquant Aug 2017 A1
20170283761 Corso Oct 2017 A1
20190136224 Garcia Dominguez et al. May 2019 A1
20200017847 Chang Jan 2020 A1
20200221987 Liu Jul 2020 A1
20200238282 Burns Jul 2020 A1
20200249232 Konstantopoulos Aug 2020 A1
20200340014 Chang Oct 2020 A1
20220025402 Chang et al. Jan 2022 A1
20220088604 Yu Mar 2022 A1
Foreign Referenced Citations (8)
Number Date Country
101928666 Apr 2013 CN
103451097 Dec 2013 CN
106995783 Aug 2017 CN
208250332 Dec 2018 CN
D2019-7688 Feb 2020 JP
WO-2006112870 Oct 2006 WO
WO-2020014264 Jan 2020 WO
WO-2021007315 Jan 2021 WO
Non-Patent Literature Citations (26)
Entry
How microfluidics can automate drug discovery and development. Online, published day May 17, 2021. Retrieved on Sep. 11, 2022 from URL: https://www.drugtargetreview.com/article/91542/how-microfluidics-can-automate-drug-discovery-and-development/.
Book Chapter on Design and Fabrication of Microfluidic Devices Published. Online, published date Aug. 26, 2021. Retrieved on May 20, 2023 from URL: https://people.sutd.edu.sg/˜hashimoto/book-chapter-on-design-and-fabrication-of-microfluidic-devices-published/.
High flow rate microfluidic device for blood plasma separation using a range of temperatures. Online, published date 2010. Retrieved on May 20, 2023 from URL: https://pubs.rsc.org/en/content/articlelanding/2010/lc/b904531g.
Andresen et al., “Injection molded chips with integrated conducting polymer electrodes for electroporation of cells,” Journal of Micromechanics and Microengineering, 20: 1-9 (2010).
Boissel, L., et al., “Transfection with mRNA for CD19 specific chimeric antigen receptor restores NK cell mediated killing of CLL cells,” Leuk Res., 33(9): 1255-1259 (2009).
Choi et al., “A high throughput microeletroporatin device to introduce a chimeric antigen receptor to redirect the specificity of human T cells,” Biomed Microdevices, 12: 855-863 (2010).
Ding et al., “High-throught neclear delivery and repid expression of DNA via mechanical and electrical cell-membrane disruption,” Nature biomedical engineering, 1(39): 1-7 (2017).
Examination Report from corresponding Australian Application No. 2020311908 dated Feb. 10, 2022.
International Preliminary Report on Patentability from PCT Application No. PCT/US2019/041055 dated Sep. 15, 2020.
International Search Report from corresponding PCT Application No. PCT/US2020/041188 dated Oct. 21, 2020.
International Search Report from PCT Application No. PCT/US2019/041055 dated Sep. 23, 2019.
Jiang, W., et al., “Functional characterization of interleukin-15 gene transduction into the human natural killer cell line NKL,” Cytotherapy, 10(3): 265-274 (2008).
Li, S., “Electroporation Protocols: Preclinical and clinical gene medicine,” Shulin Li (Ed.), Methods in Molecular Biology, 423: 1-511 (2008).
MaxCyte, “ExPERT GTx,” (2020).
MaxCyte, “EXPERT STx,” (2020).
MaxCyte, “MaxCyte VLX® Large-Scale Transfection System,” (2017).
Moffett, H.F., et al., “Hit-and-run programming of therapeutic cytoreagents using mRNA nanocarriers,” Nature Communications, 8(389): 1-13 (2017).
Office Action from corresponding Japanese Application No. 2021-501021 dated Apr. 5, 2022.
Office Action from corresponding U.S. Appl. No. 16/506,190 dated Sep. 16, 2021.
Selmeczi et al., “Efficient large volume electroporation of dendritic cells through micrometer scale manipulation of flow in a disposable polymer chip,” Biomed Microdevices, 13: 383-392 (2011).
Selmeczi et al., “Large scale mRNA Transfection of Dendritic Cells by Electroporation in Ccontinuous Flow Systems,” Methods in Molecular Biology, 1428 (Chapter 10) :151-161 (2016).
Wei, Z., et al., “A Laminar Flow Electroporation System for Efficient DNA and siRNA Delivery,” Analytical Chemistry, 83: 5881-5887 (2011).
Written Opinion from corresponding PCT Application No. PCT/US2020/041188 dated Oct. 21, 2020.
Written Opinion from PCT Application No. PCT/US2019/041055 dated Sep. 23, 2019.
Young, J.L. & Dean, D.A., “Electroporation-Mediated Gene Delivery,” Adv. Genet, 89: 49-88 (2015).
Zhao, D., et al., “A Flow-Through Cell Electroporation Device for Rapidly and Efficiently Transfecting Massive Amounts of Cells in vitro and ex vivo , ” Scientific Reports, 6: 1-9 (2016).
Continuation in Parts (1)
Number Date Country
Parent 16923606 Jul 2020 US
Child 29812292 US