DEEPHIPPO: Ultra-thin lensless endoscope for the visualization of deep hippocampus neuronal functional activity.

Information

  • Research Project
  • 9776522
  • ApplicationId
    9776522
  • Core Project Number
    R21EY029406
  • Full Project Number
    5R21EY029406-02
  • Serial Number
    029406
  • FOA Number
    RFA-EY-17-002
  • Sub Project Id
  • Project Start Date
    9/30/2018 - 6 years ago
  • Project End Date
    8/31/2020 - 4 years ago
  • Program Officer Name
    FLANDERS, MARTHA C
  • Budget Start Date
    9/1/2019 - 5 years ago
  • Budget End Date
    8/31/2020 - 4 years ago
  • Fiscal Year
    2019
  • Support Year
    02
  • Suffix
  • Award Notice Date
    8/9/2019 - 5 years ago

DEEPHIPPO: Ultra-thin lensless endoscope for the visualization of deep hippocampus neuronal functional activity.

Rigneault Project Abstract DEEPHIPPO DEEPHIPPO: Ultra?thin lensless endoscope for the visualization of deep hippocampus neuronal functional activity. Principal investigator: Hervé Rigneault Host Institution: Aix?Marseille University, Marseille, France Project duration : 24 months Project Abstract DEEPHIPPO breaks the experimental limitations of in vivo two?photon calcium imaging in the deep brain where multiphoton (2photon and 3photon) microscopy is impossible. Using innovative multicore optical fibers together with wavefront shaping DEEPHIPPO aims at developing a novel and disruptive 2photon endoscope technology featuring a distal diameter as small as the fiber diameter. The technology will be validated to record neural activity either in CA1 or CA3 in freely moving mice. Addressing this timely biological question provides the drive for a tool development that will obviously pave the way to image deep brain structures in behaving animal models. 1

IC Name
NATIONAL EYE INSTITUTE
  • Activity
    R21
  • Administering IC
    EY
  • Application Type
    5
  • Direct Cost Amount
    120000
  • Indirect Cost Amount
    9600
  • Total Cost
    129600
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    867
  • Ed Inst. Type
  • Funding ICs
    NEI:129600\
  • Funding Mechanism
    Non-SBIR/STTR RPGs
  • Study Section
    ZEY1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    AIX-MARSEILLE UNIVERSITY
  • Organization Department
  • Organization DUNS
    263492950
  • Organization City
    MARSEILLE
  • Organization State
  • Organization Country
    FRANCE
  • Organization Zip Code
    13284
  • Organization District
    FRANCE