FLUORESCENT INDICATOR DYES FOR EXTRACELLULAR IONS

Information

  • Research Project
  • 6159249
  • ApplicationId
    6159249
  • Core Project Number
    N43HC095174
  • Full Project Number
    N43HC095174-001
  • Serial Number
    95174
  • FOA Number
  • Sub Project Id
  • Project Start Date
    8/1/1999 - 25 years ago
  • Project End Date
    1/31/2000 - 24 years ago
  • Program Officer Name
  • Budget Start Date
    8/24/1999 - 25 years ago
  • Budget End Date
    1/31/2000 - 24 years ago
  • Fiscal Year
    1999
  • Support Year
  • Suffix
  • Award Notice Date
    -
Organizations

FLUORESCENT INDICATOR DYES FOR EXTRACELLULAR IONS

To develop fluorescent indicator dyes for the utilization of optical methods to determine airway surface liquid and other fluid composition by measurement of the emission of fluorescent indicator dyes for Na or Cl covalently attached to a large dextran molecule or latex bead. The ion indicators must change their fluorescence emission or absorption in proportion to alterations in the Na or Cl concentration of extracellular fluids, concentrations of about 150 mM. The indicator dyes should be excited by visible wavelength light, be water soluble, non-toxic, and minimally affected by the presence of proteins.

IC Name
DIVISION OF EPIDEMIOLOGY AND CLINICAL APPLICATIONS
  • Activity
    N43
  • Administering IC
    HC
  • Application Type
    3
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
  • Ed Inst. Type
  • Funding ICs
  • Funding Mechanism
  • Study Section
  • Study Section Name
  • Organization Name
    HELIX RESEARCH COMPANY
  • Organization Department
  • Organization DUNS
  • Organization City
    GOSHEN
  • Organization State
    OR
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    97405
  • Organization District
    UNITED STATES