Method and formulations to concurrently reduce fracture risk and insure appropriate fat-soluble vitamin supplementation when using Orlistat, an oral lipase inhibitor

Abstract

Orlistat is an oral lipase inhibitor that blocks the absorption of ingested fats from the small intestines, to enable proven weight loss. Fat-soluble vitamin deficiencies can be a consequence of orlistat use, especially if used for a long time without medical supervision. The present invention comprises a fat-soluble-only vitamin complex, specifically for use with orlistat, which vitamin complex contains a significantly increased amount of vitamin D, to prevent osteoporosis and to reduce fracture risk.

Description

DESCRIPTION OF THE PRESENT INVENTION

The invention comprises a fat-soluble-only vitamin complex containing vitamin A, D, E, K, and beta carotene, without water soluble vitamins, to be orally ingested during Orlistat therapy for weight loss. The fat-soluble vitamin complex will be ingested two hours before or two hours after Orlistat dosing as is currently recommended for a multivitamin with water-soluble vitamins included. In addition, the vitamin D component of the fat-soluble-only vitamin complex, would reflect a dosage of vitamin D that the recent medical literature has documented to prevent vitamin D inadequacy/insufficiency, osteoporosis risks and fracture risks.

Proposed fat-soluble vitamin complex
		% FDA recommended
Component		of daily need
Vitamin A	5000 IU	100%
41% as beta carotene
Prevents night blindness
Vitamin D	1000 IU to 1500 IU	250–375%
Prevents osteoporosis
Decreases fracture risks
Vitamin E	45 IU	150%
Anti-oxidant
Prevents premature
cell death
Vitamin K	80 micrograms	100%
Allows normal coagulation

The invention thus comprises a method of treating fat-soluble vitamin deficiencies in a being under Orlistat treatment therapy, comprising the steps of: ingesting a “fat-soluble-only” vitamin supplement during the period in which the orlistat treatment occurs. The “fat-soluble-vitamin” supplement comprises vitamins A, D, E, K and beta carotene. The “fat-soluble-only” vitamin supplement is preferably taken two hours before or after Orlistat ingestion.

The invention also comprises a “fat-soluble-only” vitamin complex for the treatment of vitamin D deficiency effected by ingestion of the lipase-inhibitor treatment Orlistat, including: between 1000 IU and 1500 IU o-f vitamin D, 5000 IU of vitamin A, 45 IU of vitamin E and 80 micrograms of vitamin K.

Claims

1. A method of treating fat-soluble vitamin deficiencies in a being under Orlistat treatment therapy, comprising: ingesting a “fat-soluble-only” vitamin supplement during the period in which the orlistat treatment occurs.

2. The method as recited in claim 1, wherein said “fat-soluble-vitamin” supplement comprises vitamins A, D, E, K and beta carotene.

3. The method as recited in claim 1, wherein said “fat-soluble-only” vitamin supplement is taken two hours before or after Orlistat ingestion.

4. A “fat-soluble-only” vitamin complex for the treatment of vitamin D deficiency effected by ingestion of the lipase-inhibitor treatment Orlistat, including: between 1000 IU and 1500 IU of vitamin D, 5000 IU of vitamin A and 45 IU of vitamin E, and 80 micrograms of vitamin K.