Pilot HGDP: Croos-Cultural Issues in Genetic Research with Plains Apaches: A Pilot Study for the Human Genome Diversity Project

Information

• NSF Award
• 9610336

Owner

• University of Oklahoma Health Sciences Center

• Award Id

  9610336

• Award Effective Date

  4/15/1997 - 28 years ago

• Award Expiration Date

  3/31/2000 - 25 years ago

• Award Amount

  $ 110,000.00

• Award Instrument

  Standard Grant

This project focuses on ethical and legal issues for genetics research in an American Indian community. First, conditions for such research involving the Apache Tribe of Oklahoma will be negotiated with the tribal government. Negotiations will address the following issues: privacy, group stigmatization, publication of findings, property rights, and the disposition of samples. The response of individual tribal members to genetics research will be studied. Second, research will address susceptibility to diabetes and resistance to cancer. A mutation first found in Pima Indians may affect the function of adrenaline, contributing risk for diabetes. In addition, a genetic variant in the male hormone system may offer protection from prostate cancer. The role of these factors in the health of this population will be tested, following guidelines negotiated with the tribe. Prevention of diseases such as diabetes and cancer needs improvement. Relevant discoveries can arise from studying why health patterns vary in different populations. To achieve this goal of the Human Diversity Genome Project, it is crucial to satisfy ethical concerns about research from different cultural perspectives. This pilot study will explore how genetics researchers and indigenous communities can collaborate.

• Program Officer

  Mark L. Weiss

• Min Amd Letter Date

  3/27/1997 - 28 years ago

• Max Amd Letter Date

  6/30/1998 - 27 years ago

• ARRA Amount

• Name

  University of Oklahoma Health Sciences Center

• City

  Oklahoma City

• State

  OK

• Country

  United States

• Address

  865 Research Parkway

• Postal Code

  731043609

• Phone Number

  4052712090

• First Name

  Morris

• Last Name

  Foster

• Start Date

  3/27/1997 12:00:00 AM

• First Name

  Thomas

• Last Name

  Carter

• Email Address

  Tom-Carter@uokhsc.edu

• Start Date

  3/27/1997 12:00:00 AM

• Name

  Other Applications NEC

• Code

  99

• Name

  Human Subjects

• Code

  116000

• Text

  Biological Anthropology

• Code

  1392

• Text

  POPULATION DYNAMICS

• Code

  1174

• Text

  UNASSIGNED

• Code

  0

• Text

  OTHER RESEARCH OR EDUCATION