Claims
- 1. A process for producing N,N'-methylene-2,2'-azapyridocyanines represented by the formulas ##STR4## or the halide quaternary salts thereof, which comprises reacting a compound represented by the formulas ##STR5## wherein R is hydrogen or lower alkyl, with the proviso that R at the 6-position of the aminopyridine must be hydrogen, with a methylene halide represented by the formula CH.sub.2 X.sub.2 wherein X is halogen, under reflux in the presence of a dry, inert organic solvent for a time sufficient to complete the reaction.
- 2. The process of claim 1 wherein X is iodine and the solvent is acetonitrile.
- 3. The process of claim 2 wherein the reactants are 2-aminopyridine and methyl iodide and the product is N,N'-methylene-2,2'-azapyridocyanine.
- 4. The process of claim 2 wherein the reactants are 2-amino-3-picoline and methylene iodide and the product is N,N'-methylene-3,3'-dimethyl-2,2'-azapyridocyanine.
- 5. The process of claim 2 wherein the reactants are 2-amino-4-picoline and methylene iodide and the product is N,N'-methylene-4,4'-dimethyl-2,2'-azapyridocyanine.
- 6. The process of claim 2 wherein the reactants are 2-amino-5-picoline and methylene iodide and the product is N,N'-methylene-5,5'-dimethyl-2,2'-azapyridocyanine.
- 7. The process of claim 2 wherein the reactants are 4-aminopyrimidine and methylene iodide and the product is N,N'-methylene-5,5'-diaza-2,2'-azapyridocyanine.
GOVERNMENT RIGHTS
The invention described herein may be manufactured, used and licensed by the Government for Governmental purposes without the payment to us of any royalties thereon.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
3056751 |
Fierce et al. |
Oct 1962 |
|
Non-Patent Literature Citations (2)
Entry |
Leubner, J. Org. Chem., vol. 38, 1098 (1973). |
Leubner et al., Chemical Abstracts, vol. 70, entry 42494q (1969). |