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1,4-Benzodiazepines Hydrogenated 1,4-benzodiazepines
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C07D243/14
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HETEROCYCLIC COMPOUNDS
C07D243/00
Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
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1,4-Benzodiazepines Hydrogenated 1,4-benzodiazepines
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last 30 patents
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Patent Grant
Inhibitors of EGFR and methods of use thereof
Patent number
12,161,649
Issue date
Dec 10, 2024
Dana-Farber Cancer Institute, Inc.
Nathanael S. Gray
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bicyclic 1,4-diazepanones and therapeutic uses thereof
Patent number
11,981,644
Issue date
May 14, 2024
Cytokinetics, Inc.
Bradley P. Morgan
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compounds for the treatment of Alzheimer's disease
Patent number
11,939,302
Issue date
Mar 26, 2024
The Governors of the University of Alberta
James A. Nieman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
3-alkyl-4-amido-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
11,891,365
Issue date
Feb 6, 2024
Valo Health, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Metabotropic glutamate receptor negative allosteric modulators (NAM...
Patent number
11,447,453
Issue date
Sep 20, 2022
Sanford Burnham Prebys Medical Discovery Institute
Nicholas David Peter Cosford
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Alcoxyamino derivatives for treating pain and pain related conditions
Patent number
11,401,270
Issue date
Aug 2, 2022
ESTEVE PHARMACEUTICALS, S.A.
Carmen Almansa-Rosales
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-alkyl bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
11,279,681
Issue date
Mar 22, 2022
Valo Health, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
11,274,084
Issue date
Mar 15, 2022
Valo Health, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-aryl-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
11,274,085
Issue date
Mar 15, 2022
Valo Health, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Therapeutic compounds and uses thereof
Patent number
11,168,070
Issue date
Nov 9, 2021
Genentech, Inc.
Patrick Cyr
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Synthesis of trans-8-chloro-5-methyl-1-[4-(pyridin-2-yloxy)-cyclohe...
Patent number
11,040,977
Issue date
Jun 22, 2021
HOFFMANN-LA ROCHE INC.
Benno Rothenhaeusler
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-alkyl-4-amido-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
10,988,450
Issue date
Apr 27, 2021
Valo Early Discovery, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Inhibitors of KRAS G12C mutant proteins
Patent number
10,975,071
Issue date
Apr 13, 2021
ARAXES PHARMA LLC
Liansheng Li
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
10,829,461
Issue date
Nov 10, 2020
Valo Early Discovery, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-alkyl bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
10,829,462
Issue date
Nov 10, 2020
Valo Early Discovery, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-aryl-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
10,822,316
Issue date
Nov 3, 2020
Valo Early Discovery, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Aryldiazepine derivatives as RSV inhibitors
Patent number
10,752,598
Issue date
Aug 25, 2020
Enanta Pharmaceuticals, Inc.
Yat Sun Or
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Therapeutic compounds and uses thereof
Patent number
10,696,655
Issue date
Jun 30, 2020
Genentech, Inc.
Patrick Cyr
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Clostridium difficile toxin inhibitors
Patent number
10,669,242
Issue date
Jun 2, 2020
Venenum Biodesign, LLC
Jeffrey J. Letourneau
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Metabotropic glutamate receptor negative allosteric modulators (NAM...
Patent number
10,597,367
Issue date
Mar 24, 2020
Sanford Burnham Prebys Medical Discovery Institute
Nicholas David Peter Cosford
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Pyrrolobenzodiazepines and conjugates thereof
Patent number
10,526,294
Issue date
Jan 7, 2020
Mersana Therapeutics, Inc.
Joshua D. Thomas
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
3-alkyl bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
10,513,501
Issue date
Dec 24, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-aryl-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
10,501,424
Issue date
Dec 10, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-aryl-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
10,494,351
Issue date
Dec 3, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-aryl-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
10,494,352
Issue date
Dec 3, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
10,494,353
Issue date
Dec 3, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-aryl-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
10,494,354
Issue date
Dec 3, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
10,479,772
Issue date
Nov 19, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
10,472,337
Issue date
Nov 12, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-alkyl-4-amido-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
Patent number
10,464,909
Issue date
Nov 5, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Patents Applications
last 30 patents
Information
Patent Application
Compounds for the Treatment of Alzheimer's Disease
Publication number
20240376059
Publication date
Nov 14, 2024
The Governors of the University of Alberta
James A. Nieman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BICYCLIC 1,4-DIAZEPANONES AND THERAPEUTIC USES THEREOF
Publication number
20240368091
Publication date
Nov 7, 2024
Cytokinetics, Inc.
Bradley P. MORGAN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
POTASSIUM CHANNEL MODULATOR, COMPOSITION AND APPLICATION
Publication number
20240317689
Publication date
Sep 26, 2024
NEUSHEN THERAPEUTICS (SHANGHAI) CO., LTD
Miao HU
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
DEUTERATED 1,4-BENZODIAZEPINE-2,5-DIONE COMPOUND AND USE THEREOF
Publication number
20240002353
Publication date
Jan 4, 2024
NINGBO COMBIREG PHARMACEUTICAL TECHNOLOGY CO., LTD.
Gang LIU
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METABOTROPIC GLUTAMATE RECEPTOR NEGATIVE ALLOSTERIC MODULATORS (NAM...
Publication number
20230113588
Publication date
Apr 13, 2023
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
Nicholas David Peter COSFORD
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BICYCLIC 1,4-DIAZEPANONES AND THERAPEUTIC USES THEREOF
Publication number
20230083960
Publication date
Mar 16, 2023
Cytokinetics, Inc.
Bradley P. MORGAN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ALKYL-4-AMIDO-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20220363651
Publication date
Nov 17, 2022
Valo Early Discovery, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ARYL-4-AMIDO-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20220204461
Publication date
Jun 30, 2022
Valo Health, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Compounds for the Treatment of Alzheimer's Disease
Publication number
20220119356
Publication date
Apr 21, 2022
The Governors of the University of Alberta
James A. Nieman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
INHIBITORS OF EGFR AND METHODS OF USE THEREOF
Publication number
20210346395
Publication date
Nov 11, 2021
Dana-Farber Cancer Institute, Inc.
NATHANAEL S. GRAY
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SYNTHESIS OF TRANS-8-CHLORO-5-METHYL-1 -[4-(PYRIDIN-2-YLOXY)-CYCLOH...
Publication number
20210284648
Publication date
Sep 16, 2021
HOFFMANN-LA ROCHE INC.
Benno Rothenhaeusler
C07 - ORGANIC CHEMISTRY
Information
Patent Application
COMBINATION COMPOSITIONS COMPRISING BISFLUOROALKYL-1,4- BENZODIAZEP...
Publication number
20210040050
Publication date
Feb 11, 2021
Ayala Pharmaceuticals Inc.
Matti Davis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
3-ALKYL BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20210009539
Publication date
Jan 14, 2021
Valo Early Discovery, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ARYL-4-AMIDO-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20210009538
Publication date
Jan 14, 2021
Valo Early Discovery, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ARYL-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20210009540
Publication date
Jan 14, 2021
Valo Early Discovery, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
THERAPEUTIC COMPOUNDS AND USES THEREOF
Publication number
20200399244
Publication date
Dec 24, 2020
Genentech, Inc.
Patrick Cyr
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METABOTROPIC GLUTAMATE RECEPTOR NEGATIVE ALLOSTERIC MODULATORS (NAM...
Publication number
20200347021
Publication date
Nov 5, 2020
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
Nicholas David Peter COSFORD
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
NEW ALCOXYAMINO DERIVATIVES FOR TREATING PAIN AND PAIN RELATED COND...
Publication number
20200299297
Publication date
Sep 24, 2020
ESTEVE PHARMACEUTICALS, S.A.
Carmen ALMANSA-ROSALES
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ALKYL BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20200055830
Publication date
Feb 20, 2020
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ARYL-4-AMIDO-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20200048211
Publication date
Feb 13, 2020
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ARYL-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20200048212
Publication date
Feb 13, 2020
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ALKYL-4-AMIDO-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20200002298
Publication date
Jan 2, 2020
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SYNTHESIS OF TRANS-8-CHLORO-5-METHYL-1 -[4-(PYRIDIN-2-YLOXY)-CYCLOH...
Publication number
20190194210
Publication date
Jun 27, 2019
HOFFMANN-LA ROCHE INC.
Benno Rothenhaeusler
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ALKYL-4-AMIDO-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20190127339
Publication date
May 2, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ARYL-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20190119235
Publication date
Apr 25, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ALKYL-4-AMIDO-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20190119227
Publication date
Apr 25, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ALKYL-4-AMIDO-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20190119230
Publication date
Apr 25, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ARYL-4-AMIDO-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20190119231
Publication date
Apr 25, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ARYL-4-AMIDO-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20190119233
Publication date
Apr 25, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY
Information
Patent Application
3-ARYL-4-AMIDO-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS
Publication number
20190119234
Publication date
Apr 25, 2019
Forma Therapeutics, Inc.
Xiaozhang Zheng
C07 - ORGANIC CHEMISTRY