Animal expressing industrially exogenous proteins

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A01K2267/01

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AHUMAN NECESSITIES A01Agriculture A01KANIMAL HUSBANDRY CARE OF BIRDS, FISHES, INSECTS FISHING REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR NEW BREEDS OF ANIMALS A01K2267/00Animals characterised by purpose

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A01K2267/01Animal expressing industrially exogenous proteins

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Patents Grantslast 30 patents

Information Patent Grant
Transgenic rainbow shark
- Patent number 12,225,888
- Issue date Feb 18, 2025
- GloFish, LLC
- Alan Blake
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
ADAM6 mice
- Patent number 12,207,628
- Issue date Jan 28, 2025
- REGENERON PHARMACEUTICALS, INC.
- Lynn Macdonald
- B60 - VEHICLES IN GENERAL
Information Patent Grant
Method of treating rheumatoid arthritis using antibodies to oxidize...
- Patent number 12,209,119
- Issue date Jan 28, 2025
- The Regents of the University of California
- Joseph L. Witztum
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Non-human animals having a humanized signal-regulatory protein gene
- Patent number 12,161,097
- Issue date Dec 10, 2024
- REGENERON PHARMACEUTICALS, INC.
- Andrew J. Murphy
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Camelization of a human variable domain by gene conversion
- Patent number 12,102,070
- Issue date Oct 1, 2024
- Crystal Bioscience Inc.
- William Don Harriman
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Transgenic animals and methods of use
- Patent number 12,096,753
- Issue date Sep 24, 2024
- Matthias Wabl
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Non-human animals having a humanized lymphocyte-activation gene 3
- Patent number 12,096,754
- Issue date Sep 24, 2024
- REGENERON PHARMACEUTICALS, INC.
- Alexander O. Mujica
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Human antibody-producing non-human animal and method for preparing...
- Patent number 12,063,913
- Issue date Aug 20, 2024
- National University Corporation Tottori University
- Yasuhiro Kazuki
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Transgenic mouse for aglycosylated antibody production and use of a...
- Patent number 12,048,296
- Issue date Jul 30, 2024
- Korea Research Institute of Bioscience & Biotechnology
- Yong Sam Kim
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Recombinant protein production system
- Patent number 12,018,287
- Issue date Jun 25, 2024
- Katholieke Universiteit Leuven
- Kim De Keersmaecker
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Human antibodies from transgenic rodents with multiple heavy chain...
- Patent number 12,016,313
- Issue date Jun 25, 2024
- OMNIAB OPERATIONS, INC.
- Roland Buelow
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Siglec transgenic mice and methods of use thereof
- Patent number 12,004,494
- Issue date Jun 11, 2024
- ALECTOR LLC
- Arnon Rosenthal
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Genetically modified non-human animals with humanized immunoglobuli...
- Patent number 12,004,495
- Issue date Jun 11, 2024
- Biocytogen Pharmaceuticals (Beijing) Co., Ltd
- Yuelei Shen
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Genetically modified non-human animals with common light chain immu...
- Patent number 11,997,994
- Issue date Jun 4, 2024
- Biocytogen Pharmaceuticals (Beijing) Co., Ltd
- Yabo Zhang
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Method for producing recombinant proteins in insects
- Patent number 11,991,994
- Issue date May 28, 2024
- Future Fields Cellular Agriculture and Research LTD.
- Matthew Anderson-Baron
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
High-throughput mouse model for optimizing antibody affinities
- Patent number 11,974,553
- Issue date May 7, 2024
- Children's Medical Center Corporation
- Frederick W. Alt
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Humanized IL-4 and IL-4Rα animals
- Patent number 11,963,521
- Issue date Apr 23, 2024
- REGENERON PHARMACEUTICALS, INC.
- Li-Hsien Wang
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
ADAM6 mice
- Patent number 11,950,578
- Issue date Apr 9, 2024
- REGENERON PHARMACEUTICALS, INC.
- Lynn Macdonald
- B60 - VEHICLES IN GENERAL
Information Patent Grant
Long germline DH genes and long HCDR3 antibodies
- Patent number 11,946,063
- Issue date Apr 2, 2024
- TRIANNI, INC.
- Matthias Wabl
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Non-human animals expressing humanized CD3 complex
- Patent number 11,937,587
- Issue date Mar 26, 2024
- REGENERON PHARMACEUTICALS, INC.
- Kara L. Olson
- G01 - MEASURING TESTING
Information Patent Grant
Antibody producing non-human animals
- Patent number 11,925,174
- Issue date Mar 12, 2024
- Merus N.V.
- Ton Logtenberg
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods, cells and organisms
- Patent number 11,920,128
- Issue date Mar 5, 2024
- Kymab Limited
- Allan Bradley
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Enhanced immunoglobulin diversity
- Patent number 11,889,821
- Issue date Feb 6, 2024
- TRIANNI, INC.
- Matthias Wabl
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antibody production
- Patent number 11,877,565
- Issue date Jan 23, 2024
- Erasmus University Medical Center
- Roger Kingdon Craig
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Genetically modified non-human animals and methods for producing he...
- Patent number 11,832,598
- Issue date Dec 5, 2023
- AKEAGEN, INC.
- Libin Cui
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Animal models and therapeutic molecules
- Patent number 11,812,731
- Issue date Nov 14, 2023
- Kymab Ltd.
- Allan Bradley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antibody producing non-human animals
- Patent number 11,785,924
- Issue date Oct 17, 2023
- Merus N.V.
- Ton Logtenberg
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Genetically modified non-human animals and methods of use thereof
- Patent number 11,778,995
- Issue date Oct 10, 2023
- REGENERON PHARMACEUTICALS, INC.
- Richard Flavell
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
High-throughput mouse model for optimizing antibody affinities
- Patent number 11,771,069
- Issue date Oct 3, 2023
- Children's Medical Center Corporation
- Frederick W. Alt
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Genetically modified non-human animals expressing human EPO
- Patent number 11,766,032
- Issue date Sep 26, 2023
- REGENERON PHARMACEUTICALS, INC.
- Andrew J. Murphy
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
TRANSGENIC PURPLE BETTA AND METHODS OF MAKING THE SAME
- Publication number 20250031678
- Publication date Jan 30, 2025
- GloFish, LLC
- Aidas NASEVICIUS
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
TRANSGENIC MICE WITH HUMANIZED MHC I AND IMMUNOGLOBLUIN HEAVY CHAIN...
- Publication number 20240425599
- Publication date Dec 26, 2024
- Regeneron Pharmaceuticals, Inc.
- Andrew J. Murphy
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
TRANSGENIC MICE WITH HUMANIZED MHC I AND IMMUNOGLOBLUIN HEAVY CHAIN...
- Publication number 20240425600
- Publication date Dec 26, 2024
- Regeneron Pharmaceuticals, Inc.
- Andrew J. Murphy
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
TRANSGENIC MAMMALS AND METHODS OF USE THEREOF
- Publication number 20240423175
- Publication date Dec 26, 2024
- TRIANNI, INC.
- Peter Burrows
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
NON-HUMAN ANIMALS HAVING A HUMANIZED LYMPHOCYTE-ACTIVATION GENE 3
- Publication number 20240397919
- Publication date Dec 5, 2024
- Regeneron Pharmaceuticals, Inc.
- Alexander O. Mujica
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MAMMALIAN ARTIFICIAL CHROMOSOME VECTOR HAVING HUMAN IMMUNOGLOBULIN...
- Publication number 20240392313
- Publication date Nov 28, 2024
- NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY
- Yasuhiro KAZUKI
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
HUMAN ANTIBODIES FROM TRANSGENIC RODENTS WITH MULTIPLE HEAVY CHAIN...
- Publication number 20240373832
- Publication date Nov 14, 2024
- OMNIAB OPERATIONS, INC.
- Roland BUELOW
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMALS WITH HUMANIZED IMMUNOGLOBULI...
- Publication number 20240373831
- Publication date Nov 14, 2024
- Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
- Yuelei Shen
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
TRANSGENIC TEAL TETRA
- Publication number 20240358006
- Publication date Oct 31, 2024
- Spectrum Brands, Inc.
- Aidas NASEVICIUS
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HUMAN LAMBDA LIGHT CHAIN MICE
- Publication number 20240327785
- Publication date Oct 3, 2024
- Regeneron Pharmaceuticals, Inc.
- Lynn Macdonald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED EASTERN EQUINE ENCEPHALITIS VIRUSES, SELF-REPLICATING RNA...
- Publication number 20240327865
- Publication date Oct 3, 2024
- Nathaniel Stephen WANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TRANSGENIC CORY
- Publication number 20240315218
- Publication date Sep 26, 2024
- GloFish, LLC
- Alan BLAKE
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
NUCLEIC ACIDS ENCODING ANCHOR MODIFIED ANTIBODIES AND USES THEREOF
- Publication number 20240317849
- Publication date Sep 26, 2024
- Regeneron Pharmaceuticals, Inc.
- Jason Mastaitis
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ADAM6 MICE
- Publication number 20240306617
- Publication date Sep 19, 2024
- Regeneron Pharmaceuticals, Inc.
- Lynn Macdonald
- B60 - VEHICLES IN GENERAL
Information Patent Application
Non-Human Animals Expressing Humanized CD3 Complex
- Publication number 20240306616
- Publication date Sep 19, 2024
- Regeneron Pharmaceuticals, Inc.
- Kara L. Olson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTI-CRISPR CONSTRUCT AND ITS USE TO COUNTERACT A CRISPR-BASED GENE...
- Publication number 20240292819
- Publication date Sep 5, 2024
- Imperial College Innovations Limited
- Chrysanthi Taxiarchi
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
TRANSGENIC CORY
- Publication number 20240284883
- Publication date Aug 29, 2024
- GloFish, LLC
- Alan BLAKE
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMALS WITH COMMON LIGHT CHAIN IMMU...
- Publication number 20240284885
- Publication date Aug 29, 2024
- Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
- Yabo Zhang
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
ANTIBODY PRODUCTION
- Publication number 20240276959
- Publication date Aug 22, 2024
- Erasmus University Medical Center Rotterdam
- Roger Kingdon Craig
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
METHOD FOR PREPARING TRANSGENIC NON-HUMAN ANIMAL HAVING GENOME INCL...
- Publication number 20240268360
- Publication date Aug 15, 2024
- Humab Co., Ltd.
- Chang Kyu OH
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHOD FOR PRODUCING RECOMBINANT PROTEINS IN INSECTS
- Publication number 20240268362
- Publication date Aug 15, 2024
- Future Fields Cellular Agriculture and Research LTD.
- Matthew Anderson-Baron
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
CHIMERIC TRANSGENIC IMMUNOGLOBULIN MICE WITH AN ALTERED HEAVY CHAIN...
- Publication number 20240260553
- Publication date Aug 8, 2024
- GILEAD SCIENCES, INC.
- Daniel Rohrer
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
ENGINEERED NON-HUMAN ANIMALS FOR PRODUCING ANTIBODIES
- Publication number 20240251767
- Publication date Aug 1, 2024
- Leveragen, Inc.
- Weisheng Victor CHEN
- C07 - ORGANIC CHEMISTRY
Information Patent Application
TRANSGENIC RAINBOW SHARK
- Publication number 20240251766
- Publication date Aug 1, 2024
- GloFish, LLC
- Alan Blake
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HUMAN IMMUNOGLOBULIN HEAVY CHAIN LONG CDR3 TRANSGENE CONSTRUCTS AND...
- Publication number 20240239919
- Publication date Jul 18, 2024
- GILEAD SCIENCES, INC.
- Daniel Rohrer
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RECOMBINANT GENOME, AND NON-HUMAN MAMMALIAN CELL AND PRODUCTION MET...
- Publication number 20240224963
- Publication date Jul 11, 2024
- Shanghai Acemab Corporation Ltd.
- Seehong WONG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR PREVENTING OR DELAYING PUBERTY IN PREP...
- Publication number 20240218038
- Publication date Jul 4, 2024
- The General Hospital Corporation
- Patricia K. DONAHOE
- C07 - ORGANIC CHEMISTRY
Information Patent Application
TRANSGENIC RODENTS EXPRESSING CHIMERIC EQUINE-RODENT ANTIBODIES AND...
- Publication number 20240215556
- Publication date Jul 4, 2024
- TRIANNI, INC.
- Werner MUELLER
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
ANIMAL MODELS AND THERAPEUTIC MOLECULES
- Publication number 20240206440
- Publication date Jun 27, 2024
- PETMEDIX LTD
- Albert Vilella BERTRAN
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
IL-17A BINDING PROTEINS
- Publication number 20240199731
- Publication date Jun 20, 2024
- Crescendo Biologics Limited
- Bryan EDWARDS
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Animal expressing industrially exogenous proteins

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Transgenic rainbow shark

ADAM6 mice

Method of treating rheumatoid arthritis using antibodies to oxidize...

Non-human animals having a humanized signal-regulatory protein gene

Camelization of a human variable domain by gene conversion

Transgenic animals and methods of use

Non-human animals having a humanized lymphocyte-activation gene 3

Human antibody-producing non-human animal and method for preparing...

Transgenic mouse for aglycosylated antibody production and use of a...

Recombinant protein production system

Human antibodies from transgenic rodents with multiple heavy chain...

Siglec transgenic mice and methods of use thereof

Genetically modified non-human animals with humanized immunoglobuli...

Genetically modified non-human animals with common light chain immu...

Method for producing recombinant proteins in insects

High-throughput mouse model for optimizing antibody affinities

Humanized IL-4 and IL-4Rα animals

ADAM6 mice

Long germline DH genes and long HCDR3 antibodies

Non-human animals expressing humanized CD3 complex

Antibody producing non-human animals

Methods, cells and organisms

Enhanced immunoglobulin diversity

Antibody production

Genetically modified non-human animals and methods for producing he...

Animal models and therapeutic molecules

Antibody producing non-human animals

Genetically modified non-human animals and methods of use thereof

High-throughput mouse model for optimizing antibody affinities

Genetically modified non-human animals expressing human EPO

Patents Applicationslast 30 patents

TRANSGENIC PURPLE BETTA AND METHODS OF MAKING THE SAME

TRANSGENIC MICE WITH HUMANIZED MHC I AND IMMUNOGLOBLUIN HEAVY CHAIN...

TRANSGENIC MICE WITH HUMANIZED MHC I AND IMMUNOGLOBLUIN HEAVY CHAIN...

TRANSGENIC MAMMALS AND METHODS OF USE THEREOF

NON-HUMAN ANIMALS HAVING A HUMANIZED LYMPHOCYTE-ACTIVATION GENE 3

MAMMALIAN ARTIFICIAL CHROMOSOME VECTOR HAVING HUMAN IMMUNOGLOBULIN...

HUMAN ANTIBODIES FROM TRANSGENIC RODENTS WITH MULTIPLE HEAVY CHAIN...

GENETICALLY MODIFIED NON-HUMAN ANIMALS WITH HUMANIZED IMMUNOGLOBULI...

TRANSGENIC TEAL TETRA

HUMAN LAMBDA LIGHT CHAIN MICE

MODIFIED EASTERN EQUINE ENCEPHALITIS VIRUSES, SELF-REPLICATING RNA...

TRANSGENIC CORY

NUCLEIC ACIDS ENCODING ANCHOR MODIFIED ANTIBODIES AND USES THEREOF

ADAM6 MICE

Non-Human Animals Expressing Humanized CD3 Complex

ANTI-CRISPR CONSTRUCT AND ITS USE TO COUNTERACT A CRISPR-BASED GENE...

TRANSGENIC CORY

GENETICALLY MODIFIED NON-HUMAN ANIMALS WITH COMMON LIGHT CHAIN IMMU...

ANTIBODY PRODUCTION

METHOD FOR PREPARING TRANSGENIC NON-HUMAN ANIMAL HAVING GENOME INCL...

METHOD FOR PRODUCING RECOMBINANT PROTEINS IN INSECTS

CHIMERIC TRANSGENIC IMMUNOGLOBULIN MICE WITH AN ALTERED HEAVY CHAIN...

ENGINEERED NON-HUMAN ANIMALS FOR PRODUCING ANTIBODIES

TRANSGENIC RAINBOW SHARK

HUMAN IMMUNOGLOBULIN HEAVY CHAIN LONG CDR3 TRANSGENE CONSTRUCTS AND...

RECOMBINANT GENOME, AND NON-HUMAN MAMMALIAN CELL AND PRODUCTION MET...

COMPOSITIONS AND METHODS FOR PREVENTING OR DELAYING PUBERTY IN PREP...

TRANSGENIC RODENTS EXPRESSING CHIMERIC EQUINE-RODENT ANTIBODIES AND...

ANIMAL MODELS AND THERAPEUTIC MOLECULES

IL-17A BINDING PROTEINS