Animals comprising multiple alterations of the genome, by transgenesis or homologous recombination

Industry

CPC
A01K2217/15

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Parent Industries

AHUMAN NECESSITIES A01Agriculture A01KANIMAL HUSBANDRY CARE OF BIRDS, FISHES, INSECTS FISHING REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR NEW BREEDS OF ANIMALS A01K2217/00Genetically modified animals

Current Industry

A01K2217/15Animals comprising multiple alterations of the genome, by transgenesis or homologous recombination

Industries

Patents Grantslast 30 patents

Information Patent Grant
High-throughput mouse model for optimizing antibody affinities
- Patent number 11,974,553
- Issue date May 7, 2024
- Children's Medical Center Corporation
- Frederick W. Alt
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Genetically modified mouse expressing human APOE4 and mouse Trem2 p...
- Patent number 11,957,115
- Issue date Apr 16, 2024
- The Jackson Laboratory
- Gareth Howell
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
ADAM6 mice
- Patent number 11,950,578
- Issue date Apr 9, 2024
- REGENERON PHARMACEUTICALS, INC.
- Lynn Macdonald
- B60 - VEHICLES IN GENERAL
Information Patent Grant
Non-human animals expressing humanized CD3 complex
- Patent number 11,937,587
- Issue date Mar 26, 2024
- REGENERON PHARMACEUTICALS, INC.
- Kara L. Olson
- G01 - MEASURING TESTING
Information Patent Grant
Platform for T lymphocyte genome engineering and in vivo high-throu...
- Patent number 11,926,839
- Issue date Mar 12, 2024
- Yale University
- Sidi Chen
- G01 - MEASURING TESTING
Information Patent Grant
Antibody producing non-human animals
- Patent number 11,925,174
- Issue date Mar 12, 2024
- Merus N.V.
- Ton Logtenberg
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Mouse having a humanized cluster of differentiation 47 gene
- Patent number 11,910,788
- Issue date Feb 27, 2024
- REGENERON PHARMACEUTICALS, INC.
- Cagan Gurer
- G01 - MEASURING TESTING
Information Patent Grant
Antibody production
- Patent number 11,877,565
- Issue date Jan 23, 2024
- Erasmus University Medical Center
- Roger Kingdon Craig
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Cas-ready mouse embryonic stem cells and mice and uses thereof
- Patent number 11,866,794
- Issue date Jan 9, 2024
- REGENERON PHARMACEUTICALS, INC.
- Guochun Gong
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Animal models and therapeutic molecules
- Patent number 11,812,731
- Issue date Nov 14, 2023
- Kymab Ltd.
- Allan Bradley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antibody producing non-human animals
- Patent number 11,785,924
- Issue date Oct 17, 2023
- Merus N.V.
- Ton Logtenberg
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
NSG mice lacking MHC class I and class II
- Patent number 11,778,994
- Issue date Oct 10, 2023
- The Jackson Laboratory
- Michael A. Brehm
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Genetically modified non-human animals and methods of use thereof
- Patent number 11,778,995
- Issue date Oct 10, 2023
- REGENERON PHARMACEUTICALS, INC.
- Richard Flavell
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
High-throughput mouse model for optimizing antibody affinities
- Patent number 11,771,069
- Issue date Oct 3, 2023
- Children's Medical Center Corporation
- Frederick W. Alt
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Genetically modified non-human animals expressing human EPO
- Patent number 11,766,032
- Issue date Sep 26, 2023
- REGENERON PHARMACEUTICALS, INC.
- Andrew J. Murphy
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Peromyscus animal model for cancer
- Patent number 11,766,033
- Issue date Sep 26, 2023
- University of South Carolina
- Vimala Kaza
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Gene expression system
- Patent number 11,737,436
- Issue date Aug 29, 2023
- Oxitec Limited
- Martha Koukidou
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
TRPC3 as a therapeutic target for alzheimer's disease
- Patent number 11,723,347
- Issue date Aug 15, 2023
- The Jackson Laboratory
- Catherine Kaczorowski
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Method for producing polyclonal antibodies with improved complement...
- Patent number 11,725,044
- Issue date Aug 15, 2023
- Xenothera
- Odile Duvaux
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Animals, repertoires and methods
- Patent number 11,707,056
- Issue date Jul 25, 2023
- Kymab Limited
- Allan Bradley
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
IL-17A binding proteins
- Patent number 11,667,705
- Issue date Jun 6, 2023
- Crescendo Biologics Limited
- Bryan Edwards
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Humanized non-human animals with restricted immunoglobulin heavy ch...
- Patent number 11,666,040
- Issue date Jun 6, 2023
- REGENERON PHARMACEUTICALS, INC.
- Lynn MacDonald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Double knockout (GT/CMAH-KO) pigs, organs and tissues
- Patent number 11,666,039
- Issue date Jun 6, 2023
- Indiana University Research and Technology Corporation
- A. Joseph Tector
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antibodies to oxidized phospholipids
- Patent number 11,655,288
- Issue date May 23, 2023
- The Regents of the University of California
- Joseph L. Witztum
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Humanized light chain mice
- Patent number 11,617,357
- Issue date Apr 4, 2023
- REGENERON PHARMACEUTICALS, INC.
- Lynn Macdonald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Humanized light chain mice
- Patent number 11,612,151
- Issue date Mar 28, 2023
- REGENERON PHARMACEUTICALS, INC.
- Lynn Macdonald
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Compositions and methods for genetically modifying myosin phosphata...
- Patent number 11,607,461
- Issue date Mar 21, 2023
- University of Maryland, Baltimore
- Steven A. Fisher
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Animal models and therapeutic molecules
- Patent number 11,606,941
- Issue date Mar 21, 2023
- Kymab Limited
- Allan Bradley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Mouse model of DITRA disease and uses thereof
- Patent number 11,589,562
- Issue date Feb 28, 2023
- Regeneran Pharmaceuticals, Inc.
- Andrew J. Murphy
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Recombinant adenovirus-based interferon biotherapeutics in swine
- Patent number 11,582,956
- Issue date Feb 21, 2023
- The United States of America, as represented by the Secretary of Agriculture
- James J. Zhu
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING

Patents Applicationslast 30 patents

Information Patent Application
NON-HUMAN ANIMALS HAVING A HUMANIZED CLUSTER OF DIFFERENTIATION 47...
- Publication number 20240138384
- Publication date May 2, 2024
- Regeneron Pharmaceuticals, Inc.
- Cagan Gurer
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Genetically modified non-human having humanized gamma and delta TCR...
- Publication number 20240114883
- Publication date Apr 11, 2024
- inGenious Targeting Laboratories
- Wei Weng
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
TRPC3 AS A THERAPEUTIC TARGET FOR ALZHEIMER’S DISEASE
- Publication number 20240099277
- Publication date Mar 28, 2024
- The Jackson Laboratory
- Catherine Kaczorowski
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CAS-READY MOUSE EMBRYONIC STEM CELLS AND MICE AND USES THEREOF
- Publication number 20240093316
- Publication date Mar 21, 2024
- Regeneron Pharmaceuticals, Inc.
- Guochun Gong
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHOD OF PREPARING ANTIBODY CARRYING A UNIVERSAL SITE-DIRECTED COU...
- Publication number 20240081302
- Publication date Mar 14, 2024
- UNOGEN BIOTECHNOLOGY CO., LTD.
- Tao CHEN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMALS EXPRESSING HUMAN EPO
- Publication number 20240074414
- Publication date Mar 7, 2024
- Regeneron Pharmaceuticals, Inc.
- Andrew J. Murphy
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
HUMANIZED NON-HUMAN ANIMALS WITH RESTRICTED IMMUNOGLOBULIN HEAVY CH...
- Publication number 20240065238
- Publication date Feb 29, 2024
- Regeneron Pharmaceuticals, Inc.
- Lynn Macdonald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Animal Models and Therapeutic Molecules
- Publication number 20240057572
- Publication date Feb 22, 2024
- Kymab Limited
- Allan BRADLEY
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HEAVY CHAIN-ONLY ANTIBODIES
- Publication number 20240023526
- Publication date Jan 25, 2024
- TRIANNI, INC.
- Matthias Wabl
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
ANTIBODY PRODUCING NON-HUMAN ANIMALS
- Publication number 20240023527
- Publication date Jan 25, 2024
- Merus N.V.
- Ton LOGTENBERG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Gene Expression System
- Publication number 20240016132
- Publication date Jan 18, 2024
- Oxitec Limited
- Martha KOUKIDOU
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC GLP1R
- Publication number 20230363362
- Publication date Nov 16, 2023
- Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
- Yuelei Shen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTIBODIES TO OXIDIZED PHOSPHOLIPIDS
- Publication number 20230357376
- Publication date Nov 9, 2023
- The Regents of the University of California
- Joseph L. Witztum
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
HUMANIZED LIGHT CHAIN MICE
- Publication number 20230337646
- Publication date Oct 26, 2023
- Regeneron Pharmaceuticals, Inc.
- Lynn Macdonald
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
ANIMAL MODEL, METHODS FOR MAKING AND USING THEREOF, AND COMPOSITION...
- Publication number 20230309522
- Publication date Oct 5, 2023
- City University of Hong Kong
- Sungchil YANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMALS AND METHODS OF USE THEREOF
- Publication number 20230292721
- Publication date Sep 21, 2023
- Regeneron Pharmaceuticals, Inc.
- Dietmar Herndler-Brandstetter
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
HUMANIZED RODENTS FOR TESTING THERAPEUTIC AGENTS
- Publication number 20230277692
- Publication date Sep 7, 2023
- Regeneron Pharmaceuticals, Inc.
- Vera VORONINA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Animal Models and Therapeutic Molecules
- Publication number 20230270088
- Publication date Aug 31, 2023
- Kymab Limited
- Allan Bradley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Animal Models and Therapeutic Molecules
- Publication number 20230263143
- Publication date Aug 24, 2023
- Kymab Limited
- Allan Bradley
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
ANIMAL MODEL OF BRAIN TUMOR AND MANUFACTURING METHOD OF ANIMAL MODEL
- Publication number 20230232794
- Publication date Jul 27, 2023
- Korea Advanced Institute of Science and Technology
- SEOK GU KANG
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMAL EXPRESSING A B2M/FCRN FUSION...
- Publication number 20230227531
- Publication date Jul 20, 2023
- Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
- Yuelei Shen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TISSUE SELECTIVE TRANSGENE EXPRESSION
- Publication number 20230203531
- Publication date Jun 29, 2023
- Encoded Therapeutics, Inc.
- Stephanie TAGLIATELA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NON-HUMAN ANIMALS HAVING A HUMANIZED CXCL13 GENE
- Publication number 20230172170
- Publication date Jun 8, 2023
- Regeneron Pharmaceuticals, Inc.
- Davor FRLETA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC CD94 A...
- Publication number 20230172171
- Publication date Jun 8, 2023
- Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
- Yuelei Shen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MOUSE MODEL OF DITRA DISEASE AND USES THEREOF
- Publication number 20230172172
- Publication date Jun 8, 2023
- Regeneron Pharmaceuticals, Inc.
- Andrew J. Murphy
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANIMAL MODELS AND THERAPEUTIC MOLECULES
- Publication number 20230157264
- Publication date May 25, 2023
- Kymab Limited
- E-Chiang LEE
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC CD38
- Publication number 20230148574
- Publication date May 18, 2023
- Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
- Yuelei Shen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NON-HUMAN ANIMAL SECRETOME MODELS
- Publication number 20230141187
- Publication date May 11, 2023
- University of Pittsburgh of the Commonwealth System of Higher Education
- Jie Liu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TRANSGENIC MICE
- Publication number 20230133028
- Publication date May 4, 2023
- Crescendo Biologics Limited
- Yumin Teng
- C07 - ORGANIC CHEMISTRY
Information Patent Application
TGFbeta1 Hyperactivation Causes Gender-Specific Calcific Aortic Ste...
- Publication number 20230040639
- Publication date Feb 9, 2023
- University of South Carolina
- Mohamad Azhar
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING

Animals comprising multiple alterations of the genome, by transgenesis or homologous recombination

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

High-throughput mouse model for optimizing antibody affinities

Genetically modified mouse expressing human APOE4 and mouse Trem2 p...

ADAM6 mice

Non-human animals expressing humanized CD3 complex

Platform for T lymphocyte genome engineering and in vivo high-throu...

Antibody producing non-human animals

Mouse having a humanized cluster of differentiation 47 gene

Antibody production

Cas-ready mouse embryonic stem cells and mice and uses thereof

Animal models and therapeutic molecules

Antibody producing non-human animals

NSG mice lacking MHC class I and class II

Genetically modified non-human animals and methods of use thereof

High-throughput mouse model for optimizing antibody affinities

Genetically modified non-human animals expressing human EPO

Peromyscus animal model for cancer

Gene expression system

TRPC3 as a therapeutic target for alzheimer's disease

Method for producing polyclonal antibodies with improved complement...

Animals, repertoires and methods

IL-17A binding proteins

Humanized non-human animals with restricted immunoglobulin heavy ch...

Double knockout (GT/CMAH-KO) pigs, organs and tissues

Antibodies to oxidized phospholipids

Humanized light chain mice

Humanized light chain mice

Compositions and methods for genetically modifying myosin phosphata...

Animal models and therapeutic molecules

Mouse model of DITRA disease and uses thereof

Recombinant adenovirus-based interferon biotherapeutics in swine

Patents Applicationslast 30 patents

NON-HUMAN ANIMALS HAVING A HUMANIZED CLUSTER OF DIFFERENTIATION 47...

Genetically modified non-human having humanized gamma and delta TCR...

TRPC3 AS A THERAPEUTIC TARGET FOR ALZHEIMER’S DISEASE

CAS-READY MOUSE EMBRYONIC STEM CELLS AND MICE AND USES THEREOF

METHOD OF PREPARING ANTIBODY CARRYING A UNIVERSAL SITE-DIRECTED COU...

GENETICALLY MODIFIED NON-HUMAN ANIMALS EXPRESSING HUMAN EPO

HUMANIZED NON-HUMAN ANIMALS WITH RESTRICTED IMMUNOGLOBULIN HEAVY CH...

Animal Models and Therapeutic Molecules

HEAVY CHAIN-ONLY ANTIBODIES

ANTIBODY PRODUCING NON-HUMAN ANIMALS

Gene Expression System

GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC GLP1R

ANTIBODIES TO OXIDIZED PHOSPHOLIPIDS

HUMANIZED LIGHT CHAIN MICE

ANIMAL MODEL, METHODS FOR MAKING AND USING THEREOF, AND COMPOSITION...

GENETICALLY MODIFIED NON-HUMAN ANIMALS AND METHODS OF USE THEREOF

HUMANIZED RODENTS FOR TESTING THERAPEUTIC AGENTS

Animal Models and Therapeutic Molecules

Animal Models and Therapeutic Molecules

ANIMAL MODEL OF BRAIN TUMOR AND MANUFACTURING METHOD OF ANIMAL MODEL

GENETICALLY MODIFIED NON-HUMAN ANIMAL EXPRESSING A B2M/FCRN FUSION...

TISSUE SELECTIVE TRANSGENE EXPRESSION

NON-HUMAN ANIMALS HAVING A HUMANIZED CXCL13 GENE

GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC CD94 A...

MOUSE MODEL OF DITRA DISEASE AND USES THEREOF

ANIMAL MODELS AND THERAPEUTIC MOLECULES

GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC CD38

NON-HUMAN ANIMAL SECRETOME MODELS

TRANSGENIC MICE

TGFbeta1 Hyperactivation Causes Gender-Specific Calcific Aortic Ste...