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Animals genetically altered by homologous recombination
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A01K2217/07
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HUMAN NECESSITIES
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ANIMAL HUSBANDRY CARE OF BIRDS, FISHES, INSECTS FISHING REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR NEW BREEDS OF ANIMALS
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Genetically modified animals
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Animals genetically altered by homologous recombination
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Patents Grants
last 30 patents
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Patent Grant
Immunoglobulin lambda light chain and uses thereof
Patent number
12,356,967
Issue date
Jul 15, 2025
REGENERON PHARMACEUTICALS, INC.
Andrew J. Murphy
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Efficient protein expression in vivo using modified RNA (mod-RNA)
Patent number
12,357,675
Issue date
Jul 15, 2025
The General Hospital Corporation
Kenneth R. Chien
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Methods for producing antigen-binding proteins against foreign anti...
Patent number
12,342,801
Issue date
Jul 1, 2025
REGENERON PHARMACEUTICALS, INC.
Vera Voronina
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Immunodeficient non-human animal
Patent number
12,342,800
Issue date
Jul 1, 2025
Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
Yuelei Shen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Humanized IL-4 and IL-4Rα animals
Patent number
12,310,340
Issue date
May 27, 2025
REGENERON PHARMACEUTICALS, INC.
Li-Hsien Wang
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Non-human animals expressing exogenous terminal deoxynucleotidyltra...
Patent number
12,295,354
Issue date
May 13, 2025
REGENERON PHARMACEUTICALS, INC.
Lynn Macdonald
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Gene therapy for haploinsufficiency
Patent number
12,285,496
Issue date
Apr 29, 2025
The Regents of the University of California
Nadav Ahituv
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Polypeptide set to be used in light dependent gene recombination
Patent number
12,286,650
Issue date
Apr 29, 2025
The University of Tokyo
Moritoshi Sato
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Use of ZC3H12B gene or protein and method for establishing animal m...
Patent number
12,282,023
Issue date
Apr 22, 2025
Shanghai Ocean University
Guijun Guan
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Viable genetically modified sheep with an inactivated alpha-1,3-gal...
Patent number
12,275,947
Issue date
Apr 15, 2025
FIOS THERAPEUTICS, LLC
Christopher G. A. McGregor
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for treating non-age-associated hearing im...
Patent number
12,264,317
Issue date
Apr 1, 2025
Akouos, Inc.
Emmanuel John Simons
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Humanized dipeptidyl-peptidase IV (DPP4) animals
Patent number
12,256,720
Issue date
Mar 25, 2025
REGENERON PHARMACEUTICALS, INC.
Christos Kyratsous
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Optimized mini-dystrophin genes and expression cassettes and their use
Patent number
12,257,321
Issue date
Mar 25, 2025
The University of North Carolina at Chapel Hill
Xiao Xiao
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Grant
Delivery, Engineering and optimization of systems, methods and comp...
Patent number
12,252,707
Issue date
Mar 18, 2025
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Method for genetic manipulation of sap-feeding insects
Patent number
12,245,576
Issue date
Mar 11, 2025
The Regents of the University of California
Peter W. Atkinson
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Humanized IL-6 and IL-6 receptor
Patent number
12,239,111
Issue date
Mar 4, 2025
REGENERON PHARMACEUTICALS, INC.
Li-Hsien Wang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Pathogen-resistant animals having modified CD163 genes
Patent number
12,225,889
Issue date
Feb 18, 2025
The Curators of the University of Missouri
Randall S. Prather
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Pathogen-resistant animals having modified CD163 genes
Patent number
12,219,939
Issue date
Feb 11, 2025
The Curators of the University of Missouri
Randall S. Prather
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oplophorus-derived luciferases, novel coelenterazine substrates, an...
Patent number
12,215,375
Issue date
Feb 4, 2025
Promega Corporation
Brock Binkowski
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
ADAM6 mice
Patent number
12,207,628
Issue date
Jan 28, 2025
REGENERON PHARMACEUTICALS, INC.
Lynn Macdonald
B60 - VEHICLES IN GENERAL
Information
Patent Grant
Animal model of mucopolysaccharidoses type IVA
Patent number
12,201,095
Issue date
Jan 21, 2025
ESTEVE PHARMACEUTICALS, S.A.
Maria-Fátima Bosch-Tubert
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Non-human animals comprising a humanized coagulation factor 12 locus
Patent number
12,201,096
Issue date
Jan 21, 2025
REGENERON PHARMACEUTICALS, INC.
Yajun Tang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Manufacture of active highly phosphorylated human lysosomal sulfata...
Patent number
12,188,058
Issue date
Jan 7, 2025
Biomarin Pharmaceutical Inc.
Erno Pungor
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Phosphorylated dicer antibody and methods of use thereof
Patent number
12,173,084
Issue date
Dec 24, 2024
Board of Regents, The University of Texas System
Swathi Arur
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Non-human animals having a humanized signal-regulatory protein gene
Patent number
12,161,097
Issue date
Dec 10, 2024
REGENERON PHARMACEUTICALS, INC.
Andrew J. Murphy
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
VISTA-Ig constructs and the use of VISTA-Ig for treatment of autoim...
Patent number
12,162,928
Issue date
Dec 10, 2024
The Trustees of Dartmouth College
Randolph J. Noelle
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Compositions and methods for modulating neuronal excitability and m...
Patent number
12,163,130
Issue date
Dec 10, 2024
Icahn School of Medicine at Mount Sinai
Anne Schaefer
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Therapies with lanthionine C-like protein 2 ligands and cells prepa...
Patent number
12,150,961
Issue date
Nov 26, 2024
NImmune Biopharma, Inc.
Josep Bassaganya-Riera
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Dominant active yap, a hippo effector, induces chromatin accessibil...
Patent number
12,138,284
Issue date
Nov 12, 2024
Baylor College of Medicine
Tanner Monroe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Humanized M-CSF mice
Patent number
12,127,536
Issue date
Oct 29, 2024
REGENERON PHARMACEUTICALS, INC.
Andrew J. Murphy
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Patents Applications
last 30 patents
Information
Patent Application
GENETICALLY MODIFIED NON-HUMAN MAMMALS, PREPARATION METHODS THEREFO...
Publication number
20250234846
Publication date
Jul 24, 2025
RENGENE BIOTECHNOLOGY CO., LTD.
Haoyi WANG
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
GENE THERAPY FOR HAPLOINSUFFICIENCY
Publication number
20250228980
Publication date
Jul 17, 2025
The Regents of the University of California
Nadav Ahituv
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENETICALLY MODIFIED MOUSE MODELS OF ALZHEIMER’S DISEASE
Publication number
20250228219
Publication date
Jul 17, 2025
The Jackson Laboratory
Gareth Howell
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
VIABLE GALACTOSYLTRANSFERASE KNOCK-OUT SHEEP AND RELATED METHODS
Publication number
20250215450
Publication date
Jul 3, 2025
FIOS THERAPEUTICS, LLC
Christopher G. A. McGregor
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
IMMUNODEFICIENT FCGR1 KNOCKOUT MOUSE MODELS
Publication number
20250212854
Publication date
Jul 3, 2025
The Jackson Laboratory
Leonard D. Shultz
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
PATHOGEN-RESISTANT ANIMALS HAVING MODIFIED CD163 GENES
Publication number
20250212855
Publication date
Jul 3, 2025
THE CURATORS OF THE UNIVERSITY OF MISSOURI
Randall S. Prather
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENETICALLY MODIFIED MOUSE, METHODS FOR PRODUCING THE SAME, AND USE...
Publication number
20250212856
Publication date
Jul 3, 2025
Mackay Memorial Hospital
Kate HSU
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANIMAL MODEL GENERATING HUMANIZED ANTIBODY AND CONSTRUCTION METHOD...
Publication number
20250212857
Publication date
Jul 3, 2025
GEMPHARMATECH CO., LTD.
Mingkun ZHANG
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
COMPOSITIONS AND METHODS FOR DEFINING OPTIMAL TREATMENT TIMEFRAMES...
Publication number
20250194571
Publication date
Jun 19, 2025
Regeneron Pharmaceuticals, Inc.
Elizabeth Hwang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMALS WITH HUMANIZED IMMUNOGLOBULI...
Publication number
20250185635
Publication date
Jun 12, 2025
Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
Yuelei Shen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TELOMERASE REVERSE TRANSCRIPTASE THERAPY FOR KIDNEY FIBROSIS AND NO...
Publication number
20250176509
Publication date
Jun 5, 2025
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOL...
Maria Antonia BLASCO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BMX MOUSE MODELS FOR BECKER MUSCULAR DYSTROPHY (BMD) V
Publication number
20250176510
Publication date
Jun 5, 2025
Children's National Medical Center
Alyson Fiorillo
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
METHOD FOR GENETIC MANIPULATION OF SAP-FEEDING INSECTS
Publication number
20250176512
Publication date
Jun 5, 2025
The Regents of the University of California
Peter W. Atkinson
G01 - MEASURING TESTING
Information
Patent Application
USE OF miR-34b IN REGULATING LIPID METABOLISM OF SHANDONG BLACK CATTLE
Publication number
20250163413
Publication date
May 22, 2025
Qingdao Agricultural University
Yajuan DONG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
THERAPIES WITH LANTHIONINE C-LIKE PROTEIN 2 LIGANDS AND CELLS PREPA...
Publication number
20250163377
Publication date
May 22, 2025
NImmune Biopharma, Inc.
Josep Bassaganya-Riera
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
FISH, METHOD FOR PRODUCING FISH, AND METHOD FOR PRODUCING FISH EXHI...
Publication number
20250160306
Publication date
May 22, 2025
KYOTO UNIVERSITY
Masato KINOSHITA
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
TRANS-SPLICING METHODS AND COMPOSITIONS FOR GENERATION OF SINGLE SE...
Publication number
20250151704
Publication date
May 15, 2025
Joseph Fenton LAWLER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TRANSGENIC MOUSE
Publication number
20250134078
Publication date
May 1, 2025
Seiho NAGAFUCHI
C07 - ORGANIC CHEMISTRY
Information
Patent Application
MICRORNA INHIBITOR THERAPY IN SYSTEMIC LUPUS ERYTHEMATOSUS
Publication number
20250127149
Publication date
Apr 24, 2025
Wael N. JARJOUR
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TRIPLE TRANSGENIC PIGS SUITABLE FOR XENOGRAFT
Publication number
20250120373
Publication date
Apr 17, 2025
Indiana University Research and Technology Corp
A. Joseph Tector
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC GENES
Publication number
20250120374
Publication date
Apr 17, 2025
Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
Xiaofei Zhou
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
GENETICALLY MODIFIED MOUSE MODELS AND METHODS OF USE THEREOF
Publication number
20250113809
Publication date
Apr 10, 2025
University of South Florida
Lianchun Wang
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
Genetic Modifications for Xenotransplantation
Publication number
20250098652
Publication date
Mar 27, 2025
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
Megan Sykes
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENETICALLY MODIFIED MICE FOR PREPARING ANTIBODIES AND PREPARATION...
Publication number
20250089690
Publication date
Mar 20, 2025
CYAGEN BIOSCIENCES (SUZHOU) INC.
Lanqing HAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENOMIC SAFE HARBORS
Publication number
20250087304
Publication date
Mar 13, 2025
Synteny Therapeutics, Inc.
Robert KOTIN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING NEURONAL EXCITABILITY AND M...
Publication number
20250075215
Publication date
Mar 6, 2025
Icahn School of Medicine at Mount Sinai
Anne SCHAEFER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Humanized M-CSF Mice
Publication number
20250072406
Publication date
Mar 6, 2025
Regeneron Pharmaceuticals, Inc.
Andrew J. Murphy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Genetically Modified Non-Human Animals And Methods Of Use Thereof
Publication number
20250072405
Publication date
Mar 6, 2025
Regeneron Pharmaceuticals, Inc.
Richard Flavell
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DOMINANT ACTIVE YAP, A HIPPO EFFECTOR, INDUCES CHROMATIN ACCESSIBIL...
Publication number
20250073276
Publication date
Mar 6, 2025
Baylor College of Medicine
Tanner Monroe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
EDITING TMPRSS2/4 FOR DISEASE RESISTANCE IN LIVESTOCK
Publication number
20250064032
Publication date
Feb 27, 2025
Pig Improvement Company UK Limited
Andrew Mark Cigan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...