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Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
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Antibody mimetics or scaffolds
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C07K2318/20
Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
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Patents Grants
last 30 patents
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Patent Grant
Scaffold proteins
Patent number
11,952,415
Issue date
Apr 9, 2024
Avacta Life Sciences Limited
Geoffrey William Platt
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Switch molecule and switchable chimeric antigen receptor
Patent number
11,945,878
Issue date
Apr 2, 2024
ABCLON INC.
Jong Seo Lee
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Fibronectin based scaffold domain proteins that bind PCSK9
Patent number
11,858,979
Issue date
Jan 2, 2024
Bristol-Meyers Squibb Company
Ray Camphausen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Serum albumin-binding fibronectin type III domains
Patent number
11,833,190
Issue date
Dec 5, 2023
Janssen Biotech, Inc.
Michael Diem
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Multi-chain polypeptide-containing tri-specific binding molecules
Patent number
11,820,818
Issue date
Nov 21, 2023
MacroGenics, Inc.
Leslie S. Johnson
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Citrate buffered VEGF antagonist formulations
Patent number
11,806,398
Issue date
Nov 7, 2023
REGENERON PHARMACEUTICALS, INC.
Daniel B. Dix
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Lipocalin muteins with binding affinity for LAG-3
Patent number
11,773,147
Issue date
Oct 3, 2023
Pieris Pharmaceuticals GmbH
Christine Rothe
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Cysteine engineered fibronectin type III domain binding molecules
Patent number
11,702,475
Issue date
Jul 18, 2023
Janssen Biotech, Inc.
Shalom Goldberg
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Tri-specific binding molecules that specifically bind to multiple c...
Patent number
11,697,684
Issue date
Jul 11, 2023
MacroGenics, Inc.
Ezio Bonvini
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
EGFR binding molecules
Patent number
11,629,193
Issue date
Apr 18, 2023
F-star Therapeutics Limited
Mihriban Tuna
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Designed ankyrin repeat domains with altered surface residues
Patent number
11,578,427
Issue date
Feb 14, 2023
Molecular Partners AG
Hans Kaspar Binz
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Methods of administering a composition comprising a Tn3 scaffold an...
Patent number
11,555,062
Issue date
Jan 17, 2023
Viela Bio, Inc.
Anthony Coyle
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
DPP3 binder directed to and binding to specific DPP3-epitopes and i...
Patent number
11,530,276
Issue date
Dec 20, 2022
4TEEN4 Pharmaceuticals GmbH
Andreas Bergmann
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Chimeric proteins
Patent number
11,525,133
Issue date
Dec 13, 2022
Cambridge Enterprise Limited
Laura Itzhaki
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Cell surface conjugates and related cell compositions and methods
Patent number
11,517,627
Issue date
Dec 6, 2022
Juno Therapeutics GmbH
Lothar Germeroth
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Multifunctional heteromultimeric constructs
Patent number
11,518,791
Issue date
Dec 6, 2022
Luxembourg Institute of Health (LIH)
Xavier Dervillez
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Synthetic immunoglobulin domains with binding properties engineered...
Patent number
11,499,249
Issue date
Nov 15, 2022
F-star Therapeutics Limited
Gottfried Himmler
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Method for generating high affinity, bivalent binding agents for sa...
Patent number
11,473,080
Issue date
Oct 18, 2022
The Board of Trustees of the University of Illinois
Brian K. Kay
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Antibody derivatives with conditionally enabled effector function
Patent number
11,466,093
Issue date
Oct 11, 2022
The General Hospital Corporation
Glen S. Cho
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
PSMA-specific binding proteins
Patent number
11,464,877
Issue date
Oct 11, 2022
Arne Skerra
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Bispecific T cell activating antigen binding molecules
Patent number
11,459,404
Issue date
Oct 4, 2022
Roche Glycart AG
Marina Bacac
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods and composition for modifying enzymes
Patent number
11,459,400
Issue date
Oct 4, 2022
The University of Chicago
Shohei Koide
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Insertable variable fragments of antibodies and modified A1-A2 doma...
Patent number
11,453,713
Issue date
Sep 27, 2022
Xyphos Biosciences Inc.
Kyle Landgraf
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Designed ankyrin repeat proteins binding to hepatocyte growth factor
Patent number
11,453,708
Issue date
Sep 27, 2022
Molecular Partners AG
Gaby Tresch
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
PD-L1 binding fibronectin type III domains
Patent number
11,447,539
Issue date
Sep 20, 2022
Janssen Biotech, Inc.
Michael Diem
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Fibronectin based scaffold proteins
Patent number
11,447,538
Issue date
Sep 20, 2022
Bristol-Myers Squibb Company
Dasa Lipovsek
G01 - MEASURING TESTING
Information
Patent Grant
Anti-thyroglobulin T cell receptors
Patent number
11,440,956
Issue date
Sep 13, 2022
The United States of America, as represented by the Secretary, Department of...
Kenichi Hanada
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
OB-fold used as scaffold for engineering new specific binders
Patent number
11,434,585
Issue date
Sep 6, 2022
Institut Pasteur
Frederic Pecorari
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Trifunctional T cell-antigen coupler and methods and uses thereof
Patent number
11,421,014
Issue date
Aug 23, 2022
McMaster University
Jonathan Bramson
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Fibronectin binding domains with reduced immunogenicity
Patent number
11,408,093
Issue date
Aug 9, 2022
Bristol-Myers Squibb Company
Jonathan Davis
C40 - COMBINATORIAL CHEMISTRY
Patents Applications
last 30 patents
Information
Patent Application
NEW HER2-BINDING POLYPEPTIDE
Publication number
20240124533
Publication date
Apr 18, 2024
AFFIBODY AB
Fredrik FREJD
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TRI-SPECIFIC BINDING MOLECULES THAT SPECIFICALLY BIND TO MULTIPLE C...
Publication number
20240117036
Publication date
Apr 11, 2024
MacroGenics, Inc.
Ezio BONVINI
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Heteromultivalent Nucleic Acid Scaffolds and Uses Thereof
Publication number
20240084044
Publication date
Mar 14, 2024
George Mason University
Amanda Haymond Still
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RECOMBINANT CD3 BINDING PROTEINS AND THEIR USE
Publication number
20240052033
Publication date
Feb 15, 2024
Molecular Partners AG
Sebastian GRIMM
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
DE NOVO BINDING DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF
Publication number
20240043550
Publication date
Feb 8, 2024
SUBDOMAIN, LLC
David William LAFLEUR
C07 - ORGANIC CHEMISTRY
Information
Patent Application
N-Terminal Capping Modules of Ankyrin Repeat Domains
Publication number
20240043481
Publication date
Feb 8, 2024
Athebio AG
Patrik Forrer
C07 - ORGANIC CHEMISTRY
Information
Patent Application
NPC1 MONOBODIES AND MONOBODY CONJUGATES THEREOF
Publication number
20240025969
Publication date
Jan 25, 2024
NEW YORK UNIVERSITY
Craig RAMIREZ
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TESTOSTERONE-SPECIFIC AFFIBODY AND USES THEREOF
Publication number
20240018233
Publication date
Jan 18, 2024
INSSEN INC.
Hye-Sun PARK
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ANTIBODY-LIKE PROTEIN AND USE THEREOF
Publication number
20230391893
Publication date
Dec 7, 2023
CELLEMEDY CO.,LTD
Jee Won LEE
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
MULTIMERIC PROTEIN COMPLEXES AS ANTIBODY SUBSTITUTES FOR NEUTRALIZA...
Publication number
20230382977
Publication date
Nov 30, 2023
The Regents of the University of California
Daniel L. COX
C07 - ORGANIC CHEMISTRY
Information
Patent Application
LENTIVIRAL VECTORS ENABLING ROUTING ANTIGENS TO MHC-II PATHWAY AND...
Publication number
20230364216
Publication date
Nov 16, 2023
INSTITUT PASTEUR
Pierre CHARNEAU
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENGINEERED BINDING PROTEINS FOR RECOGNITION OF BACTERIA
Publication number
20230358742
Publication date
Nov 9, 2023
Massachusetts Institute of Technology
Hadley Sikes Johnson
G01 - MEASURING TESTING
Information
Patent Application
SERUM STABLE BINDING PROTEINS FOR HUMAN HER2 FOR THERANOSTIC APPLIC...
Publication number
20230322946
Publication date
Oct 12, 2023
Navigo Proteins GmbH
Eva Bosse-Doenecke
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Antibody Derivatives with Conditionally Enabled Effector Function
Publication number
20230303709
Publication date
Sep 28, 2023
The General Hospital Corporation
Glen S. CHO
C07 - ORGANIC CHEMISTRY
Information
Patent Application
DPP3 BINDER DIRECTED TO AND BINDING TO SPECIFIC DPP3-EPITOPES AND I...
Publication number
20230295344
Publication date
Sep 21, 2023
4TEEN4 PHARMACEUTICALS GMBH
Andreas BERGMANN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
CELL SURFACE CONJUGATES AND RELATED CELL COMPOSITIONS AND METHODS
Publication number
20230190952
Publication date
Jun 22, 2023
Juno Therapeutics GmbH
Lothar GERMEROTH
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Multifunctional Heteromultimeric Constructs
Publication number
20230130737
Publication date
Apr 27, 2023
Luxembourg Institute of Health (LIH)
Xavier Dervillez
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
VARIANTS OF SAC7D AND THEIR USE IN CANCER THERAPY
Publication number
20230120167
Publication date
Apr 20, 2023
AFFILOGIC
Mathieu CINIER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Multivalent D-Peptidic Compounds for Target Proteins
Publication number
20230051872
Publication date
Feb 16, 2023
Reflexion Pharmaceuticals, Inc.
Paul Marinec
C07 - ORGANIC CHEMISTRY
Information
Patent Application
INSERTABLE VARIABLE FRAGMENTS OF ANTIBODIES AND MODIFIED A1-A2 DOMA...
Publication number
20230002475
Publication date
Jan 5, 2023
XYPHOS BIOSCIENCES INC.
Kyle LANDGRAF
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CHIMERIC RECEPTOR SENSORS
Publication number
20220396609
Publication date
Dec 15, 2022
Senti Biosciences, Inc.
Russell Morrison Gordley
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
A PEPTIDE FOR THE DELIVERY OF ANIONIC MATERIALS
Publication number
20220389059
Publication date
Dec 8, 2022
The Queen's University of Belfast
Helen MCCARTHY
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TRIFUNCTIONAL T CELL-ANTIGEN COUPLER AND METHODS AND USES THEREOF
Publication number
20220332790
Publication date
Oct 20, 2022
McMaster University
Jonathan Bramson
C07 - ORGANIC CHEMISTRY
Information
Patent Application
COMPOSITIONS AND METHODS FOR TREATING CANCER
Publication number
20220324963
Publication date
Oct 13, 2022
THE TRUSTEES OF THE UNIVERITY OF PENNSYLVANIA
Daniel J. Powell
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ENGINEERED T CELLS AND USES THEREFOR
Publication number
20220296690
Publication date
Sep 22, 2022
Pieris Pharmaceuticals GmbH
Marlon Hinner
C07 - ORGANIC CHEMISTRY
Information
Patent Application
RECOMBINANT 4-1BB BINDING PROTEINS AND THEIR USE
Publication number
20220298212
Publication date
Sep 22, 2022
Molecular Partners AG
Christian REICHEN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SINGLE CHAIN FUSIONCONSTRUCTS COMPRISING MULTIMERIC ANTIBODY FRAGME...
Publication number
20220281985
Publication date
Sep 8, 2022
LEADARTIS, S.L.
Luis ÁLVAREZ VALLINA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RECOMBINANT FAP BINDING PROTEINS AND THEIR USE
Publication number
20220242973
Publication date
Aug 4, 2022
Molecular Partners AG
Ulrike FIEDLER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ANTI-ADRENOMEDULLIN (ADM) BINDER FOR USE IN THERAPY OR PREVENTION O...
Publication number
20220227854
Publication date
Jul 21, 2022
ADRENOMED AG
Andreas BERGMANN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BINDING MOLECULES BINDING PD-L1 AND LAG-3
Publication number
20220185894
Publication date
Jun 16, 2022
F-star Therapeutics Limited
Jamie Campbell
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE