Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics

Industry

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C07K2318/20

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Parent Industries

CCHEMISTRY METALLURGY C07Organic chemistry C07KPEPTIDES C07K2318/00Antibody mimetics or scaffolds

Current Industry

C07K2318/20Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics

Industries

Patents Grantslast 30 patents

Information Patent Grant
Optimized variants of anti-VEGF antibodies
- Patent number 12,121,586
- Issue date Oct 22, 2024
- Genentech, Inc.
- Patrick Koenig
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
IL-IR-I binding polypeptide
- Patent number 12,116,397
- Issue date Oct 15, 2024
- Swedish Orphan Biovitrum AB (publ)
- Joachim Feldwisch
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Peptide for the delivery of anionic materials
- Patent number 12,049,519
- Issue date Jul 30, 2024
- The Queen's University of Belfast
- Helen McCarthy
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Scaffold proteins
- Patent number 11,952,415
- Issue date Apr 9, 2024
- Avacta Life Sciences Limited
- Geoffrey William Platt
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Switch molecule and switchable chimeric antigen receptor
- Patent number 11,945,878
- Issue date Apr 2, 2024
- ABCLON INC.
- Jong Seo Lee
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Fibronectin based scaffold domain proteins that bind PCSK9
- Patent number 11,858,979
- Issue date Jan 2, 2024
- Bristol-Meyers Squibb Company
- Ray Camphausen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Serum albumin-binding fibronectin type III domains
- Patent number 11,833,190
- Issue date Dec 5, 2023
- Janssen Biotech, Inc.
- Michael Diem
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Multi-chain polypeptide-containing tri-specific binding molecules
- Patent number 11,820,818
- Issue date Nov 21, 2023
- MacroGenics, Inc.
- Leslie S. Johnson
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Citrate buffered VEGF antagonist formulations
- Patent number 11,806,398
- Issue date Nov 7, 2023
- REGENERON PHARMACEUTICALS, INC.
- Daniel B. Dix
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Lipocalin muteins with binding affinity for LAG-3
- Patent number 11,773,147
- Issue date Oct 3, 2023
- Pieris Pharmaceuticals GmbH
- Christine Rothe
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Cysteine engineered fibronectin type III domain binding molecules
- Patent number 11,702,475
- Issue date Jul 18, 2023
- Janssen Biotech, Inc.
- Shalom Goldberg
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Tri-specific binding molecules that specifically bind to multiple c...
- Patent number 11,697,684
- Issue date Jul 11, 2023
- MacroGenics, Inc.
- Ezio Bonvini
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
EGFR binding molecules
- Patent number 11,629,193
- Issue date Apr 18, 2023
- F-star Therapeutics Limited
- Mihriban Tuna
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Designed ankyrin repeat domains with altered surface residues
- Patent number 11,578,427
- Issue date Feb 14, 2023
- Molecular Partners AG
- Hans Kaspar Binz
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Methods of administering a composition comprising a Tn3 scaffold an...
- Patent number 11,555,062
- Issue date Jan 17, 2023
- Viela Bio, Inc.
- Anthony Coyle
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
DPP3 binder directed to and binding to specific DPP3-epitopes and i...
- Patent number 11,530,276
- Issue date Dec 20, 2022
- 4TEEN4 Pharmaceuticals GmbH
- Andreas Bergmann
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Chimeric proteins
- Patent number 11,525,133
- Issue date Dec 13, 2022
- Cambridge Enterprise Limited
- Laura Itzhaki
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Cell surface conjugates and related cell compositions and methods
- Patent number 11,517,627
- Issue date Dec 6, 2022
- Juno Therapeutics GmbH
- Lothar Germeroth
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Multifunctional heteromultimeric constructs
- Patent number 11,518,791
- Issue date Dec 6, 2022
- Luxembourg Institute of Health (LIH)
- Xavier Dervillez
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Synthetic immunoglobulin domains with binding properties engineered...
- Patent number 11,499,249
- Issue date Nov 15, 2022
- F-star Therapeutics Limited
- Gottfried Himmler
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Method for generating high affinity, bivalent binding agents for sa...
- Patent number 11,473,080
- Issue date Oct 18, 2022
- The Board of Trustees of the University of Illinois
- Brian K. Kay
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antibody derivatives with conditionally enabled effector function
- Patent number 11,466,093
- Issue date Oct 11, 2022
- The General Hospital Corporation
- Glen S. Cho
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
PSMA-specific binding proteins
- Patent number 11,464,877
- Issue date Oct 11, 2022
- Arne Skerra
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bispecific T cell activating antigen binding molecules
- Patent number 11,459,404
- Issue date Oct 4, 2022
- Roche Glycart AG
- Marina Bacac
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods and composition for modifying enzymes
- Patent number 11,459,400
- Issue date Oct 4, 2022
- The University of Chicago
- Shohei Koide
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Insertable variable fragments of antibodies and modified A1-A2 doma...
- Patent number 11,453,713
- Issue date Sep 27, 2022
- Xyphos Biosciences Inc.
- Kyle Landgraf
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Designed ankyrin repeat proteins binding to hepatocyte growth factor
- Patent number 11,453,708
- Issue date Sep 27, 2022
- Molecular Partners AG
- Gaby Tresch
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
PD-L1 binding fibronectin type III domains
- Patent number 11,447,539
- Issue date Sep 20, 2022
- Janssen Biotech, Inc.
- Michael Diem
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Fibronectin based scaffold proteins
- Patent number 11,447,538
- Issue date Sep 20, 2022
- Bristol-Myers Squibb Company
- Dasa Lipovsek
- G01 - MEASURING TESTING
Information Patent Grant
Anti-thyroglobulin T cell receptors
- Patent number 11,440,956
- Issue date Sep 13, 2022
- The United States of America, as represented by the Secretary, Department of...
- Kenichi Hanada
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
PROTEIN-BASED CONJUGATION CARRIERS
- Publication number 20240415974
- Publication date Dec 19, 2024
- Ablynx N.V.
- Carlo Boutton
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
STABILIZED TCR CONSTRUCTS AND METHODS OF USE
- Publication number 20240409604
- Publication date Dec 12, 2024
- ZYMEWORKS BC INC.
- Eric ESCOBAR-CABRERA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CD40L-SPECIFIC TN3-DERIVED SCAFFOLDS FOR THE TREATMENT AND PREVENTI...
- Publication number 20240383991
- Publication date Nov 21, 2024
- Viela Bio, Inc.
- Ilias ALEVIZOS
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CD40L-SPECIFIC TN3-DERIVED SCAFFOLDS FOR USE IN THE TREATMENT AND P...
- Publication number 20240368294
- Publication date Nov 7, 2024
- Viela Bio, Inc.
- Gabor G. ILLEI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MCL-1 BINDING ALPHABODIES AND USES THEREOF
- Publication number 20240317807
- Publication date Sep 26, 2024
- COMPLIX NV
- Ignace LASTERS
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NOVEL DARPIN BASED CD33 ENGAGERS
- Publication number 20240317852
- Publication date Sep 26, 2024
- Molecular Partners AG
- Nina RESCHKE
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SCAFFOLD PROTEINS
- Publication number 20240317839
- Publication date Sep 26, 2024
- Avacta Life Sciences Limited
- Geoffrey William Platt
- C07 - ORGANIC CHEMISTRY
Information Patent Application
EPITOPE-SCAFFOLD IMMUNOGENS FOR PANCORONAVIRUS VACCINES
- Publication number 20240285753
- Publication date Aug 29, 2024
- DUKE UNIVERSITY
- Mihai Azoitei
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIGEN BINDING POLYPEPTIDES
- Publication number 20240239877
- Publication date Jul 18, 2024
- VIIV HEALTHCARE UK (NO.5) LIMITED
- Mark R. KRYSTAL
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND PCSK9
- Publication number 20240239870
- Publication date Jul 18, 2024
- Bristol-Myers Squibb Company
- Ray Camphausen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Antigen-Presenting Polypeptides with Chemical Conjugation Sites and...
- Publication number 20240189403
- Publication date Jun 13, 2024
- Cue Biopharma, Inc.
- Ronald D. SEIDEL
- C07 - ORGANIC CHEMISTRY
Information Patent Application
MULTl-CHAIN POLYPEPTIDE-CONTAINING TRI-SPECIFIC BINDING MOLECULES T...
- Publication number 20240182559
- Publication date Jun 6, 2024
- MacroGenics, Inc.
- Leslie S. JOHNSON
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ONCOLYTIC VIROTHERAPY WITH INDUCED ANTI-TUMOR IMMUNITY
- Publication number 20240150787
- Publication date May 9, 2024
- UNIVERSITY OF HOUSTON SYSTEM
- Shaun Xiaoliu ZHANG
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NEW HER2-BINDING POLYPEPTIDE
- Publication number 20240124533
- Publication date Apr 18, 2024
- AFFIBODY AB
- Fredrik FREJD
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TRI-SPECIFIC BINDING MOLECULES THAT SPECIFICALLY BIND TO MULTIPLE C...
- Publication number 20240117036
- Publication date Apr 11, 2024
- MacroGenics, Inc.
- Ezio BONVINI
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Heteromultivalent Nucleic Acid Scaffolds and Uses Thereof
- Publication number 20240084044
- Publication date Mar 14, 2024
- George Mason University
- Amanda Haymond Still
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RECOMBINANT CD3 BINDING PROTEINS AND THEIR USE
- Publication number 20240052033
- Publication date Feb 15, 2024
- Molecular Partners AG
- Sebastian GRIMM
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DE NOVO BINDING DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF
- Publication number 20240043550
- Publication date Feb 8, 2024
- SUBDOMAIN, LLC
- David William LAFLEUR
- C07 - ORGANIC CHEMISTRY
Information Patent Application
N-Terminal Capping Modules of Ankyrin Repeat Domains
- Publication number 20240043481
- Publication date Feb 8, 2024
- Athebio AG
- Patrik Forrer
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NPC1 MONOBODIES AND MONOBODY CONJUGATES THEREOF
- Publication number 20240025969
- Publication date Jan 25, 2024
- NEW YORK UNIVERSITY
- Craig RAMIREZ
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TESTOSTERONE-SPECIFIC AFFIBODY AND USES THEREOF
- Publication number 20240018233
- Publication date Jan 18, 2024
- INSSEN INC.
- Hye-Sun PARK
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTIBODY-LIKE PROTEIN AND USE THEREOF
- Publication number 20230391893
- Publication date Dec 7, 2023
- CELLEMEDY CO.,LTD
- Jee Won LEE
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTIMERIC PROTEIN COMPLEXES AS ANTIBODY SUBSTITUTES FOR NEUTRALIZA...
- Publication number 20230382977
- Publication date Nov 30, 2023
- The Regents of the University of California
- Daniel L. COX
- C07 - ORGANIC CHEMISTRY
Information Patent Application
LENTIVIRAL VECTORS ENABLING ROUTING ANTIGENS TO MHC-II PATHWAY AND...
- Publication number 20230364216
- Publication date Nov 16, 2023
- INSTITUT PASTEUR
- Pierre CHARNEAU
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED BINDING PROTEINS FOR RECOGNITION OF BACTERIA
- Publication number 20230358742
- Publication date Nov 9, 2023
- Massachusetts Institute of Technology
- Hadley Sikes Johnson
- G01 - MEASURING TESTING
Information Patent Application
SERUM STABLE BINDING PROTEINS FOR HUMAN HER2 FOR THERANOSTIC APPLIC...
- Publication number 20230322946
- Publication date Oct 12, 2023
- Navigo Proteins GmbH
- Eva Bosse-Doenecke
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Antibody Derivatives with Conditionally Enabled Effector Function
- Publication number 20230303709
- Publication date Sep 28, 2023
- The General Hospital Corporation
- Glen S. CHO
- C07 - ORGANIC CHEMISTRY
Information Patent Application
DPP3 BINDER DIRECTED TO AND BINDING TO SPECIFIC DPP3-EPITOPES AND I...
- Publication number 20230295344
- Publication date Sep 21, 2023
- 4TEEN4 PHARMACEUTICALS GMBH
- Andreas BERGMANN
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CELL SURFACE CONJUGATES AND RELATED CELL COMPOSITIONS AND METHODS
- Publication number 20230190952
- Publication date Jun 22, 2023
- Juno Therapeutics GmbH
- Lothar GERMEROTH
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Multifunctional Heteromultimeric Constructs
- Publication number 20230130737
- Publication date Apr 27, 2023
- Luxembourg Institute of Health (LIH)
- Xavier Dervillez
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Optimized variants of anti-VEGF antibodies

IL-IR-I binding polypeptide

Peptide for the delivery of anionic materials

Scaffold proteins

Switch molecule and switchable chimeric antigen receptor

Fibronectin based scaffold domain proteins that bind PCSK9

Serum albumin-binding fibronectin type III domains

Multi-chain polypeptide-containing tri-specific binding molecules

Citrate buffered VEGF antagonist formulations

Lipocalin muteins with binding affinity for LAG-3

Cysteine engineered fibronectin type III domain binding molecules

Tri-specific binding molecules that specifically bind to multiple c...

EGFR binding molecules

Designed ankyrin repeat domains with altered surface residues

Methods of administering a composition comprising a Tn3 scaffold an...

DPP3 binder directed to and binding to specific DPP3-epitopes and i...

Chimeric proteins

Cell surface conjugates and related cell compositions and methods

Multifunctional heteromultimeric constructs

Synthetic immunoglobulin domains with binding properties engineered...

Method for generating high affinity, bivalent binding agents for sa...

Antibody derivatives with conditionally enabled effector function

PSMA-specific binding proteins

Bispecific T cell activating antigen binding molecules

Methods and composition for modifying enzymes

Insertable variable fragments of antibodies and modified A1-A2 doma...

Designed ankyrin repeat proteins binding to hepatocyte growth factor

PD-L1 binding fibronectin type III domains

Fibronectin based scaffold proteins

Anti-thyroglobulin T cell receptors

Patents Applicationslast 30 patents

PROTEIN-BASED CONJUGATION CARRIERS

STABILIZED TCR CONSTRUCTS AND METHODS OF USE

CD40L-SPECIFIC TN3-DERIVED SCAFFOLDS FOR THE TREATMENT AND PREVENTI...

CD40L-SPECIFIC TN3-DERIVED SCAFFOLDS FOR USE IN THE TREATMENT AND P...

MCL-1 BINDING ALPHABODIES AND USES THEREOF

NOVEL DARPIN BASED CD33 ENGAGERS

SCAFFOLD PROTEINS

EPITOPE-SCAFFOLD IMMUNOGENS FOR PANCORONAVIRUS VACCINES

ANTIGEN BINDING POLYPEPTIDES

FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND PCSK9

Antigen-Presenting Polypeptides with Chemical Conjugation Sites and...

MULTl-CHAIN POLYPEPTIDE-CONTAINING TRI-SPECIFIC BINDING MOLECULES T...

ONCOLYTIC VIROTHERAPY WITH INDUCED ANTI-TUMOR IMMUNITY

NEW HER2-BINDING POLYPEPTIDE

TRI-SPECIFIC BINDING MOLECULES THAT SPECIFICALLY BIND TO MULTIPLE C...

Heteromultivalent Nucleic Acid Scaffolds and Uses Thereof

RECOMBINANT CD3 BINDING PROTEINS AND THEIR USE

DE NOVO BINDING DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF

N-Terminal Capping Modules of Ankyrin Repeat Domains

NPC1 MONOBODIES AND MONOBODY CONJUGATES THEREOF

TESTOSTERONE-SPECIFIC AFFIBODY AND USES THEREOF

ANTIBODY-LIKE PROTEIN AND USE THEREOF

MULTIMERIC PROTEIN COMPLEXES AS ANTIBODY SUBSTITUTES FOR NEUTRALIZA...

LENTIVIRAL VECTORS ENABLING ROUTING ANTIGENS TO MHC-II PATHWAY AND...

ENGINEERED BINDING PROTEINS FOR RECOGNITION OF BACTERIA

SERUM STABLE BINDING PROTEINS FOR HUMAN HER2 FOR THERANOSTIC APPLIC...

Antibody Derivatives with Conditionally Enabled Effector Function

DPP3 BINDER DIRECTED TO AND BINDING TO SPECIFIC DPP3-EPITOPES AND I...

CELL SURFACE CONJUGATES AND RELATED CELL COMPOSITIONS AND METHODS

Multifunctional Heteromultimeric Constructs