conjugates wherein the antibody being the modifying agent and wherein the linker, binder, spacer confers particular properties to the conjugate

Industry

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A61K47/48715

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AHUMAN NECESSITIES A61Medical science A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES A61K47/00Medicinal preparations characterised by the non-active ingredients used

Current Industry

A61K47/48715conjugates wherein the antibody being the modifying agent and wherein the linker, binder, spacer confers particular properties to the conjugate

Industries

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Patents Grantslast 30 patents

Information Patent Grant
Site-specific antibody-drug conjugation through glycoengineering
- Patent number 10,214,589
- Issue date Feb 26, 2019
- Genzyme Corporation
- Clark Pan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-HER2 antibody-drug conjugate
- Patent number 10,155,821
- Issue date Dec 18, 2018
- Daiichi Sankyo Company, Limited
- Hiroyuki Naito
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Liposomes for modulating Wiskott-Aldrich syndrome protein
- Patent number 10,154,962
- Issue date Dec 18, 2018
- Bar Ilan University
- Mira Barda-Saad
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-DLL3 antibody drug conjugates for treating cancer
- Patent number 10,137,204
- Issue date Nov 27, 2018
- ABBVIE STEMCENTRX LLC
- Robert A. Stull
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antibody-drug conjugates and uses thereof
- Patent number 10,130,718
- Issue date Nov 20, 2018
- Immunomedics, Inc.
- David M. Goldenberg
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Peptidomimetic compounds and antibody-drug conjugates thereof
- Patent number 10,124,069
- Issue date Nov 13, 2018
- Genentech, Inc.
- Ho Huat Lee
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Anti-HER2 antibody-drug conjugate
- Patent number 10,118,972
- Issue date Nov 6, 2018
- Daiichi Sankyo Company, Limited
- Hiroyuki Naito
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Weekly dosing regimens for anti-CD30 VC-PAB-MMAE antibody drug-conj...
- Patent number 10,098,963
- Issue date Oct 16, 2018
- Seattle Genetics, Inc.
- Eric Sievers
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Tubulysin analogs and methods of making and use
- Patent number 10,077,287
- Issue date Sep 18, 2018
- Bristol-Myers Squibb Company
- Heidi L. Perez
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Polypeptide complex comprising non-peptidyl polymer having three fu...
- Patent number 10,071,171
- Issue date Sep 11, 2018
- Hanmi Science Co., Ltd
- Dae Hae Song
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antibodies against the MUC1-C/extracellular domain (MUC1-C/ECD)
- Patent number 10,059,775
- Issue date Aug 28, 2018
- Dana-Farber Cancer Institute, Inc.
- Donald W. Kufe
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Lysosome-cleavable linker
- Patent number 10,010,623
- Issue date Jul 3, 2018
- UCL Business PLC
- Mark Edward Brennan Smith
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Peptidomimetic compounds and antibody-drug conjugates thereof
- Patent number 9,999,681
- Issue date Jun 19, 2018
- Genentech, Inc.
- John Flygare
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Isoquinolidinobenzodiazepines
- Patent number 9,974,864
- Issue date May 22, 2018
- Cellerant Therapeutics, Inc.
- Jagath R. Junutula
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibody-drug conjugates, their preparation and their therapeutic use
- Patent number 9,951,141
- Issue date Apr 24, 2018
- REGENERON PHARMACEUTICALS, INC.
- Thomas Nittoli
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Pyrrolobenzodiazepine-antibody conjugates
- Patent number 9,950,078
- Issue date Apr 24, 2018
- MedImmune Limited
- Philip Wilson Howard
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Hydrophilic self-immolative linkers and conjugates thereof
- Patent number 9,943,610
- Issue date Apr 17, 2018
- BioAlliance C.V.
- Rong-Hwa Lin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Murine, chimeric, humanized or human anti-IL-6 antibodies
- Patent number 9,932,413
- Issue date Apr 3, 2018
- IBC Pharmaceuticals, Inc.
- David M. Goldenberg
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-GPC3 antibodies and immunoconjugates
- Patent number 9,926,377
- Issue date Mar 27, 2018
- Genentech, Inc.
- Paul Polakis
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compounds comprising self-immolative group
- Patent number 9,919,057
- Issue date Mar 20, 2018
- Legochem Biosciences, Inc.
- Yong Zu Kim
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Macrocyclic benzodiazepine dimers, conjugates thereof, preparation...
- Patent number 9,902,740
- Issue date Feb 27, 2018
- Bristol-Myers Squibb Company
- Yong Zhang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of delivering DLL3 antibody drug conjugates
- Patent number 9,878,053
- Issue date Jan 30, 2018
- ABBVIE STEMCENTRX LLC
- Robert A. Stull
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibody-drug conjugate produced by binding through linker having h...
- Patent number 9,872,924
- Issue date Jan 23, 2018
- Daiichi Sankyo Company, Limited
- Hiroyuki Naito
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Complex in which anti-cotinine antibody is bound to conjugate of co...
- Patent number 9,867,886
- Issue date Jan 16, 2018
- SNU R&DB Foundation
- Junho Chung
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Kits containing DLL3 antibody drug conjugates
- Patent number 9,861,708
- Issue date Jan 9, 2018
- ABBVIE STEMCENTRX LLC
- Robert A. Stull
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-DLL3 antibody drug conjugates
- Patent number 9,855,343
- Issue date Jan 2, 2018
- ABBVIE STEMCENTRX LLC
- Robert A. Stull
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-TROP2 antibody-drug conjugate
- Patent number 9,850,312
- Issue date Dec 26, 2017
- Daiichi Sankyo Company, Limited
- Toshinori Agatsuma
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Acetylenedicarboxyl linkers and their uses in specific conjugation...
- Patent number 9,839,687
- Issue date Dec 12, 2017
- SUZHOU M-CONJ BIOTECH CO., LTD.
- Robert Yongxin Zhao
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Hydrazinyl-indole compounds and methods for producing a conjugate
- Patent number 9,833,515
- Issue date Dec 5, 2017
- REDWOOD BIOSCIENCE, INC.
- Romas Alvydas Kudirka
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-IL-13 receptor alpha 2 antibodies and antibody-drug conjugates
- Patent number 9,828,428
- Issue date Nov 28, 2017
- Pfizer Inc.
- Dangshe Ma
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
WEEKLY DOSING REGIMENS FOR ANTI-CD30 VC-PAB-MMAE ANTIBODY DRUG-CONJ...
- Publication number 20180369317
- Publication date Dec 27, 2018
- Seattle Genetics, Inc.
- Eric Sievers
- C07 - ORGANIC CHEMISTRY
Information Patent Application
HODGKIN LYMPHOMA THERAPY
- Publication number 20180098969
- Publication date Apr 12, 2018
- PURDUE PHARMACEUTICAL PRODUCTS L.P.
- Thomas Mehrling
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MATERIALS AND METHODS RELATING TO LINKERS FOR USE IN PROTEIN DRUG C...
- Publication number 20180092981
- Publication date Apr 5, 2018
- Glythera Limited
- Anthony David BAXTER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PYRROLOBENZODIAZEPINES AND TARGETED CONJUGATES
- Publication number 20170290924
- Publication date Oct 12, 2017
- Seattle Genetics, Inc.
- Scott Jeffrey
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Conjugates And Conjugating Reagents
- Publication number 20170290925
- Publication date Oct 12, 2017
- POLYTHERICS LIMITED
- Antony Godwin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
WEEKLY DOSING REGIMENS FOR ANTI-CD30 VC-PAB-MMAE ANTIBODY DRUG-CONJ...
- Publication number 20170281794
- Publication date Oct 5, 2017
- Seattle Genetics, Inc.
- Eric Sievers
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DLL3 MODULATORS AND METHODS OF USE
- Publication number 20170274094
- Publication date Sep 28, 2017
- AbbVie Stemcentrx LLC
- ROBERT A. STULL
- G01 - MEASURING TESTING
Information Patent Application
PRO-DRUG FORM (P2PDOX) OF THE HIGHLY POTENT 2-PYRROLINODOXORUBICIN...
- Publication number 20170266310
- Publication date Sep 21, 2017
- Immunomedics, Inc.
- Serengulam V. Govindan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS OF MAKING DLL3 ANTIBODY DRUG CONJUGATES
- Publication number 20170266314
- Publication date Sep 21, 2017
- AbbVie Stemcentrx LLC
- ROBERT A. STULL
- G01 - MEASURING TESTING
Information Patent Application
ANTI-DLL3 ANTIBODY DRUG CONJUGATES FOR TREATING CANCER
- Publication number 20170266315
- Publication date Sep 21, 2017
- AbbVie Stemcentrx LLC
- ROBERT A. STULL
- G01 - MEASURING TESTING
Information Patent Application
SITE-SPECIFIC ANTIBODY-DRUG CONJUGATION THROUGH GLYCOENGINEERING
- Publication number 20170267774
- Publication date Sep 21, 2017
- Genzyme Corporation
- Clark PAN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-DLL3 ANTIBODY DRUG CONJUGATES
- Publication number 20170266312
- Publication date Sep 21, 2017
- AbbVie Stemcentrx LLC
- ROBERT A. STULL
- G01 - MEASURING TESTING
Information Patent Application
METHODS OF DELIVERING DLL3 ANTIBODY DRUG CONJUGATES
- Publication number 20170266313
- Publication date Sep 21, 2017
- AbbVie Stemcentrx LLC
- ROBERT A. STULL
- G01 - MEASURING TESTING
Information Patent Application
Immunoconjugates with an Intracellularly-Cleavable Linkage
- Publication number 20170266316
- Publication date Sep 21, 2017
- Immunomedics, Inc.
- Serengulam V. Govindan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MACROCYCLIC BENZODIAZEPINE DIMERS, CONJUGATES THEREOF, PREPARATION...
- Publication number 20170260205
- Publication date Sep 14, 2017
- Bristol-Myers Squibb Company
- Yong ZHANG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES
- Publication number 20170258934
- Publication date Sep 14, 2017
- ADC THERAPEUTICS SA
- Patricius Henrikus Cornelis VAN BERKEL
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Tunable pH-Sensitive Linker for Controlled Drug Release
- Publication number 20170258936
- Publication date Sep 14, 2017
- Washington State University
- Clifford E. Berkman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CYSTEINE ENGINEERED ANTIBODIES AND CONJUGATES
- Publication number 20170260253
- Publication date Sep 14, 2017
- Genentech, Inc.
- Sunil Bhakta
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOUNDS AND METHODS FOR THE TREATMENT OF ERB B2/NEU POSITIVE DISE...
- Publication number 20170258935
- Publication date Sep 14, 2017
- BIO-THERA SOLUTIONS, LTD., CO.
- Weijia Tang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Immunoconjugates with an Intracellularly-Cleavable Linkage
- Publication number 20170239368
- Publication date Aug 24, 2017
- Immunomedics, Inc.
- Serengulam V. Govindan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
QUATERNARY AMINE COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF
- Publication number 20170232113
- Publication date Aug 17, 2017
- Genentech, Inc.
- John A. Flygare
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BCMA ANTIBODIES AND USE OF SAME TO TREAT CANCER AND IMMUNOLOGICAL D...
- Publication number 20170233484
- Publication date Aug 17, 2017
- Seattle Genetics, Inc.
- Django Sussman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MATERIALS AND METHODS RELATING TO LINKERS FOR USE IN PROTEIN DRUG C...
- Publication number 20170232108
- Publication date Aug 17, 2017
- Glythera Limited
- Anthony David BAXTER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHOD OF TARGETING SPECIFIC CELL POPULATIONS USING CELL-BINDING AG...
- Publication number 20170226220
- Publication date Aug 10, 2017
- ImmunoGen, Inc.
- Ravi V.J. CHARI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
HYDROPHILIC ANTIBODY-DRUG CONJUGATES
- Publication number 20170216391
- Publication date Aug 3, 2017
- Seattle Genetics, Inc.
- Svetlana Doronina
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SITE-SPECIFIC LABELING METHODS AND MOLECULES PRODUCED THEREBY
- Publication number 20170218085
- Publication date Aug 3, 2017
- Novartis AG
- Bernhard Hubert GEIERSTANGER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE
- Publication number 20170209595
- Publication date Jul 27, 2017
- SUZHOU M-CONJ BIOTECH CO., LTD
- Robert Yongxin Zhao
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS OF CONJUGATING AN AGENT TO A THIOL MOIETY IN A PROTEIN THAT...
- Publication number 20170209593
- Publication date Jul 27, 2017
- Genentech, Inc.
- Jayme FRANKLIN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MATRIPTASE AND U-PLASMINOGEN ACTIVATOR SUBSTRATES AND OTHER CLEAVAB...
- Publication number 20170204139
- Publication date Jul 20, 2017
- CytomX Therapeutics, Inc.
- Stephen James Moore
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS OF TREATING METASTATIC BREAST CANCER WITH TRASTUZUMAB-MCC-DM1
- Publication number 20170202973
- Publication date Jul 20, 2017
- Genentech, Inc.
- Samuel Agresta
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

conjugates wherein the antibody being the modifying agent and wherein the linker, binder, spacer confers particular properties to the conjugate

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Site-specific antibody-drug conjugation through glycoengineering

Anti-HER2 antibody-drug conjugate

Liposomes for modulating Wiskott-Aldrich syndrome protein

Anti-DLL3 antibody drug conjugates for treating cancer

Antibody-drug conjugates and uses thereof

Peptidomimetic compounds and antibody-drug conjugates thereof

Anti-HER2 antibody-drug conjugate

Weekly dosing regimens for anti-CD30 VC-PAB-MMAE antibody drug-conj...

Tubulysin analogs and methods of making and use

Polypeptide complex comprising non-peptidyl polymer having three fu...

Antibodies against the MUC1-C/extracellular domain (MUC1-C/ECD)

Lysosome-cleavable linker

Peptidomimetic compounds and antibody-drug conjugates thereof

Isoquinolidinobenzodiazepines

Antibody-drug conjugates, their preparation and their therapeutic use

Pyrrolobenzodiazepine-antibody conjugates

Hydrophilic self-immolative linkers and conjugates thereof

Murine, chimeric, humanized or human anti-IL-6 antibodies

Anti-GPC3 antibodies and immunoconjugates

Compounds comprising self-immolative group

Macrocyclic benzodiazepine dimers, conjugates thereof, preparation...

Methods of delivering DLL3 antibody drug conjugates

Antibody-drug conjugate produced by binding through linker having h...

Complex in which anti-cotinine antibody is bound to conjugate of co...

Kits containing DLL3 antibody drug conjugates

Anti-DLL3 antibody drug conjugates

Anti-TROP2 antibody-drug conjugate

Acetylenedicarboxyl linkers and their uses in specific conjugation...

Hydrazinyl-indole compounds and methods for producing a conjugate

Anti-IL-13 receptor alpha 2 antibodies and antibody-drug conjugates

Patents Applicationslast 30 patents

WEEKLY DOSING REGIMENS FOR ANTI-CD30 VC-PAB-MMAE ANTIBODY DRUG-CONJ...

HODGKIN LYMPHOMA THERAPY

MATERIALS AND METHODS RELATING TO LINKERS FOR USE IN PROTEIN DRUG C...

PYRROLOBENZODIAZEPINES AND TARGETED CONJUGATES

Conjugates And Conjugating Reagents

WEEKLY DOSING REGIMENS FOR ANTI-CD30 VC-PAB-MMAE ANTIBODY DRUG-CONJ...

DLL3 MODULATORS AND METHODS OF USE

PRO-DRUG FORM (P2PDOX) OF THE HIGHLY POTENT 2-PYRROLINODOXORUBICIN...

METHODS OF MAKING DLL3 ANTIBODY DRUG CONJUGATES

ANTI-DLL3 ANTIBODY DRUG CONJUGATES FOR TREATING CANCER

SITE-SPECIFIC ANTIBODY-DRUG CONJUGATION THROUGH GLYCOENGINEERING

ANTI-DLL3 ANTIBODY DRUG CONJUGATES

METHODS OF DELIVERING DLL3 ANTIBODY DRUG CONJUGATES

Immunoconjugates with an Intracellularly-Cleavable Linkage

MACROCYCLIC BENZODIAZEPINE DIMERS, CONJUGATES THEREOF, PREPARATION...

PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES

Tunable pH-Sensitive Linker for Controlled Drug Release

CYSTEINE ENGINEERED ANTIBODIES AND CONJUGATES

COMPOUNDS AND METHODS FOR THE TREATMENT OF ERB B2/NEU POSITIVE DISE...

Immunoconjugates with an Intracellularly-Cleavable Linkage

QUATERNARY AMINE COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF

BCMA ANTIBODIES AND USE OF SAME TO TREAT CANCER AND IMMUNOLOGICAL D...

MATERIALS AND METHODS RELATING TO LINKERS FOR USE IN PROTEIN DRUG C...

METHOD OF TARGETING SPECIFIC CELL POPULATIONS USING CELL-BINDING AG...

HYDROPHILIC ANTIBODY-DRUG CONJUGATES

SITE-SPECIFIC LABELING METHODS AND MOLECULES PRODUCED THEREBY

DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE

METHODS OF CONJUGATING AN AGENT TO A THIOL MOIETY IN A PROTEIN THAT...

MATRIPTASE AND U-PLASMINOGEN ACTIVATOR SUBSTRATES AND OTHER CLEAVAB...

METHODS OF TREATING METASTATIC BREAST CANCER WITH TRASTUZUMAB-MCC-DM1