Directed molecular evolution of macromolecules

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CPC
C40B10/00

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CCHEMISTRY METALLURGY C40Combinatorial chemistry C40BCOMBINATORIAL CHEMISTRY LIBRARIES

Current Industry

C40B10/00Directed molecular evolution of macromolecules

Industries

Patents Grantslast 30 patents

Information Patent Grant
Determination of JAK-STAT3 pathway activity using unique combinatio...
- Patent number 12,125,561
- Issue date Oct 22, 2024
- InnoSIGN B.V.
- Meng Dou
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
High-throughput immune sequencing
- Patent number 12,012,670
- Issue date Jun 18, 2024
- President and Fellows of Harvard College
- George M. Church
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Mammalian cell line for protein production and library generation
- Patent number 11,802,281
- Issue date Oct 31, 2023
- ETH ZURICH
- Sai Reddy
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Method for producing RNA molecule compositions
- Patent number 11,684,665
- Issue date Jun 27, 2023
- CureVac SE
- Tilmann Roos
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Computer assisted antibody re-epitoping
- Patent number 11,468,969
- Issue date Oct 11, 2022
- Biolojic Design Ltd.
- Yanay Ofran
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Method of improving characteristics of proteins
- Patent number 11,332,735
- Issue date May 17, 2022
- Full Spectrum Genetics, Inc.
- Robert DuBridge
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Compositions, methods and systems for identifying candidate nucleic...
- Patent number 11,248,231
- Issue date Feb 15, 2022
- Aptitude Medical Systems, Inc.
- Jinpeng Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oligonucleotide directed and recorded combinatorial synthesis of en...
- Patent number 11,186,836
- Issue date Nov 30, 2021
- Haystack Sciences Corporation
- Richard Edward Watts
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Directed evolution through mutation rate modulation
- Patent number 11,072,790
- Issue date Jul 27, 2021
- Peter B. Reintjes
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Functional ligands to LL37
- Patent number 10,927,381
- Issue date Feb 23, 2021
- Base Pair Biotechnologies, Inc.
- George W. Jackson
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Antibody like protein
- Patent number 10,870,926
- Issue date Dec 22, 2020
- IDEA ORCHARD, LLC
- Michael Longo
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
System for continuous mutagenesis in vivo to facilitate directed ev...
- Patent number 10,760,071
- Issue date Sep 1, 2020
- The Regents of the University of California
- Manel Camps
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Method of improving characteristics of proteins
- Patent number 10,526,597
- Issue date Jan 7, 2020
- Full Spectrum Genetics, Inc.
- Robert DuBridge
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Methods for making and using polynucleotide sequences in the synthe...
- Patent number 10,487,345
- Issue date Nov 26, 2019
- Epimeron Inc.
- Peter James Facchini
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
High-throughput immune sequencing
- Patent number 10,392,726
- Issue date Aug 27, 2019
- President and Fellows of Harvard College
- George M. Church
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Molecules
- Patent number 10,381,110
- Issue date Aug 13, 2019
- University of Dundee
- Andrew Lee Hopkins
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Antibody like protein
- Patent number 10,370,776
- Issue date Aug 6, 2019
- IDEA ORCHARD, LLC
- Michael Longo
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Negative selection and stringency modulation in continuous evolutio...
- Patent number 10,179,911
- Issue date Jan 15, 2019
- President and Fellows of Harvard College
- David R. Liu
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Methods and compositions for identifying a peptide having an interm...
- Patent number 10,160,967
- Issue date Dec 25, 2018
- AEBi Ltd.
- Ilan Morad
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Generation of library of soluble random polypeptides linked to mRNA
- Patent number 9,920,453
- Issue date Mar 20, 2018
- ProteoNova, Inc.
- Richard B Williams
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Cell surface display, screening and production of proteins of interest
- Patent number 9,645,146
- Issue date May 9, 2017
- Agenus, Inc.
- James A. Rakestraw
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Structure-activity relationships
- Patent number 9,228,223
- Issue date Jan 5, 2016
- Codexis, Inc.
- Emily Mundorff
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Generation of library of soluble random polypeptides linked to mRNA
- Patent number 9,080,256
- Issue date Jul 14, 2015
- ProteoNova, Inc.
- Richard B Williams
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Cell surface display, screening and production of proteins of interest
- Patent number 8,722,586
- Issue date May 13, 2014
- Celexion, LLC
- James A. Rakestraw
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Genetic selection for protein folding and solubility in the bacteri...
- Patent number 8,722,584
- Issue date May 13, 2014
- Cornell University
- Matthew P. Delisa
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Cell surface display, screening and production of proteins of interest
- Patent number 8,709,980
- Issue date Apr 29, 2014
- Celexion, LLC
- James A. Rakestraw
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Evolved orthogonal ribosomes
- Patent number 8,497,231
- Issue date Jul 30, 2013
- Medical Research Council
- Jason Chin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Micro-organisms for the production of 1,2-propanediol obtained by a...
- Patent number 8,298,807
- Issue date Oct 30, 2012
- Metabolic Explorer
- Philippe Soucaille
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method for obtaining new life forms
- Patent number 7,960,103
- Issue date Jun 14, 2011
- Institut Pasteur
- Rupert Mutzel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Directed evolution of recombinant monooxygenase nucleic acids and r...
- Patent number 7,723,498
- Issue date May 25, 2010
- University of Connecticut
- Thomas K. Wood
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
ACTIVATABLE ANTIBODIES AND METHODS OF MAKING AND USING THEREOF
- Publication number 20240150749
- Publication date May 9, 2024
- ADAGENE INC.
- Peter Peizhi LUO
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
MAMMALIAN CELL LINE FOR PROTEIN PRODUCTION AND LIBRARY GENERATION
- Publication number 20230374491
- Publication date Nov 23, 2023
- ETH ZURICH
- Sai REDDY
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MACHINE GUIDED DIRECTED EVOLUTION OF RAAV COMBINATORIAL CAPSID LIBR...
- Publication number 20230203533
- Publication date Jun 29, 2023
- University of Florida Research Foundation, Incorporated
- Sergei Zolotukhin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPUTER ASSISTED ANTIBODY RE-EPITOPING
- Publication number 20220415436
- Publication date Dec 29, 2022
- Biolojic Design Ltd.
- Yanay OFRAN
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
OLIGONUCLEOTIDE DIRECTED AND RECORDED COMBINITORIAL SYNTHESIS OF EN...
- Publication number 20220154179
- Publication date May 19, 2022
- Haystack Sciences Corporation
- Richard Edward WATTS
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
Methods For Making and Using Polynucleotide Sequences in the Synthe...
- Publication number 20210198706
- Publication date Jul 1, 2021
- EPIMERON INC.
- Peter James Facchini
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
FUNCTIONAL LIGANDS TO LL37
- Publication number 20200172906
- Publication date Jun 4, 2020
- BASE PAIR BIOTECHNOLOGIES, INC.
- George W. Jackson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
High-Throughput Immune Sequencing
- Publication number 20200095704
- Publication date Mar 26, 2020
- President and Fellows of Harvard College
- George M. Church
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DESIGN OF MOLECULES
- Publication number 20200013486
- Publication date Jan 9, 2020
- UNIVERSITY OF DUNDEE
- Andrew Lee Hopkins
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
NOVEL ENGINEERED AND CHIMERIC NUCLEASES
- Publication number 20190359976
- Publication date Nov 28, 2019
- The Regents of the University of Colorado, a Body Corporate
- Ryan T. GILL
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTIBODY LIKE PROTEIN
- Publication number 20190316275
- Publication date Oct 17, 2019
- Idea Orchard, LLC
- Michael Longo
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NEGATIVE SELECTION AND STRINGENCY MODULATION IN CONTINUOUS EVOLUTIO...
- Publication number 20190256842
- Publication date Aug 22, 2019
- President and Fellows of Harvard College
- David R. Liu
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
PRECISION/CONTEXT-DEPENDENT ACTIVATABLE ANTIBODIES, AND METHODS OF...
- Publication number 20190241886
- Publication date Aug 8, 2019
- ADAGENE INC.
- Fangyong Du
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS, METHODS AND SYSTEMS FOR IDENTIFYING CANDIDATE NUCLEIC...
- Publication number 20190211335
- Publication date Jul 11, 2019
- Aptitude Medical Systems, Inc.
- Jinpeng Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD OF IMPROVING CHARACTERISTICS OF PROTEINS
- Publication number 20190078081
- Publication date Mar 14, 2019
- Robert DuBridge
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GENERATION OF LIBRARY OF SOLUBLE RANDOM POLYPEPTIDES LINKED TO mRNA
- Publication number 20180334760
- Publication date Nov 22, 2018
- PROTEONOVA, INC.
- Richard B. Williams
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
SYSTEM FOR CONTINUOUS MUTAGENESIS IN VIVO TO FACILITATE DIRECTED EV...
- Publication number 20180216097
- Publication date Aug 2, 2018
- The Regents of the University of California
- Manel CAMPS
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
DIRECTED EVOLUTION THROUGH MUTATION RATE MODULATION
- Publication number 20180187182
- Publication date Jul 5, 2018
- Peter B. Reintjes
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPUTER ASSISTED ANTIBODY RE-EPITOPING
- Publication number 20180068055
- Publication date Mar 8, 2018
- Yanay OFRAN
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
Cell Surface Display, Screening and Production of Proteins of Interest
- Publication number 20170261506
- Publication date Sep 14, 2017
- Agenus Inc.
- James A. Rakestraw
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
DESIGN OF MOLECULES
- Publication number 20160196412
- Publication date Jul 7, 2016
- UNIVERSITY OF DUNDEE
- Andrew Lee Hopkins
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
Cell Surface Display, Screening and Production of Proteins of Interest
- Publication number 20140357508
- Publication date Dec 4, 2014
- James A. Rakestraw
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
STRUCTURE-ACTIVITY RELATIONSHIPS
- Publication number 20130165341
- Publication date Jun 27, 2013
- Codexis, Inc.
- Emily Mundorff
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
DESIGN OF MOLECULES
- Publication number 20120265514
- Publication date Oct 18, 2012
- Andrew Lee Hopkins
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
METHOD FOR AN IN VITRO MOLECULAR EVOLUTION OF ANTIBODY FUNCTION
- Publication number 20120077710
- Publication date Mar 29, 2012
- BIOINVENT INTERNATIONAL AB
- Mats Ohlin
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
NEW MICRO-ORGANISMS FOR THE PRODUCTION OF 1,2-PROPANEDIOL OBTAINED...
- Publication number 20100285547
- Publication date Nov 11, 2010
- Metalbolic Explorer
- Philippe Soucaille
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
Cell Surface Display, Screening and Production of Proteins of Interest
- Publication number 20100267057
- Publication date Oct 21, 2010
- James A. Rakestraw
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
METHODS FOR CARRYING OUT THE SELECTIVE EVOLUTION OF PROTEINS IN VIVO
- Publication number 20100151517
- Publication date Jun 17, 2010
- GENEART AG
- Michael Liss
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
GENETIC SELECTION FOR PROTEIN FOLDING AND SOLUBILITY IN THE BACTERI...
- Publication number 20100144546
- Publication date Jun 10, 2010
- Cornell University
- Matthew P. Delisa
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
GENERATION OF LIBRARY OF SOLUBLE RANDOM POLYPEPTIDES LINKED TO mRNA
- Publication number 20100113302
- Publication date May 6, 2010
- PROTEONOVA, INC.
- Richard B Williams
- C40 - COMBINATORIAL CHEMISTRY

Directed molecular evolution of macromolecules

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Determination of JAK-STAT3 pathway activity using unique combinatio...

High-throughput immune sequencing

Mammalian cell line for protein production and library generation

Method for producing RNA molecule compositions

Computer assisted antibody re-epitoping

Method of improving characteristics of proteins

Compositions, methods and systems for identifying candidate nucleic...

Oligonucleotide directed and recorded combinatorial synthesis of en...

Directed evolution through mutation rate modulation

Functional ligands to LL37

Antibody like protein

System for continuous mutagenesis in vivo to facilitate directed ev...

Method of improving characteristics of proteins

Methods for making and using polynucleotide sequences in the synthe...

High-throughput immune sequencing

Molecules

Antibody like protein

Negative selection and stringency modulation in continuous evolutio...

Methods and compositions for identifying a peptide having an interm...

Generation of library of soluble random polypeptides linked to mRNA

Cell surface display, screening and production of proteins of interest

Structure-activity relationships

Generation of library of soluble random polypeptides linked to mRNA

Cell surface display, screening and production of proteins of interest

Genetic selection for protein folding and solubility in the bacteri...

Cell surface display, screening and production of proteins of interest

Evolved orthogonal ribosomes

Micro-organisms for the production of 1,2-propanediol obtained by a...

Method for obtaining new life forms

Directed evolution of recombinant monooxygenase nucleic acids and r...

Patents Applicationslast 30 patents

ACTIVATABLE ANTIBODIES AND METHODS OF MAKING AND USING THEREOF

MAMMALIAN CELL LINE FOR PROTEIN PRODUCTION AND LIBRARY GENERATION

MACHINE GUIDED DIRECTED EVOLUTION OF RAAV COMBINATORIAL CAPSID LIBR...

COMPUTER ASSISTED ANTIBODY RE-EPITOPING

OLIGONUCLEOTIDE DIRECTED AND RECORDED COMBINITORIAL SYNTHESIS OF EN...

Methods For Making and Using Polynucleotide Sequences in the Synthe...

FUNCTIONAL LIGANDS TO LL37

High-Throughput Immune Sequencing

DESIGN OF MOLECULES

NOVEL ENGINEERED AND CHIMERIC NUCLEASES

ANTIBODY LIKE PROTEIN

NEGATIVE SELECTION AND STRINGENCY MODULATION IN CONTINUOUS EVOLUTIO...

PRECISION/CONTEXT-DEPENDENT ACTIVATABLE ANTIBODIES, AND METHODS OF...

COMPOSITIONS, METHODS AND SYSTEMS FOR IDENTIFYING CANDIDATE NUCLEIC...

METHOD OF IMPROVING CHARACTERISTICS OF PROTEINS

GENERATION OF LIBRARY OF SOLUBLE RANDOM POLYPEPTIDES LINKED TO mRNA

SYSTEM FOR CONTINUOUS MUTAGENESIS IN VIVO TO FACILITATE DIRECTED EV...

DIRECTED EVOLUTION THROUGH MUTATION RATE MODULATION

COMPUTER ASSISTED ANTIBODY RE-EPITOPING

Cell Surface Display, Screening and Production of Proteins of Interest

DESIGN OF MOLECULES

Cell Surface Display, Screening and Production of Proteins of Interest

STRUCTURE-ACTIVITY RELATIONSHIPS

DESIGN OF MOLECULES

METHOD FOR AN IN VITRO MOLECULAR EVOLUTION OF ANTIBODY FUNCTION

NEW MICRO-ORGANISMS FOR THE PRODUCTION OF 1,2-PROPANEDIOL OBTAINED...

Cell Surface Display, Screening and Production of Proteins of Interest

METHODS FOR CARRYING OUT THE SELECTIVE EVOLUTION OF PROTEINS IN VIVO

GENETIC SELECTION FOR PROTEIN FOLDING AND SOLUBILITY IN THE BACTERI...

GENERATION OF LIBRARY OF SOLUBLE RANDOM POLYPEPTIDES LINKED TO mRNA