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due to mutation of coding region of the transgene (dominant negative)
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A01K2217/056
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ANIMAL HUSBANDRY CARE OF BIRDS, FISHES, INSECTS FISHING REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR NEW BREEDS OF ANIMALS
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Genetically modified animals
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A01K2217/056
due to mutation of coding region of the transgene (dominant negative)
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last 30 patents
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Patent Grant
Genetically modified mouse expressing human APOE4 and mouse Trem2 p...
Patent number
11,957,115
Issue date
Apr 16, 2024
The Jackson Laboratory
Gareth Howell
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Genetically modified rat models for severe combined immunodeficienc...
Patent number
11,849,709
Issue date
Dec 26, 2023
Hera Testing Laboratories, Inc.
Eric M. Ostertag
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Crnn loss of function rodent model
Patent number
11,825,819
Issue date
Nov 28, 2023
REGENERON PHARMACEUTICALS, INC.
Claudia Gonzaga-Jauregui
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Mutations in rhodopsin gene in zebrafish and uses thereof
Patent number
11,746,391
Issue date
Sep 5, 2023
The Florida State University Research Foundation, Inc.
James Fadool
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Fibrillin-1 mutations for modeling neonatal progeroid syndrome with...
Patent number
11,730,150
Issue date
Aug 22, 2023
REGENERON PHARMACEUTICALS, INC.
Charleen Hunt
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Methods and compositions for modulating gene expression
Patent number
11,624,065
Issue date
Apr 11, 2023
Flagship Pioneering Innovations V, Inc.
Laura Gabriela Lande
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Recombinant adenovirus-based interferon biotherapeutics in swine
Patent number
11,582,956
Issue date
Feb 21, 2023
The United States of America, as represented by the Secretary of Agriculture
James J. Zhu
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Method of preparing ddx27-deletion zebrafish mutants
Patent number
11,406,090
Issue date
Aug 9, 2022
Shanghai Ocean University
Qinghua Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for modulating gene expression
Patent number
11,312,955
Issue date
Apr 26, 2022
Flagship Pioneering Innovations V, Inc.
David Arthur Berry
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for characterizing a microbiome
Patent number
11,284,609
Issue date
Mar 29, 2022
MarvelBiome, Inc.
Jothi Amaranath Govindan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Atopic dermatitis model non-human animal and use thereof
Patent number
11,213,020
Issue date
Jan 4, 2022
Kyushu University, National University Corporation
Yoshinori Fukui
G01 - MEASURING TESTING
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Patent Grant
Parkinson's disease model and methods
Patent number
11,122,784
Issue date
Sep 21, 2021
Boston Medical Center Corporation
Victoria Bolotina
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Grant
Genetically modified rat models for severe combined immunodeficienc...
Patent number
11,089,765
Issue date
Aug 17, 2021
Hera Testing Laboratories, Inc.
Eric M. Ostertag
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Application of GPR45 gene
Patent number
10,953,109
Issue date
Mar 23, 2021
Xiaohui Wu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Therapeutic agent for sarcopenia and metabolic diseases
Patent number
10,913,949
Issue date
Feb 9, 2021
Nagasaki University
Yusuke Ono
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Mutations in rhodopsin gene in zebrafish and uses thereof
Patent number
10,907,220
Issue date
Feb 2, 2021
The Florida State University Research Foundation Inc.
James Fadool
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Generation and correction of a humanized mouse model with a deletio...
Patent number
10,687,520
Issue date
Jun 23, 2020
The Board of Regents of the University of Texas System
Yi-Li Min
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Fibrillin-1 mutations for modeling neonatal progeroid syndrome with...
Patent number
10,548,302
Issue date
Feb 4, 2020
REGENERON PHARMACEUTICALS, INC.
Charleen Hunt
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Parkinsons disease model and methods
Patent number
10,390,521
Issue date
Aug 27, 2019
Boston Medical Center Corporation
Victoria Bolotina
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
SorCS1 for the treatment of obesity
Patent number
10,172,918
Issue date
Jan 8, 2019
Aarhus Universitet
Karen-Marie Pedersen
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Genetically modified non-human animals and methods relating to inna...
Patent number
10,021,861
Issue date
Jul 17, 2018
The Jackson Laboratory
Leonard D. Shultz
G01 - MEASURING TESTING
Information
Patent Grant
Transgenic pig models of cystic fibrosis
Patent number
10,004,212
Issue date
Jun 26, 2018
University of Iowa Research Foundation
Michael J. Welsh
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Screen and use of therapeutics for pancreatic ductal adenocarcinoma
Patent number
9,986,723
Issue date
Jun 5, 2018
The Board of Regents of the University of Texas System
Thomas M. Wilkie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
SorCS1-like agent for use in the treatment of insulin resistance an...
Patent number
9,931,374
Issue date
Apr 3, 2018
Aarhus Universitet
Karen-Marie Pedersen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Method for treating arthritis using IK factor or nucleic acid encod...
Patent number
9,737,588
Issue date
Aug 22, 2017
CELLINBIO CO., LTD
Jae-Hwan Nam
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Transgenic pig models of cystic fibrosis
Patent number
9,661,831
Issue date
May 30, 2017
University of Iowa Research Foundation
Michael J. Welsh
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Animal models of neurological disorders
Patent number
9,491,935
Issue date
Nov 15, 2016
Ann & Robert H. Lurie Children's Hospital of Chicago
Jhumku Kohtz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Genetically modified non-human animals and methods relating to inna...
Patent number
9,414,576
Issue date
Aug 16, 2016
The Jackson Laboratory
Leonard D. Shultz
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
RbAp48 transgenic mice for drug discovery in age-related memory dec...
Patent number
9,387,263
Issue date
Jul 12, 2016
The Trustees of Columbia University In the City of New York
Scott A. Small
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
SorCS1 for the treatment of obesity
Patent number
9,387,232
Issue date
Jul 12, 2016
Aarhus Universitet
Karen-Marie Pedersen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Patents Applications
last 30 patents
Information
Patent Application
GENETICALLY MODIFIED MOUSE EXPRESSING HUMAN APOE4 AND MOUSE TREM2 P...
Publication number
20240315220
Publication date
Sep 26, 2024
The Jackson Laboratory
Gareth Howell
G01 - MEASURING TESTING
Information
Patent Application
IMMUNOTHERAPY COMPOSITIONS AND METHODS FOR TREATMENT OF TAUOPATHY A...
Publication number
20240299512
Publication date
Sep 12, 2024
UNM Rainforest Innovations
Kiran Bhaskar
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
IMMUNOTHERAPY COMPOSITIONS AND METHODS FOR TREATMENT OF TAUOPATHY A...
Publication number
20240197845
Publication date
Jun 20, 2024
UNM Rainforest Innovations
Kiran Bhaskar
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
GENETICALLY MODIFIED RAT MODELS FOR SEVERE COMBINED IMMUNODEFICIENC...
Publication number
20240156069
Publication date
May 16, 2024
Hera Testing Laboratories, Inc.
Eric M. OSTERTAG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
A HIGH-THROUGHPUT SCREENING METHOD TO DISCOVER OPTIMAL GRNA PAIRS F...
Publication number
20230349888
Publication date
Nov 2, 2023
DUKE UNIVERSITY
Charles A. Gersbach
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
MODEL ORGANISMS HUMANIZED FOR DRUG DISCOVERY AND SCREENING
Publication number
20230200362
Publication date
Jun 29, 2023
NemaMetrix, Inc
Trisha J. Brock
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
ENGINEERED CELLS, ANIMAL MODELS, AND USES THEREOF FOR MODELING LOW...
Publication number
20230189773
Publication date
Jun 22, 2023
Washington University
David Gutmann
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION
Publication number
20230174978
Publication date
Jun 8, 2023
FLAGSHIP PIONEERING INNOVATIONS V, INC.
David Arthur Berry
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION
Publication number
20230054672
Publication date
Feb 23, 2023
FLAGSHIP PIONEERING INNOVATIONS V, INC.
David Arthur Berry
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
COMPOSITIONS AND METHODS FOR THE TREATMENT OF LEUKODYSTROPHY AND WH...
Publication number
20220265862
Publication date
Aug 25, 2022
The Children's Hospital of Philadelphia
Akshata Almad
G01 - MEASURING TESTING
Information
Patent Application
COMPOSITIONS AND METHODS FOR CHARACTERIZING A MICROBIOME
Publication number
20220256823
Publication date
Aug 18, 2022
MarvelBiome, Inc.
Jothi Amaranath Govindan
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
GENETICALLY MODIFIED RAT MODELS FOR SEVERE COMBINED IMMUNODEFICIENC...
Publication number
20220167598
Publication date
Jun 2, 2022
Hera Testing Laboratories, Inc.
Eric M. OSTERTAG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENETICALLY MODIFIED RAT MODELS FOR SEVERE COMBINED IMMUNODEFICIENC...
Publication number
20210392864
Publication date
Dec 23, 2021
Hera Testing Laboratories, Inc.
Eric M. OSTERTAG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ATOPIC DERMATITIS MODEL NON-HUMAN ANIMAL AND USE THEREOF
Publication number
20210337777
Publication date
Nov 4, 2021
Kyushu University, National University Corporation
Yoshinori FUKUI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHOD FOR PREPARING ALZHEIMER'S DISEASE (AD) ANIMAL MODEL
Publication number
20210329894
Publication date
Oct 28, 2021
Shanxi Medical University
Qiao NIU
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
CRNN LOSS OF FUNCTION RODENT MODEL
Publication number
20210100227
Publication date
Apr 8, 2021
Regeneron Pharmaceuticals, Inc.
Claudia GONZAGA-JAUREGUI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOSITIONS AND METHODS FOR CHARACTERIZING A MICROBIOME
Publication number
20210076649
Publication date
Mar 18, 2021
MarvelBiome, Inc.
Jothi Amaranath Govindan
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
ADAM6 KNOCKIN MICE
Publication number
20210059229
Publication date
Mar 4, 2021
TRIANNI, INC.
Gloria ESPOSITO
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
MUTATIONS IN RHODOPSIN GENE IN ZEBRAFISH AND USES THEREOF
Publication number
20210032709
Publication date
Feb 4, 2021
The Florida State University Research Foundation Inc.
James Fadool
G01 - MEASURING TESTING
Information
Patent Application
FIBRILLIN-1 MUTATIONS FOR MODELING NEONATAL PROGEROID SYNDROME WITH...
Publication number
20200107527
Publication date
Apr 9, 2020
Regeneron Pharmaceuticals, Inc.
Charleen Hunt
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
METHOD OF PREPARING ddx27-DELETION ZEBRAFISH MUTANTS
Publication number
20200053990
Publication date
Feb 20, 2020
Shanghai Ocean University
Qinghua ZHANG
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
A GENETICALLY MODIFIED MOUSE EXPRESSING HUMAN APOE4 AND MOUSE TREM2...
Publication number
20200022343
Publication date
Jan 23, 2020
The Jackson Laboratory
Gareth Howell
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
APPLICATION OF GPR45 GENE
Publication number
20190343969
Publication date
Nov 14, 2019
Fudan University
XIAOHUI WU
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION
Publication number
20190255106
Publication date
Aug 22, 2019
Laura Gabriela Lande
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Application
CANINE GENOME EDITING
Publication number
20190223416
Publication date
Jul 25, 2019
Cotyledon, LLC
Matthew Lesko
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
ATOPIC DERMATITIS MODEL NON-HUMAN ANIMAL AND USE THEREOF
Publication number
20190191675
Publication date
Jun 27, 2019
Yoshinori FUKUI
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION
Publication number
20190024086
Publication date
Jan 24, 2019
FLAGSHIP PIONEERING INNOVATIONS V, INC.
Laura Gabriela Lande
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MUTATIONS IN RHODOPSIN GENE IN ZEBRAFISH AND USES THEREOF
Publication number
20180346998
Publication date
Dec 6, 2018
The Florida State University Research Foundation Inc.
James Fadool
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
GENETICALLY MODIFIED RAT MODELS FOR SEVERE COMBINED IMMUNODEFICIENC...
Publication number
20180295819
Publication date
Oct 18, 2018
TRANSPOSAGEN BIOPHARMACEUTICALS, INC.
Eric M. Ostertag
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION
Publication number
20180179525
Publication date
Jun 28, 2018
Flagship Pioneering, Inc.
Laura Gabriela Lande
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING