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C07K14/72

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CCHEMISTRY METALLURGY C07Organic chemistry C07KPEPTIDES C07K14/00Peptides having more than 20 amino acids Gastrins Somatostatins Melanotropins Derivatives thereof

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C07K14/72for hormones

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Patents Grantslast 30 patents

Information Patent Grant
Compositions and methods for oligodendrocyte development
- Patent number 12,358,959
- Issue date Jul 15, 2025
- Children's Medical Center Corporation
- Xianhua Piao
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Cancer antigen targets and uses thereof
- Patent number 12,345,712
- Issue date Jul 1, 2025
- Memorial Sloan Kettering Cancer Center
- Michel Sadelain
- G06 - COMPUTING CALCULATING COUNTING
Information Patent Grant
Methods of detecting alloantibodies using HLA and non-HLA antigens
- Patent number 12,332,243
- Issue date Jun 17, 2025
- ONE LAMBDA, INC.
- Neng Jen Remi Shih
- G01 - MEASURING TESTING
Information Patent Grant
Treatment of spinal and bulbar muscular atrophy
- Patent number 12,331,101
- Issue date Jun 17, 2025
- Oxford University Innovation Limited
- Carlo Rinaldi
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modified channel rhodopsin
- Patent number 12,325,729
- Issue date Jun 10, 2025
- National University Corporation, Iwate University
- Hiroshi Tomita
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Transduced T cells expressing human SSTR2 and application thereof
- Patent number 12,325,736
- Issue date Jun 10, 2025
- Cornell University
- Moonsoo Jin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Targeting of melanocytes for delivering therapeutic or diagnostic a...
- Patent number 12,303,555
- Issue date May 20, 2025
- Nanyang Technological University
- Sierin Lim
- B82 - NANO-TECHNOLOGY
Information Patent Grant
Inhibitors of complement factor H
- Patent number 12,286,471
- Issue date Apr 29, 2025
- Duke University
- Edward F. Patz
- G01 - MEASURING TESTING
Information Patent Grant
Method of treating melanocortin-4 receptor pathway-associated disor...
- Patent number 12,263,202
- Issue date Apr 1, 2025
- RHYTHM PHARMACEUTICALS, INC.
- Leonardus H. T. Van Der Ploeg
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Cancer antigen targets and uses thereof
- Patent number 12,259,390
- Issue date Mar 25, 2025
- Memorial Sloan Kettering Cancer Center
- Michel Sadelain
- G06 - COMPUTING CALCULATING COUNTING
Information Patent Grant
Compositions and methods for treating and/or preventing pathogenic...
- Patent number 12,240,890
- Issue date Mar 4, 2025
- The University of Chicago
- Eugene B. Chang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Peptides and combination of peptides for use in immunotherapy again...
- Patent number 12,226,466
- Issue date Feb 18, 2025
- Immatics Biotechnologies GmbH
- Andrea Mahr
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Peptides and combination of peptides for use in immunotherapy again...
- Patent number 12,226,467
- Issue date Feb 18, 2025
- Immatics Biotechnologies GmbH
- Andrea Mahr
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
APJ antibody, fusion protein thereof with Elabela, and pharmaceutic...
- Patent number 12,221,488
- Issue date Feb 11, 2025
- Cheng Zhang
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Compositions and methods for treating type 1 and type 2 diabetes an...
- Patent number 12,213,999
- Issue date Feb 4, 2025
- Salk Institute for Biological Studies
- Ronald M. Evans
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Peptides and combination of peptides for use in immunotherapy again...
- Patent number 12,193,999
- Issue date Jan 14, 2025
- Immatics Biotechnologies GmbH
- Andrea Mahr
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Peptides and combination of peptides for use in immunotherapy again...
- Patent number 12,193,997
- Issue date Jan 14, 2025
- Immatics Biotechnologies GmbH
- Andrea Mahr
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Peptides and combination of peptides for use in immunotherapy again...
- Patent number 12,193,998
- Issue date Jan 14, 2025
- Immatics Biotechnologies GmbH
- Andrea Mahr
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Peptides and combination of peptides for use in immunotherapy again...
- Patent number 12,186,276
- Issue date Jan 7, 2025
- Immatics Biotechnologies GmbH
- Andrea Mahr
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Peptides and combination of peptides for use in immunotherapy again...
- Patent number 12,186,277
- Issue date Jan 7, 2025
- Immatics Biotechnologies GmbH
- Andrea Mahr
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Peptides and combination of peptides for use in immunotherapy again...
- Patent number 12,171,819
- Issue date Dec 24, 2024
- Immatics Biotechnologies GmbH
- Andrea Mahr
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Melanocortin 1 receptor ligands and methods of use
- Patent number 12,173,087
- Issue date Dec 24, 2024
- H. Lee Moffitt Cancer Center & Research Institute, Inc.
- Robert J. Gillies
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Peptides and combination of peptides for use in immunotherapy again...
- Patent number 12,168,043
- Issue date Dec 17, 2024
- Immatics Biotechnologies GmbH
- Andrea Mahr
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Synthetic odorant receptors
- Patent number 12,163,950
- Issue date Dec 10, 2024
- Duke University
- Hiroaki Matsunami
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inducible chimeric cytokine receptors
- Patent number 12,163,169
- Issue date Dec 10, 2024
- Allogene Therapeutics, Inc.
- Andrew Ross Nager
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
G- protein coupled receptor extraction formulations
- Patent number 12,123,814
- Issue date Oct 22, 2024
- Pierce Biotechnology, Inc.
- Barbara Kaboord
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Estrogen receptor mutations and uses thereof
- Patent number 12,116,638
- Issue date Oct 15, 2024
- Foundation Medicine, Inc.
- Maureen T. Cronin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Cells expressing recombinant growth factor receptors
- Patent number 12,116,564
- Issue date Oct 15, 2024
- INSTIL BIO (UK) LIMITED
- John Stephen Bridgeman
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
G protein-coupled receptor (GPCR) ligand assay
- Patent number 12,098,184
- Issue date Sep 24, 2024
- Regents of The University of Minnesota
- Sivaraj Sivaramakrishnan
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Protein binding domains stabilizing functional conformational state...
- Patent number 12,092,646
- Issue date Sep 17, 2024
- Trustees of Leland Stanford Junior University
- Jan Steyaert
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
LIVE CELL IMAGING PLATFORM FOR CONDENSATES
- Publication number 20250231175
- Publication date Jul 17, 2025
- UMC Utrecht Holding B.V.
- Boudewijn Marius Theodoor BURGERING
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CELLS DERIVED FROM POLYPEDILUM VANDERPLANKI AND ODOR SENSOR EQUIPPE...
- Publication number 20250197799
- Publication date Jun 19, 2025
- University of Maryland, College Park
- Elisabeth Smela
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISOR...
- Publication number 20250195606
- Publication date Jun 19, 2025
- RHYTHM PHARMACEUTICALS, INC.
- Leonardus H.T. Van Der Ploeg
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SYSTEMS AND METHODS FOR GENETIC MODULATION TO TREAT OCULAR DISEASES
- Publication number 20250188452
- Publication date Jun 12, 2025
- Epicrispr Biotechnologies, Inc.
- Alexandra Sylvie COLLIN DE L'HORTET
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITION FOR TREATING OR PREVENTING DISEASES, DISORDERS, OR COND...
- Publication number 20250186617
- Publication date Jun 12, 2025
- Restore Vision Inc.
- Toshihide Kurihara
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ENHANCING ESTROGEN RECEPTOR ALPHA IN OSTEOARTHRITIS
- Publication number 20250188149
- Publication date Jun 12, 2025
- University of Pittsburgh of the Commonwealth System of Higher Education
- Hang Lin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LONG-ACTING GLP-1/GLP-2 DUAL AGONIST COMPOUND
- Publication number 20250154226
- Publication date May 15, 2025
- CHENGDU AODA BIOTECHNOLOGY CO., LTD
- Haining YU
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY...
- Publication number 20250144192
- Publication date May 8, 2025
- Immatics Biotechnologies GmbH
- Andrea MAHR
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NOVEL ESTROGEN RECEPTOR MUTATIONS AND USES THEREOF
- Publication number 20250146077
- Publication date May 8, 2025
- Foundation Medicine, Inc.
- Maureen T. Cronin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE
- Publication number 20250129118
- Publication date Apr 24, 2025
- H. Lee Moffitt Cancer Center & Research Institute, Inc.
- Robert J. GILLIES
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CHIMERIC CD40 POLYPEPTIDES AND METHODS OF USE IN IMMUNOTHERAPY
- Publication number 20250073268
- Publication date Mar 6, 2025
- Providence Health & Services - Oregon
- Eric Tran
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A TRANSCRIPTION FACTOR AN...
- Publication number 20250074959
- Publication date Mar 6, 2025
- SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE
- Michael C. Jensen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HER-1, HER-3 AND IGF-1R COMPOSITIONS AND USES THEREOF
- Publication number 20250059256
- Publication date Feb 20, 2025
- Ohio State Innovation Foundation
- Pravin T.P. KAUMAYA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RECOMBINANT PROTEIN OF GPER
- Publication number 20250042973
- Publication date Feb 6, 2025
- Wuhan University
- Jin XIANG
- G01 - MEASURING TESTING
Information Patent Application
GENETIC CONSTRUCT FOR TRACKING AND/OR ABLATING QUIESCENT CELLS
- Publication number 20250043305
- Publication date Feb 6, 2025
- UNIVERSITÀ DEGLI STUDI DI TRENTO
- Luca TIBERI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
20-HETE RECEPTOR (GPR75) ANTAGONISTS AND METHODS OF USE
- Publication number 20250032453
- Publication date Jan 30, 2025
- Board of Regents, The University of Texas System
- John R. Falck
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR INDUCING ESR1, PI3K, HER2, AND HER3 IM...
- Publication number 20250027110
- Publication date Jan 23, 2025
- Replicate Bioscience, Inc.
- Nathaniel Stephen WANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Screening Assays, Modulators and Modulation of Activation of Recept...
- Publication number 20250019415
- Publication date Jan 16, 2025
- MONASH UNIVERSITY
- Kevin Donald George PFLEGER
- C07 - ORGANIC CHEMISTRY
Information Patent Application
HUMANIZED ANTI-PACAP ANTIBODIES AND USES THEREOF
- Publication number 20250009876
- Publication date Jan 9, 2025
- H. LUNDBECK A/S
- Maria-Cristina LOOMIS
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ULTRA LIGHT-SENSITIVE NEUROPSIN-BASED OPTOGENETIC TOOL FOR ACTIVATI...
- Publication number 20250011391
- Publication date Jan 9, 2025
- GENANS BIOTECHNOLOGY CO., LTD
- Tao Yu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PHARMACEUTICAL FORMULATION FOR TREATMENT OF CEREBRAL STROKE
- Publication number 20250002559
- Publication date Jan 2, 2025
- Pharmazz, Inc.
- Anil Gulati
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
RECOMBINANT THYROID-STIMULATING HORMONE RECEPTOR PROTEIN, PREPARATI...
- Publication number 20240426837
- Publication date Dec 26, 2024
- XIAMEN INNOBIOMAX BIOTECHNOLOGY CO., LTD.
- Haihong WANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GENERATION OF HUMAN PLURIPOTENT STEM CELL DERIVED FUNCTIONAL BETA C...
- Publication number 20240417693
- Publication date Dec 19, 2024
- JANSSEN BIOTECH, INC.
- Sebastian Rieck
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADA...
- Publication number 20240398959
- Publication date Dec 5, 2024
- C4 Therapeutics, Inc.
- Andrew J. Phillips
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOSITIONS AND METHODS FOR MODULATING MOLECULES
- Publication number 20240400642
- Publication date Dec 5, 2024
- Etern Therapeutics Inc.
- Guangya ZHU
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Novel Animal Model for Autoimmune Disease
- Publication number 20240349706
- Publication date Oct 24, 2024
- Industry-Academic Cooperation Foundation, Yonsei University
- Eun Jig Lee
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
INHIBITORS OF COMPLEMENT FACTOR H
- Publication number 20240352101
- Publication date Oct 24, 2024
- DUKE UNIVERSITY
- Edward F. Patz
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PHARMACOLOGICAL AND/OR GENETIC ACTIVATOR FOR USE IN PRESERVING AND...
- Publication number 20240343779
- Publication date Oct 17, 2024
- Institut National de la Sante et de la Recherche Medicale (INSERM)
- Valentina TAGLIETTI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NUCLEIC ACIDS ENCODING ANCHOR MODIFIED ANTIBODIES AND USES THEREOF
- Publication number 20240317849
- Publication date Sep 26, 2024
- Regeneron Pharmaceuticals, Inc.
- Jason Mastaitis
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE
- Publication number 20240299366
- Publication date Sep 12, 2024
- Arvinas Operations, Inc.
- Andrew P. CREW
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

for hormones

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Compositions and methods for oligodendrocyte development

Cancer antigen targets and uses thereof

Methods of detecting alloantibodies using HLA and non-HLA antigens

Treatment of spinal and bulbar muscular atrophy

Modified channel rhodopsin

Transduced T cells expressing human SSTR2 and application thereof

Targeting of melanocytes for delivering therapeutic or diagnostic a...

Inhibitors of complement factor H

Method of treating melanocortin-4 receptor pathway-associated disor...

Cancer antigen targets and uses thereof

Compositions and methods for treating and/or preventing pathogenic...

Peptides and combination of peptides for use in immunotherapy again...

Peptides and combination of peptides for use in immunotherapy again...

APJ antibody, fusion protein thereof with Elabela, and pharmaceutic...

Compositions and methods for treating type 1 and type 2 diabetes an...

Peptides and combination of peptides for use in immunotherapy again...

Peptides and combination of peptides for use in immunotherapy again...

Peptides and combination of peptides for use in immunotherapy again...

Peptides and combination of peptides for use in immunotherapy again...

Peptides and combination of peptides for use in immunotherapy again...

Peptides and combination of peptides for use in immunotherapy again...

Melanocortin 1 receptor ligands and methods of use

Peptides and combination of peptides for use in immunotherapy again...

Synthetic odorant receptors

Inducible chimeric cytokine receptors

G- protein coupled receptor extraction formulations

Estrogen receptor mutations and uses thereof

Cells expressing recombinant growth factor receptors

G protein-coupled receptor (GPCR) ligand assay

Protein binding domains stabilizing functional conformational state...

Patents Applicationslast 30 patents

LIVE CELL IMAGING PLATFORM FOR CONDENSATES

CELLS DERIVED FROM POLYPEDILUM VANDERPLANKI AND ODOR SENSOR EQUIPPE...

METHOD OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISOR...

SYSTEMS AND METHODS FOR GENETIC MODULATION TO TREAT OCULAR DISEASES

COMPOSITION FOR TREATING OR PREVENTING DISEASES, DISORDERS, OR COND...

ENHANCING ESTROGEN RECEPTOR ALPHA IN OSTEOARTHRITIS

LONG-ACTING GLP-1/GLP-2 DUAL AGONIST COMPOUND

NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY...

NOVEL ESTROGEN RECEPTOR MUTATIONS AND USES THEREOF

MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE

CHIMERIC CD40 POLYPEPTIDES AND METHODS OF USE IN IMMUNOTHERAPY

ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A TRANSCRIPTION FACTOR AN...

HER-1, HER-3 AND IGF-1R COMPOSITIONS AND USES THEREOF

RECOMBINANT PROTEIN OF GPER

GENETIC CONSTRUCT FOR TRACKING AND/OR ABLATING QUIESCENT CELLS

20-HETE RECEPTOR (GPR75) ANTAGONISTS AND METHODS OF USE

COMPOSITIONS AND METHODS FOR INDUCING ESR1, PI3K, HER2, AND HER3 IM...

Screening Assays, Modulators and Modulation of Activation of Recept...

HUMANIZED ANTI-PACAP ANTIBODIES AND USES THEREOF

ULTRA LIGHT-SENSITIVE NEUROPSIN-BASED OPTOGENETIC TOOL FOR ACTIVATI...

PHARMACEUTICAL FORMULATION FOR TREATMENT OF CEREBRAL STROKE

RECOMBINANT THYROID-STIMULATING HORMONE RECEPTOR PROTEIN, PREPARATI...

GENERATION OF HUMAN PLURIPOTENT STEM CELL DERIVED FUNCTIONAL BETA C...

C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADA...

COMPOSITIONS AND METHODS FOR MODULATING MOLECULES

Novel Animal Model for Autoimmune Disease

INHIBITORS OF COMPLEMENT FACTOR H

PHARMACOLOGICAL AND/OR GENETIC ACTIVATOR FOR USE IN PRESERVING AND...

NUCLEIC ACIDS ENCODING ANCHOR MODIFIED ANTIBODIES AND USES THEREOF

IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE