Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:

CCHEMISTRY METALLURGY C07Organic chemistry C07DHETEROCYCLIC COMPOUNDS

C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:

C07D501/02Preparation C07D501/04from compounds already containing the ring or condensed ring systems C07D501/06Acylation of 7-aminocephalosporanic acid C07D501/08by forming the ring or condensed ring systems C07D501/10from compounds containing the penicillin ring system C07D501/12Separation Purification C07D501/14Compounds having a nitrogen atom directly attached in position 7 C07D501/16with a double bond between positions 2 and 3 C07D501/187-Aminocephalosporanic or substituted 7-aminocephalosporanic acids C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids C07D501/22with radicals containing only hydrogen and carbon atoms, attached in position 3 C07D501/24with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3 C07D501/26Methylene radicals, substituted by oxygen atoms Lactones thereof with the 2-carboxyl group C07D501/28with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms C07D501/30with the 7-amino-radical acylated by an araliphatic carboxylic acid C07D501/32with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms C07D501/34with the 7-amino radical acylated by carboxylic acids containing hetero rings C07D501/36Methylene radicals, substituted by sulfur atoms C07D501/38Methylene radicals, substituted by nitrogen atoms Lactams thereof with the 2-carboxyl group Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom Quaternary compounds thereof C07D501/40with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms C07D501/42with the 7-amino radical acylated by an araliphatic carboxylic acid C07D501/44with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms C07D501/46with the 7-amino radical acylated by carboxylic acids containing hetero rings C07D501/48Methylene radicals, substituted by hetero rings C07D501/50with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms C07D501/52with the 7-amino radical acylated by an araliphatic carboxylic acid C07D501/54with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms C07D501/56with the 7-amino radical acylated by carboxylic acids containing hetero rings C07D501/57with a further substituent in position 7 C07D501/58with a nitrogen atom, which is a member of a hetero ring, attached in position 7 C07D501/59with hetero atoms directly attached in position 3 C07D501/60with a double bond between positions 3 and 4 C07D501/62Compounds further condensed with a carbocyclic ring or ring system