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Combinatorial chemistry
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COMBINATORIAL CHEMISTRY LIBRARIES
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Methods specially adapted for identifying library members
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C40B20/02
Identifying library members by their fixed physical location on a support or substrate
C40B20/04
Identifying library members by means of a tag, label, or other readable or detectable entity associated with the library members
C40B20/06
using iterative deconvolution techniques
C40B20/08
Direct analysis of the library members per se by physical methods
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Patents Grants
last 30 patents
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Patent Grant
High resolution spatial genomic analysis of tissues and cell aggreg...
Patent number
12,168,226
Issue date
Dec 17, 2024
BioSkryb Genomics, Inc.
Jason A. A. West
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods of engineering transferrin receptor binding polypeptides
Patent number
12,162,948
Issue date
Dec 10, 2024
Denali Therapeutics Inc.
Xiaocheng Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods, systems, computer readable media, and kits for sample iden...
Patent number
12,146,189
Issue date
Nov 19, 2024
Life Technologies Corporation
Earl Hubbell
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Determination of JAK-STAT3 pathway activity using unique combinatio...
Patent number
12,125,561
Issue date
Oct 22, 2024
InnoSIGN B.V.
Meng Dou
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Directed evolution of enzymes by plasmid tagging in droplets
Patent number
12,116,570
Issue date
Oct 15, 2024
Roche Sequencing Solutions, Inc.
Mark Stamatios Kokoris
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Method for generating higher order genome editing libraries
Patent number
12,091,656
Issue date
Sep 17, 2024
Johann Wolfgang Goethe-Universität Frankfur
Manuel Kaulich
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA structure library
Patent number
12,091,775
Issue date
Sep 17, 2024
Kyoto University
Hirohide Saito
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Microfluidic analysis of ligand induced cell expression
Patent number
12,083,512
Issue date
Sep 10, 2024
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Hongxing Hu
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Grant
Library preparation methods and compositions and uses therefor
Patent number
12,065,643
Issue date
Aug 20, 2024
Life Technologies Corporation
Mark Andersen
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Engineering AAV
Patent number
11,981,967
Issue date
May 14, 2024
Sangamo Therapeutics, Inc.
Kyle McGovern
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and kits for detecting contamination and sample misidentifi...
Patent number
11,970,786
Issue date
Apr 30, 2024
Bioo Scientific Corporation
Shannon Piehl
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Digital protein quantification
Patent number
11,965,891
Issue date
Apr 23, 2024
Bio-Rad Laboratories, Inc.
Jeremy Agresti
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and systems for microfluidic screening
Patent number
11,919,000
Issue date
Mar 5, 2024
1859, Inc.
Devon Cayer
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Grant
System and method for isolation and qualification of nucleic acids
Patent number
11,913,062
Issue date
Feb 27, 2024
Roche Sequencing Solutions, Inc.
Victoria Constandse
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Methods of engineering transferrin receptor binding polypeptides
Patent number
11,912,778
Issue date
Feb 27, 2024
Denali Therapeutics Inc.
Xiaocheng Chen
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Functionalized gel beads
Patent number
11,884,962
Issue date
Jan 30, 2024
10X GENOMICS, INC.
Zachary Bent
G06 - COMPUTING CALCULATING COUNTING
Information
Patent Grant
Enrichment of short nucleic acid fragments in sequencing library pr...
Patent number
11,851,650
Issue date
Dec 26, 2023
GRAIL, LLC
Byoungsok Jung
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Methods and compositions for identifying epitopes
Patent number
11,834,653
Issue date
Dec 5, 2023
The Brigham & Women's Hospital, Inc.
Stephen Elledge
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Compositions, methods and systems for processing or analyzing multi...
Patent number
11,814,750
Issue date
Nov 14, 2023
Personalis, Inc.
John West
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Mammalian cell line for protein production and library generation
Patent number
11,802,281
Issue date
Oct 31, 2023
ETH ZURICH
Sai Reddy
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Platform for discovery and analysis of therapeutic agents
Patent number
11,795,581
Issue date
Oct 24, 2023
Illumina, Inc.
Molly He
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Grant
Methods for next generation genome walking and related compositions...
Patent number
11,795,501
Issue date
Oct 24, 2023
Sigma-Aldrich Co. LLC
Brian Ward
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
High-throughput single-cell polyomics
Patent number
11,753,743
Issue date
Sep 12, 2023
Yale University
Rong Fan
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
DNA barcoding of designer mononucleosome and chromatin array librar...
Patent number
11,753,744
Issue date
Sep 12, 2023
The Trustees of Princeton University
Tom W. Muir
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Lanthanide-chelator combinatorial barcoding
Patent number
11,738,321
Issue date
Aug 29, 2023
The Regents of the University of California
Todd Duncombe
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Positional delivery and encoding by oligonucleotides of biological...
Patent number
11,739,327
Issue date
Aug 29, 2023
International Business Machines Corporation
Pablo Meyer Rojas
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Methods and systems for processing polynucleotides
Patent number
11,713,457
Issue date
Aug 1, 2023
10X GENOMICS, INC.
Benjamin Hindson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for detecting and identifying genomic nucleic acids
Patent number
11,697,839
Issue date
Jul 11, 2023
President and Fellows of Harvard College
Evan R. Daugharthy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Construction of next generation sequencing (NGS) libraries using co...
Patent number
11,692,219
Issue date
Jul 4, 2023
Integrated DNA Technologies, Inc.
Zachary Zwirko
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Concealing information present within nucleic acids
Patent number
11,667,951
Issue date
Jun 6, 2023
GENEINFOSEC, INC.
Sterling Sawaya
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
LIBRARY PREPARATION METHODS AND COMPOSITIONS AND USES THEREFOR
Publication number
20250011760
Publication date
Jan 9, 2025
Life Technologies Corporation
Mark ANDERSEN
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
DIRECTED EVOLUTION OF ENZYMES BY PLASMID TAGGING IN DROPLETS
Publication number
20250002899
Publication date
Jan 2, 2025
Roche Sequencing Solutions, Inc.
Mark Stamatios Kokoris
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENGINEERING AAV
Publication number
20240392392
Publication date
Nov 28, 2024
Sangamo Therapeutics, Inc.
Kyle McGovern
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR IDENTIFYING EPITOPES
Publication number
20240318168
Publication date
Sep 26, 2024
The Brigham & Women's Hospital, Inc.
Stephen Elledge
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
METHODS OF ENGINEERING TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES
Publication number
20240271326
Publication date
Aug 15, 2024
Denali Therapeutics Inc.
Xiaocheng Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS OF ENGINEERING TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES
Publication number
20240271327
Publication date
Aug 15, 2024
Denali Therapeutics Inc.
Xiaocheng Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
HIGH-THROUGHPUT SINGLE-CELL POLYOMICS
Publication number
20240263353
Publication date
Aug 8, 2024
Yale University
Rong Fan
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Application
PROCESSES AND SYSTEMS FOR PREPARATION OF NUCLEIC ACID SEQUENCING LI...
Publication number
20240191271
Publication date
Jun 13, 2024
10X Genomics, Inc.
Paul Hardenbol
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS OF ENGINEERING TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES
Publication number
20240141058
Publication date
May 2, 2024
Denali Therapeutics Inc.
Xiaocheng Chen
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
COMPOSITIONS, METHODS AND SYSTEMS FOR PROCESSING OR ANALYZING MULTI...
Publication number
20240110311
Publication date
Apr 4, 2024
Personalis, Inc.
John West
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENRICHMENT OF SHORT NUCLEIC ACID FRAGMENTS IN SEQUENCING LIBRARY PR...
Publication number
20240084289
Publication date
Mar 14, 2024
GRAIL, LLC
Byoungsok Jung
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
METHODS FOR NEXT GENERATION GENOME WALKING AND RELATED COMPOSITIONS...
Publication number
20240068020
Publication date
Feb 29, 2024
Sigma-Aldrich Co. LLC
Brian Ward
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PLATFORM FOR DISCOVERY AND ANALYSIS OF THERAPEUTIC AGENTS
Publication number
20240003057
Publication date
Jan 4, 2024
Illumina, Inc.
Molly He
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND SYSTEMS FOR PROCESSING POLYNUCLEOTIDES
Publication number
20240002837
Publication date
Jan 4, 2024
10X Genomics, Inc.
Benjamin Hindson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MAMMALIAN CELL LINE FOR PROTEIN PRODUCTION AND LIBRARY GENERATION
Publication number
20230374491
Publication date
Nov 23, 2023
ETH ZURICH
Sai REDDY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND SYSTEMS FOR PROCESSING POLYNUCLEOTIDES
Publication number
20230348897
Publication date
Nov 2, 2023
10X Genomics, Inc.
Benjamin Hindson
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
THERAPEUTIC DRUG FOR LIPID-PEROXIDATION-INDUCED DISEASES AND SCREEN...
Publication number
20230324358
Publication date
Oct 12, 2023
Fuso Pharmaceutical Industries, Ltd.
Ken-ichi YAMADA
C01 - INORGANIC CHEMISTRY
Information
Patent Application
THERAPEUTIC DRUG FOR LIPID-PEROXIDATION-INDUCED DISEASES AND SCREEN...
Publication number
20230324359
Publication date
Oct 12, 2023
FUSO PHARMACEUTICAL INDUSTRIES, LTD.
Ken-ichi YAMADA
C01 - INORGANIC CHEMISTRY
Information
Patent Application
Positional Delivery and Encoding by Oligonucleotides of Biological...
Publication number
20230313192
Publication date
Oct 5, 2023
International Business Machines Corporation
Pablo Meyer Rojas
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TCR ENGINEERING WITH DEEP REINFORCEMENT LEARNING FOR INCREASING EFF...
Publication number
20230304189
Publication date
Sep 28, 2023
NEC Laboratories America, Inc.
Renqiang Min
G06 - COMPUTING CALCULATING COUNTING
Information
Patent Application
BARCODABLE EXCHANGEABLE PEPTIDE-MHC MULTIMER LIBRARIES
Publication number
20230287394
Publication date
Sep 14, 2023
REPERTOIRE IMMUNE MEDICINES, INC.
Ohad Yosefson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NUCLEIC ACID-GUIDED EDITING OF EXOGENOUS POLYNUCLEOTIDES IN HETEROL...
Publication number
20230235482
Publication date
Jul 27, 2023
Inscripta, Inc.
Richard Fox
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR PROTEIN IDENTIFICATION BASED ON ENCODING REACTIONS
Publication number
20230193248
Publication date
Jun 22, 2023
Encodia, Inc.
Sean SUASTEGUI
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
BACTERIAL DELIVERY VEHICLES COMPRISING TRACER NUCLEIC ACID SEQUENCES
Publication number
20230112827
Publication date
Apr 13, 2023
ELIGO BIOSCIENCE
Igor STZEPOURGINSKI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND SYSTEMS FOR PROCESSING POLYNUCLEOTIDES
Publication number
20230087127
Publication date
Mar 23, 2023
10xGenomics, Inc.
Benjamin Hindson
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
METHODS FOR INFORMATION TRANSFER AND RELATED KITS
Publication number
20230056532
Publication date
Feb 23, 2023
Encodia, Inc.
Kevin L. GUNDERSON
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
Methods for Determining Lymphocyte Receptor Chain Pairs
Publication number
20230041481
Publication date
Feb 9, 2023
The University of British Columbia
Carl Lars, Genghis HANSEN
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
NUCLEIC ACID COMPLEXES FOR SCREENING BARCODED COMPOUNDS
Publication number
20230045556
Publication date
Feb 9, 2023
Children's Medical Center Corporation
Wesley Philip Wong
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
ENCAPSULATION OF EUKARYOTIC CELLS FOR CELLULAR SCREENING OF EXPRESS...
Publication number
20220380936
Publication date
Dec 1, 2022
The Florey Institute of Neuroscience and Mental Health
Daniel James Scott
G01 - MEASURING TESTING
Information
Patent Application
RAPID CHARACTERIZATION OF CAS ENDONUCLEASE SYSTEMS, PAM SEQUENCES A...
Publication number
20220356485
Publication date
Nov 10, 2022
PIONEER HI-BRED INTERNATIONAL, INC.
ANDREW MARK CIGAN
C40 - COMBINATORIAL CHEMISTRY