Pyrazines or piperazines forming part of bridged ring systems

Industry

CPC
A61K31/4995

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Parent Industries

AHUMAN NECESSITIES A61Medical science A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES A61K31/00Medicinal preparations containing organic active ingredients

Current Industry

A61K31/4995Pyrazines or piperazines forming part of bridged ring systems

Industries

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Patents Grantslast 30 patents

Information Patent Grant
Bile acid recycling inhibitors for treatment of pediatric cholestat...
- Patent number 12,350,267
- Issue date Jul 8, 2025
- Shire Human Genetic Therapies, Inc.
- Bronislava Gedulin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bromodomain inhibitors to target therapy-resistant cancer
- Patent number 12,329,755
- Issue date Jun 17, 2025
- University of Tennessee Research Foundation
- Duane Miller
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modulators of cystic fibrosis transmembrane conductance regulator
- Patent number 12,324,802
- Issue date Jun 10, 2025
- Vertex Pharmaceuticals Incorporated
- Jeremy J. Clemens
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Method of treating SCLC and managing hepatotoxicity
- Patent number 12,324,806
- Issue date Jun 10, 2025
- Pharma Mar, S.A.
- Carmen Kahatt
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treatment
- Patent number 12,318,384
- Issue date Jun 3, 2025
- BOW RIVER LLC
- Sundar Srinivasan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Trabectedin composition
- Patent number 12,303,506
- Issue date May 20, 2025
- EXTROVIS AG
- Krishna Mohan Chilakala
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Pharmaceutical compositions comprising maralixibat and uses thereof
- Patent number 12,296,050
- Issue date May 13, 2025
- MIRUM PHARMACEUTICALS, INC.
- Parag Ved
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Halogenation of complex organic compounds
- Patent number 12,252,714
- Issue date Mar 18, 2025
- Regents of the University of Michigan
- David H. Sherman
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Therapeutic agent for inflammatory diseases, autoimmune diseases, f...
- Patent number 12,239,643
- Issue date Mar 4, 2025
- Meiji Seika Pharma Co., Ltd.
- Natsuki Ishida
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bile acid recycling inhibitors for treatment of hypercholemia and c...
- Patent number 12,145,959
- Issue date Nov 19, 2024
- Shire Human Genetic Therapies, Inc.
- Bronislava Gedulin
- Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMA...
Information Patent Grant
Compositions comprising macrocycle derivatives incorporating bridge...
- Patent number 12,139,481
- Issue date Nov 12, 2024
- Southwestern Oklahoma State University
- Timothy J. Hubin
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Bicyclic heterocycles as FGFR inhibitors
- Patent number 12,083,124
- Issue date Sep 10, 2024
- Incyte Corporation
- Oleg Vechorkin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Substituted 1H-pyrazolo[4,3-c]pyridines and derivatives as EGFR inh...
- Patent number 12,064,421
- Issue date Aug 20, 2024
- Boehringer Ingelheim International GmbH
- Harald Engelhardt
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treatment
- Patent number 12,016,859
- Issue date Jun 25, 2024
- BOW RIVER LLC
- Sundar Srinivasan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors
- Patent number 11,998,545
- Issue date Jun 4, 2024
- Array Biopharma Inc.
- Steven W. Andrews
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treatment
- Patent number 11,974,998
- Issue date May 7, 2024
- BOW RIVER LLC
- Sundar Srinivasan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods for treating cholestasis
- Patent number 11,918,578
- Issue date Mar 5, 2024
- MIRUM PHARMACEUTICALS, INC.
- Thomas Jaecklin
- G01 - MEASURING TESTING
Information Patent Grant
Compositions and use of varenicline for treating dry eye
- Patent number 11,911,380
- Issue date Feb 27, 2024
- Oyster Point Pharma, Inc.
- Douglas Michael Ackermann
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and use of varenicline for treating dry eye
- Patent number 11,903,942
- Issue date Feb 20, 2024
- Oyster Point Pharma, Inc.
- Douglas Michael Ackermann
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and use of varenicline for treating dry eye
- Patent number 11,903,941
- Issue date Feb 20, 2024
- Oyster Point Pharma, Inc.
- Douglas Michael Ackermann
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and use of varenicline for treating dry eye
- Patent number 11,903,943
- Issue date Feb 20, 2024
- Oyster Point Pharma, Inc.
- Douglas Michael Ackermann
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treatment
- Patent number 11,857,548
- Issue date Jan 2, 2024
- BOW RIVER LLC
- Sundar Srinivasan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treating cancer
- Patent number 11,801,245
- Issue date Oct 31, 2023
- BOW RIVER LLC
- Sundar Srinivasan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
KDM1A inhibitors for the treatment of disease
- Patent number 11,773,068
- Issue date Oct 3, 2023
- Imago Biosciences, Inc.
- Hugh Y. Rienhoff
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Muscarinic acetylcholine M1 receptor antagonists
- Patent number 11,752,149
- Issue date Sep 12, 2023
- Pipeline Therapeutics, Inc.
- Yifeng Xiong
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treatment
- Patent number 11,730,724
- Issue date Aug 22, 2023
- BOW RIVER LLC
- Sundar Srinivasan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Halogenation of complex organic compounds
- Patent number 11,692,176
- Issue date Jul 4, 2023
- Regents of the University of Michigan
- David H. Sherman
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Aromatic heterocyclic compound, and pharmaceutical composition and...
- Patent number 11,679,108
- Issue date Jun 20, 2023
- GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD.
- Jiancun Zhang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Combinations of estrogen receptor degraders and cyclin-dependent ki...
- Patent number 11,642,342
- Issue date May 9, 2023
- Accutar Biotechnology
- Jie Fan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Asymmetric bisaminoquinolines and bisaminoquinolines with varied li...
- Patent number 11,639,335
- Issue date May 2, 2023
- The Trustees of the University of Pennsylvania
- Ravi K. Amaravadi
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
METHODS OF TREATING OCULAR CONDITIONS
- Publication number 20250235449
- Publication date Jul 24, 2025
- Oyster Point Pharma, Inc.
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOUND HAVING SHP2 PROTEIN DEGRADING ACTIVITY, AND MEDICAL USES T...
- Publication number 20250230154
- Publication date Jul 17, 2025
- UBIX THERAPEUTICS, INC.
- Song Hee LEE
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PYRIDINYLOXYPYRIDINES AND RELATED COMPOUNDS AND THEIR USE IN TREATI...
- Publication number 20250228835
- Publication date Jul 17, 2025
- Rectify Pharmaceuticals, Inc.
- Nathan Oliver Fuller
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER
- Publication number 20250230165
- Publication date Jul 17, 2025
- Artios Pharma Limited
- Owen DAVIS
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTIDIABETIC COMPOUNDS AND COMPOSITIONS
- Publication number 20250223281
- Publication date Jul 10, 2025
- REZUBIO PHARMACEUTICALS CO., LTD
- Hongping GUAN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DIAZABICYCLOOCTANE DERIVATIVES USEFUL AS MATRIX METALLOPROTEINASE I...
- Publication number 20250215010
- Publication date Jul 3, 2025
- VASA THERAPEUTICS SPÓLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA
- Piotr Jakub Lipinski
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHODS OF TREATMENT
- Publication number 20250213557
- Publication date Jul 3, 2025
- Bow River LLC
- Sundar SRINIVASAN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DI...
- Publication number 20250213558
- Publication date Jul 3, 2025
- PRAXIS PRECISION MEDICINES, INC.
- Ricardo Lira
- C07 - ORGANIC CHEMISTRY
Information Patent Application
SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS
- Publication number 20250206722
- Publication date Jun 26, 2025
- The Scripps Research Institute
- Michael J. Bollong
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
HETEROCYCLIC COMPOUND FOR INDUCING DEGRADATION OF G12D MUTANT KRAS...
- Publication number 20250206751
- Publication date Jun 26, 2025
- Astellas Pharma Inc.
- Tomohiro YOSHINARI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AN...
- Publication number 20250206759
- Publication date Jun 26, 2025
- CHENGDU HYPERWAY PHARMACEUTICALS CO., LTD.
- Junfeng REN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
USE OF SOS1 INHIBITORS TO TREAT MALIGNANCIES WITH SHP2 MUTATIONS
- Publication number 20250195521
- Publication date Jun 19, 2025
- Revolution Medicines, Inc.
- Ethan AHLER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PROPIONIC ACID DERIVATIVE AND MEDICAL USE THEREOF
- Publication number 20250195485
- Publication date Jun 19, 2025
- Xizang Haisco Pharmaceutical Co., Ltd.
- Chen ZHANG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOUNDS, COMPOSITIONS, AND METHODS
- Publication number 20250171462
- Publication date May 29, 2025
- Nico Therapeutics, Inc.
- Lydia A. Auch
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING RENAL DIS...
- Publication number 20250170116
- Publication date May 29, 2025
- OSAKA UNIVERSITY
- Ryu NAGATA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CBL-B INHIBITOR, COMPOSITIONS COMPRISING A CBL-B INHIBITOR IN A MET...
- Publication number 20250161278
- Publication date May 22, 2025
- HOTSPOT THERAPEUTICS, INC.
- Fang WANG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PHARMACEUTICAL COMPOSITIONS COMPRISING MARALIXIBAT AND USES THEREOF
- Publication number 20250114310
- Publication date Apr 10, 2025
- Mirum Pharmaceuticals, Inc.
- Parag VED
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMBINATION THERAPY FOR TREATING ABNORMAL CELL GROWTH
- Publication number 20250099467
- Publication date Mar 27, 2025
- VERASTEM, INC.
- Sanjib CHOWDHURY
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREP...
- Publication number 20250084078
- Publication date Mar 13, 2025
- GENFLEFT THERAPEUTICS (SHANGHAI) INC.
- Jichen ZHAO
- C07 - ORGANIC CHEMISTRY
Information Patent Application
INHIBITORS OF SARS-COV-2
- Publication number 20250084091
- Publication date Mar 13, 2025
- THE TEXAS A&M UNIVERSITY SYSTEM
- James C. Sacchettini
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING HEART FAI...
- Publication number 20250073229
- Publication date Mar 6, 2025
- OSAKA UNIVERSITY
- Ryu NAGATA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
HETEROCYCLIC AMIDES AND METHODS OF USING THE SAME
- Publication number 20250066389
- Publication date Feb 27, 2025
- Rgenta Therapeutics, Inc.
- Travis T. Wager
- C07 - ORGANIC CHEMISTRY
Information Patent Application
INHIBITORS OF TRPC6 FOR TREATING FOCAL SEGMENTAL GLOMERULOSCLEROSIS
- Publication number 20250057829
- Publication date Feb 20, 2025
- Boehringer Ingelheim International GmbH
- Roberto Matias NORDABY
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Heterocyclic Compounds and Methods of Use
- Publication number 20250059205
- Publication date Feb 20, 2025
- Amgen Inc.
- Brian Alan Lanman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
6,6-FUSED HETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS
- Publication number 20250059207
- Publication date Feb 20, 2025
- 858 Therapeutics, Inc.
- Zacharia S. CHERUVALLATH
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BICYCLIC HETEROCYCLES AS FGFR INHIBITORS
- Publication number 20250057852
- Publication date Feb 20, 2025
- INCYTE CORPORATION
- Oleg Vechorkin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TRICYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATIO...
- Publication number 20250051321
- Publication date Feb 13, 2025
- Shanghai Jemincare Pharmaceutical Co., Ltd.
- Gang DENG
- C07 - ORGANIC CHEMISTRY
Information Patent Application
5,6,7,8-TETRAHYDRO-2,6-NAPHTHYRIDINE DERIVATIVES AS CANCER THERAPEU...
- Publication number 20250051361
- Publication date Feb 13, 2025
- VRise Therapeutics, Inc.
- Prashant Kashinath BHAVAR
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Substituted Pyrazolopyridines
- Publication number 20250051363
- Publication date Feb 13, 2025
- Neuro3 Therapeutics, Inc.
- Mark Seefeld
- C07 - ORGANIC CHEMISTRY
Information Patent Application
SOS1 Inhibitor With Pyrido-Fused Six-Membered Ring Structure
- Publication number 20250042857
- Publication date Feb 6, 2025
- HAIHE BIOPHARMA CO., LTD.
- Dongsheng LI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Pyrazines or piperazines forming part of bridged ring systems

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Bile acid recycling inhibitors for treatment of pediatric cholestat...

Bromodomain inhibitors to target therapy-resistant cancer

Modulators of cystic fibrosis transmembrane conductance regulator

Method of treating SCLC and managing hepatotoxicity

Methods of treatment

Trabectedin composition

Pharmaceutical compositions comprising maralixibat and uses thereof

Halogenation of complex organic compounds

Therapeutic agent for inflammatory diseases, autoimmune diseases, f...

Bile acid recycling inhibitors for treatment of hypercholemia and c...

Compositions comprising macrocycle derivatives incorporating bridge...

Bicyclic heterocycles as FGFR inhibitors

Substituted 1H-pyrazolo[4,3-c]pyridines and derivatives as EGFR inh...

Methods of treatment

Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors

Methods of treatment

Methods for treating cholestasis

Compositions and use of varenicline for treating dry eye

Compositions and use of varenicline for treating dry eye

Compositions and use of varenicline for treating dry eye

Compositions and use of varenicline for treating dry eye

Methods of treatment

Methods of treating cancer

KDM1A inhibitors for the treatment of disease

Muscarinic acetylcholine M1 receptor antagonists

Methods of treatment

Halogenation of complex organic compounds

Aromatic heterocyclic compound, and pharmaceutical composition and...

Combinations of estrogen receptor degraders and cyclin-dependent ki...

Asymmetric bisaminoquinolines and bisaminoquinolines with varied li...

Patents Applicationslast 30 patents

METHODS OF TREATING OCULAR CONDITIONS

COMPOUND HAVING SHP2 PROTEIN DEGRADING ACTIVITY, AND MEDICAL USES T...

PYRIDINYLOXYPYRIDINES AND RELATED COMPOUNDS AND THEIR USE IN TREATI...

HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER

ANTIDIABETIC COMPOUNDS AND COMPOSITIONS

DIAZABICYCLOOCTANE DERIVATIVES USEFUL AS MATRIX METALLOPROTEINASE I...

METHODS OF TREATMENT

T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DI...

SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS

HETEROCYCLIC COMPOUND FOR INDUCING DEGRADATION OF G12D MUTANT KRAS...

FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AN...

USE OF SOS1 INHIBITORS TO TREAT MALIGNANCIES WITH SHP2 MUTATIONS

PROPIONIC ACID DERIVATIVE AND MEDICAL USE THEREOF

COMPOUNDS, COMPOSITIONS, AND METHODS

PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING RENAL DIS...

CBL-B INHIBITOR, COMPOSITIONS COMPRISING A CBL-B INHIBITOR IN A MET...

PHARMACEUTICAL COMPOSITIONS COMPRISING MARALIXIBAT AND USES THEREOF

COMBINATION THERAPY FOR TREATING ABNORMAL CELL GROWTH

FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREP...

INHIBITORS OF SARS-COV-2

PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING HEART FAI...

HETEROCYCLIC AMIDES AND METHODS OF USING THE SAME

INHIBITORS OF TRPC6 FOR TREATING FOCAL SEGMENTAL GLOMERULOSCLEROSIS

Heterocyclic Compounds and Methods of Use

6,6-FUSED HETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS

BICYCLIC HETEROCYCLES AS FGFR INHIBITORS

TRICYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATIO...

5,6,7,8-TETRAHYDRO-2,6-NAPHTHYRIDINE DERIVATIVES AS CANCER THERAPEU...

Substituted Pyrazolopyridines

SOS1 Inhibitor With Pyrido-Fused Six-Membered Ring Structure