Spiro-condensed pyrazines or piperazines

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CPC
A61K31/499

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Parent Industries

AHUMAN NECESSITIES A61Medical science A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES A61K31/00Medicinal preparations containing organic active ingredients

Current Industry

A61K31/499Spiro-condensed pyrazines or piperazines

Industries

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Patents Grantslast 30 patents

Information Patent Grant
Methods of treatment
- Patent number 12,318,384
- Issue date Jun 3, 2025
- BOW RIVER LLC
- Sundar Srinivasan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Trabectedin composition
- Patent number 12,303,506
- Issue date May 20, 2025
- EXTROVIS AG
- Krishna Mohan Chilakala
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Pharmaceutical compositions comprising maralixibat and uses thereof
- Patent number 12,296,050
- Issue date May 13, 2025
- MIRUM PHARMACEUTICALS, INC.
- Parag Ved
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Pyrazole MAGL inhibitors
- Patent number 12,258,340
- Issue date Mar 25, 2025
- H. Lundbeck A/S
- Cheryl A. Grice
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Halogenation of complex organic compounds
- Patent number 12,252,714
- Issue date Mar 18, 2025
- Regents of the University of Michigan
- David H. Sherman
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for treating neurological disorders
- Patent number 12,239,637
- Issue date Mar 4, 2025
- Rush University Medical Center
- Kalipada Pahan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Therapeutic agent for inflammatory diseases, autoimmune diseases, f...
- Patent number 12,239,643
- Issue date Mar 4, 2025
- Meiji Seika Pharma Co., Ltd.
- Natsuki Ishida
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
PAPD5 inhibitors and methods of use thereof
- Patent number 12,171,755
- Issue date Dec 24, 2024
- Children's Medical Center Corporation
- Suneet Agarwal
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bile acid recycling inhibitors for treatment of hypercholemia and c...
- Patent number 12,145,959
- Issue date Nov 19, 2024
- Shire Human Genetic Therapies, Inc.
- Bronislava Gedulin
- Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMA...
Information Patent Grant
Compositions comprising macrocycle derivatives incorporating bridge...
- Patent number 12,139,481
- Issue date Nov 12, 2024
- Southwestern Oklahoma State University
- Timothy J. Hubin
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Treatment and detection of inherited neuropathies and associated di...
- Patent number 12,083,168
- Issue date Sep 10, 2024
- University of Miami
- Stephan L. Zuchner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bicyclic heterocycles as FGFR inhibitors
- Patent number 12,083,124
- Issue date Sep 10, 2024
- Incyte Corporation
- Oleg Vechorkin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Substituted 1H-pyrazolo[4,3-c]pyridines and derivatives as EGFR inh...
- Patent number 12,064,421
- Issue date Aug 20, 2024
- Boehringer Ingelheim International GmbH
- Harald Engelhardt
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treatment
- Patent number 12,016,859
- Issue date Jun 25, 2024
- BOW RIVER LLC
- Sundar Srinivasan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors
- Patent number 11,998,545
- Issue date Jun 4, 2024
- Array Biopharma Inc.
- Steven W. Andrews
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treatment
- Patent number 11,974,998
- Issue date May 7, 2024
- BOW RIVER LLC
- Sundar Srinivasan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods for treating cholestasis
- Patent number 11,918,578
- Issue date Mar 5, 2024
- MIRUM PHARMACEUTICALS, INC.
- Thomas Jaecklin
- G01 - MEASURING TESTING
Information Patent Grant
Compositions and use of varenicline for treating dry eye
- Patent number 11,911,380
- Issue date Feb 27, 2024
- Oyster Point Pharma, Inc.
- Douglas Michael Ackermann
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and use of varenicline for treating dry eye
- Patent number 11,903,942
- Issue date Feb 20, 2024
- Oyster Point Pharma, Inc.
- Douglas Michael Ackermann
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and use of varenicline for treating dry eye
- Patent number 11,903,941
- Issue date Feb 20, 2024
- Oyster Point Pharma, Inc.
- Douglas Michael Ackermann
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and use of varenicline for treating dry eye
- Patent number 11,903,943
- Issue date Feb 20, 2024
- Oyster Point Pharma, Inc.
- Douglas Michael Ackermann
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treatment
- Patent number 11,857,548
- Issue date Jan 2, 2024
- BOW RIVER LLC
- Sundar Srinivasan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treating cancer
- Patent number 11,801,245
- Issue date Oct 31, 2023
- BOW RIVER LLC
- Sundar Srinivasan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compounds and pharmaceutical uses thereof
- Patent number 11,779,561
- Issue date Oct 10, 2023
- SyneuRx International (Taiwan) Corp.
- Guochuan Emil Tsai
- A23 - FOODS OR FOODSTUFFS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
Information Patent Grant
KDM1A inhibitors for the treatment of disease
- Patent number 11,773,068
- Issue date Oct 3, 2023
- Imago Biosciences, Inc.
- Hugh Y. Rienhoff
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Muscarinic acetylcholine M1 receptor antagonists
- Patent number 11,752,149
- Issue date Sep 12, 2023
- Pipeline Therapeutics, Inc.
- Yifeng Xiong
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treatment
- Patent number 11,730,724
- Issue date Aug 22, 2023
- BOW RIVER LLC
- Sundar Srinivasan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods for modulating the endothelial barrier
- Patent number 11,723,910
- Issue date Aug 15, 2023
- University of South Florida
- Jerome William Breslin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Halogenation of complex organic compounds
- Patent number 11,692,176
- Issue date Jul 4, 2023
- Regents of the University of Michigan
- David H. Sherman
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method for inhibiting virus infection and replication
- Patent number 11,679,102
- Issue date Jun 20, 2023
- Chang Gung University
- Shin-Ru Shih
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
COMPOUNDS, COMPOSITIONS, AND METHODS
- Publication number 20250171462
- Publication date May 29, 2025
- Nico Therapeutics, Inc.
- Lydia A. Auch
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING RENAL DIS...
- Publication number 20250170116
- Publication date May 29, 2025
- OSAKA UNIVERSITY
- Ryu NAGATA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CBL-B INHIBITOR, COMPOSITIONS COMPRISING A CBL-B INHIBITOR IN A MET...
- Publication number 20250161278
- Publication date May 22, 2025
- HOTSPOT THERAPEUTICS, INC.
- Fang WANG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS
- Publication number 20250129021
- Publication date Apr 24, 2025
- Interdict Bio, Inc.
- David Gygi
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PHARMACEUTICAL COMPOSITIONS COMPRISING MARALIXIBAT AND USES THEREOF
- Publication number 20250114310
- Publication date Apr 10, 2025
- Mirum Pharmaceuticals, Inc.
- Parag VED
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMBINATION THERAPY FOR TREATING ABNORMAL CELL GROWTH
- Publication number 20250099467
- Publication date Mar 27, 2025
- VERASTEM, INC.
- Sanjib CHOWDHURY
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS
- Publication number 20250091989
- Publication date Mar 20, 2025
- Interdict Bio, Inc.
- David Gygi
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREP...
- Publication number 20250084078
- Publication date Mar 13, 2025
- GENFLEFT THERAPEUTICS (SHANGHAI) INC.
- Jichen ZHAO
- C07 - ORGANIC CHEMISTRY
Information Patent Application
INHIBITORS OF SARS-COV-2
- Publication number 20250084091
- Publication date Mar 13, 2025
- THE TEXAS A&M UNIVERSITY SYSTEM
- James C. Sacchettini
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING HEART FAI...
- Publication number 20250073229
- Publication date Mar 6, 2025
- OSAKA UNIVERSITY
- Ryu NAGATA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
HETEROCYCLIC AMIDES AND METHODS OF USING THE SAME
- Publication number 20250066389
- Publication date Feb 27, 2025
- Rgenta Therapeutics, Inc.
- Travis T. Wager
- C07 - ORGANIC CHEMISTRY
Information Patent Application
INHIBITORS OF TRPC6 FOR TREATING FOCAL SEGMENTAL GLOMERULOSCLEROSIS
- Publication number 20250057829
- Publication date Feb 20, 2025
- Boehringer Ingelheim International GmbH
- Roberto Matias NORDABY
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Heterocyclic Compounds and Methods of Use
- Publication number 20250059205
- Publication date Feb 20, 2025
- Amgen Inc.
- Brian Alan Lanman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
6,6-FUSED HETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS
- Publication number 20250059207
- Publication date Feb 20, 2025
- 858 Therapeutics, Inc.
- Zacharia S. CHERUVALLATH
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BICYCLIC HETEROCYCLES AS FGFR INHIBITORS
- Publication number 20250057852
- Publication date Feb 20, 2025
- INCYTE CORPORATION
- Oleg Vechorkin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TRICYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATIO...
- Publication number 20250051321
- Publication date Feb 13, 2025
- Shanghai Jemincare Pharmaceutical Co., Ltd.
- Gang DENG
- C07 - ORGANIC CHEMISTRY
Information Patent Application
5,6,7,8-TETRAHYDRO-2,6-NAPHTHYRIDINE DERIVATIVES AS CANCER THERAPEU...
- Publication number 20250051361
- Publication date Feb 13, 2025
- VRise Therapeutics, Inc.
- Prashant Kashinath BHAVAR
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Substituted Pyrazolopyridines
- Publication number 20250051363
- Publication date Feb 13, 2025
- Neuro3 Therapeutics, Inc.
- Mark Seefeld
- C07 - ORGANIC CHEMISTRY
Information Patent Application
SOS1 Inhibitor With Pyrido-Fused Six-Membered Ring Structure
- Publication number 20250042857
- Publication date Feb 6, 2025
- HAIHE BIOPHARMA CO., LTD.
- Dongsheng LI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMBINATION THERAPY FOR TREATMENT OF CANCER
- Publication number 20250041313
- Publication date Feb 6, 2025
- CITY OF HOPE
- Ravi Salgia
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
1,4-DIHETEROCYCLIC SUBSTITUTED AROMATIC RING OR AROMATIC HETEROCYCL...
- Publication number 20250034116
- Publication date Jan 30, 2025
- BeBetter Med Inc.
- Xiong CAI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE PARP INHIBITOR AND USE...
- Publication number 20250034168
- Publication date Jan 30, 2025
- XIZANG HAISCO PHARMACEUTICAL CO., LTD.
- Yao LI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS OF TREATMENT
- Publication number 20250032482
- Publication date Jan 30, 2025
- Bow River LLC
- Sundar SRINIVASAN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DIAZABICYCLOOCTANE DERIVATIVES USEFUL AS MATRIX METALLOPROTEINASE I...
- Publication number 20250026761
- Publication date Jan 23, 2025
- VASA THERAPEUTICS SPÓLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA
- Benjamin Anthony Pratt
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF
- Publication number 20250019380
- Publication date Jan 16, 2025
- Relay Therapeutics, Inc.
- Alessandro BOEZIO
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CBL-B INHIBITORS AND METHODS OF USE THEREOF
- Publication number 20250011318
- Publication date Jan 9, 2025
- ARCUS BIOSCIENCES, INC.
- Srikanth Kumar Gangam
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
6-SUBSTITUTED INDOLE COMPOUNDS
- Publication number 20250002471
- Publication date Jan 2, 2025
- GILEAD SCIENCES, INC.
- Stephen E. Ammann
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Compounds for the Degradation of EGFR Kinase
- Publication number 20240425523
- Publication date Dec 26, 2024
- BEIGENE SWITZERLAND GMBH
- Huaqing Liu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PARG INHIBITORY COMPOUNDS
- Publication number 20240425498
- Publication date Dec 26, 2024
- FORX THERAPEUTICS AG
- Ulrich Luecking
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
LURBINECTEDIN AND ATEZOLIZUMAB COMBINATIONS
- Publication number 20240415834
- Publication date Dec 19, 2024
- Pharma Mar, s.a.
- Luis Gonzaga Paz-Ares Rodriguez
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Spiro-condensed pyrazines or piperazines

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Methods of treatment

Trabectedin composition

Pharmaceutical compositions comprising maralixibat and uses thereof

Pyrazole MAGL inhibitors

Halogenation of complex organic compounds

Compositions and methods for treating neurological disorders

Therapeutic agent for inflammatory diseases, autoimmune diseases, f...

PAPD5 inhibitors and methods of use thereof

Bile acid recycling inhibitors for treatment of hypercholemia and c...

Compositions comprising macrocycle derivatives incorporating bridge...

Treatment and detection of inherited neuropathies and associated di...

Bicyclic heterocycles as FGFR inhibitors

Substituted 1H-pyrazolo[4,3-c]pyridines and derivatives as EGFR inh...

Methods of treatment

Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors

Methods of treatment

Methods for treating cholestasis

Compositions and use of varenicline for treating dry eye

Compositions and use of varenicline for treating dry eye

Compositions and use of varenicline for treating dry eye

Compositions and use of varenicline for treating dry eye

Methods of treatment

Methods of treating cancer

Compounds and pharmaceutical uses thereof

KDM1A inhibitors for the treatment of disease

Muscarinic acetylcholine M1 receptor antagonists

Methods of treatment

Compositions and methods for modulating the endothelial barrier

Halogenation of complex organic compounds

Method for inhibiting virus infection and replication

Patents Applicationslast 30 patents

COMPOUNDS, COMPOSITIONS, AND METHODS

PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING RENAL DIS...

CBL-B INHIBITOR, COMPOSITIONS COMPRISING A CBL-B INHIBITOR IN A MET...

SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS

PHARMACEUTICAL COMPOSITIONS COMPRISING MARALIXIBAT AND USES THEREOF

COMBINATION THERAPY FOR TREATING ABNORMAL CELL GROWTH

SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS

FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREP...

INHIBITORS OF SARS-COV-2

PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING HEART FAI...

HETEROCYCLIC AMIDES AND METHODS OF USING THE SAME

INHIBITORS OF TRPC6 FOR TREATING FOCAL SEGMENTAL GLOMERULOSCLEROSIS

Heterocyclic Compounds and Methods of Use

6,6-FUSED HETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS

BICYCLIC HETEROCYCLES AS FGFR INHIBITORS

TRICYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATIO...

5,6,7,8-TETRAHYDRO-2,6-NAPHTHYRIDINE DERIVATIVES AS CANCER THERAPEU...

Substituted Pyrazolopyridines

SOS1 Inhibitor With Pyrido-Fused Six-Membered Ring Structure

COMBINATION THERAPY FOR TREATMENT OF CANCER

1,4-DIHETEROCYCLIC SUBSTITUTED AROMATIC RING OR AROMATIC HETEROCYCL...

NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE PARP INHIBITOR AND USE...

METHODS OF TREATMENT

DIAZABICYCLOOCTANE DERIVATIVES USEFUL AS MATRIX METALLOPROTEINASE I...

PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF

CBL-B INHIBITORS AND METHODS OF USE THEREOF

6-SUBSTITUTED INDOLE COMPOUNDS

Compounds for the Degradation of EGFR Kinase

PARG INHIBITORY COMPOUNDS

LURBINECTEDIN AND ATEZOLIZUMAB COMBINATIONS