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wherein the nucleic acid is delivered as a 'naked' nucleic acid
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A61K48/0016
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HUMAN NECESSITIES
A61
Medical science
A61K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A61K48/00
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases Gene therapy
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A61K48/0016
wherein the nucleic acid is delivered as a 'naked' nucleic acid
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Patents Grants
last 30 patents
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Patent Grant
Compositions and methods for modulating FMR1 expression
Patent number
11,819,554
Issue date
Nov 21, 2023
University of Massachusetts
Michael R. Green
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Using DREADD for neuronal modulation in treating neuronal diseases
Patent number
11,771,778
Issue date
Oct 3, 2023
Fadi Assaf
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Treatments for retinal disease
Patent number
11,766,487
Issue date
Sep 26, 2023
4D MOLECULAR THERAPEUTICS INC.
David H. Kirn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Optimized factor VIII genes
Patent number
11,753,461
Issue date
Sep 12, 2023
Bioverativ Therapeutics Inc.
Siyuan Tan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Gene therapy for haploinsufficiency
Patent number
11,730,828
Issue date
Aug 22, 2023
The Regents of the University of California
Nadav Ahituv
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Motor neuron-specific expression vectors
Patent number
11,642,423
Issue date
May 9, 2023
Salk Institute for Biological Studies
Neal Dilip Amin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Treatments for retinal disease
Patent number
11,576,983
Issue date
Feb 14, 2023
4D MOLECULAR THERAPEUTICS INC.
David H. Kirn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lyophilized pharmaceutical compositions for naked DNA gene therapy
Patent number
11,554,179
Issue date
Jan 17, 2023
Helixmith Co., Ltd.
Byeong Seon Chang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
DNA-binding domain of CRISPR system, non-fucosylated and partially...
Patent number
11,548,937
Issue date
Jan 10, 2023
Zumutor Biologics Inc.
Bhargav Prasad
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Wound healing through sirt1 overexpression
Patent number
11,529,417
Issue date
Dec 20, 2022
Northwestern University
Guillermo A. Ameer
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Compositions and methods for treating cancer with anti-CD33 immunot...
Patent number
11,464,801
Issue date
Oct 11, 2022
LENTIGEN TECHNOLOGY, INC.
Rimas Orentas
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Treating metastatic cancer and model systems for metastatic disease
Patent number
11,464,874
Issue date
Oct 11, 2022
Memorial Sloan Kettering Cancer Center
Karuna Ganesh
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Transgenic mouse expressing amyloid precursor protein that has olfa...
Patent number
11,459,570
Issue date
Oct 4, 2022
The General Hospital Corporation
Mark William Albers
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Adeno-associated virus variant capsids and methods of use thereof
Patent number
11,419,949
Issue date
Aug 23, 2022
4D MOLECULAR THERAPEUTICS INC.
David H. Kirn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and systems for noninvasive control of brain cells and rela...
Patent number
11,400,168
Issue date
Aug 2, 2022
California Institute of Technology
Mikhail G. Shapiro
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for improving viral vector efficiency
Patent number
11,371,061
Issue date
Jun 28, 2022
Genethon
Saliha Majdoul
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Adeno-associated virus variant capsids and methods of use thereof
Patent number
11,364,308
Issue date
Jun 21, 2022
4D MOLECULAR THERAPEUTICS INC.
David H. Kirn
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
DNA antibody constructs and method of using same
Patent number
11,278,619
Issue date
Mar 22, 2022
The Trustees of the University of Pennsylvania
David B. Weiner
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Pharmaceutical composition for inhibiting resistance against antica...
Patent number
11,246,882
Issue date
Feb 15, 2022
Pusan National University Industry-University Cooperation Foundation
Yuseok Moon
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Method for treating peripheral vascular disease using hepatocyte gr...
Patent number
11,219,667
Issue date
Jan 11, 2022
Helixmith Co., Ltd.
Jae-Gyun Jeong
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Poly(histidine)-based micelles for complexation and delivery of pro...
Patent number
11,213,594
Issue date
Jan 4, 2022
Poseida Therapeutics, Inc.
Paiman Peter Ghoroghchian
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Tumor suppressor TET1 and uses thereof
Patent number
11,207,340
Issue date
Dec 28, 2021
The Chinese University of Hong Kong
Qian Tao
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Modulation of exon recognition in pre-mRNA by interfering with the...
Patent number
11,208,657
Issue date
Dec 28, 2021
Academisch Ziekenhuis Leiden
Judith C. Van Deutekom
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Compositions and methods for selective inhibition of grainyhead-lik...
Patent number
11,207,426
Issue date
Dec 28, 2021
University of Massachusetts
Gyongyi Szabo
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Method of using adeno-associated virus with variant capsid
Patent number
11,179,477
Issue date
Nov 23, 2021
4D MOLECULAR THERAPEUTICS INC.
David H. Kirn
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Adeno-associated virus variant capsids and methods of use thereof
Patent number
11,167,041
Issue date
Nov 9, 2021
4D MOLECULAR THERAPEUTICS INC.
David H. Kirn
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
RNA for use in the treatment of ligament or tendon lesions
Patent number
11,065,346
Issue date
Jul 20, 2021
ethris GmbH
Günther Hasenpusch
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Overexpression of FOXC1 to treat corneal vascularization
Patent number
11,001,618
Issue date
May 11, 2021
Northwestern University
Tsutomu Kume
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Immunostimulating vector system
Patent number
10,994,027
Issue date
May 4, 2021
Provecs Medical GmbH
Frank Schnieders
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods and compositions for nucleic acid and protein payload delivery
Patent number
10,975,388
Issue date
Apr 13, 2021
LIGANDAL, INC.
Andre Ronald Watson
B82 - NANO-TECHNOLOGY
Patents Applications
last 30 patents
Information
Patent Application
OPTIMIZED FACTOR VIII GENES
Publication number
20240124555
Publication date
Apr 18, 2024
Bioverativ Therapeutics Inc.
Siyuan TAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHOD OF DELIVERING MRNA IN VIVO
Publication number
20240115731
Publication date
Apr 11, 2024
PCI BIOTECH AS
Anders HØGSET
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF
Publication number
20240117347
Publication date
Apr 11, 2024
WAVE LIFE SCIENCES LTD.
David Charles Donnell Butler
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ADENO-ASSOCIATED VIRUS CAPSIDS AND ENGINEERED LIGAND-GATED ION CHAN...
Publication number
20240108760
Publication date
Apr 4, 2024
TRAMES BIO, INC.
Annahita KERAVALA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS OF PRECISE GENOME EDITING BY IN SITU CUT AND PASTE (ICAP)
Publication number
20240100184
Publication date
Mar 28, 2024
Rowan University
Ping Jiang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ADENO-ASSOCIATED VIRUS VARIANT CAPSIDS WITH IMPROVED RETINAL TRANSD...
Publication number
20240066145
Publication date
Feb 29, 2024
4D MOLECULAR THERAPEUTICS INC.
David H. KIRN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CLOSED-ENDED DNA VECTORS AND USES THEREOF FOR EXPRESSING PHENYLALAN...
Publication number
20240026374
Publication date
Jan 25, 2024
GENERATION BIO CO.
Leah Yu Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR NUCLEIC ACID AND PROTEIN PAYLOAD DELIVERY
Publication number
20240026375
Publication date
Jan 25, 2024
LIGANDAL, INC.
Andre WATSON
B82 - NANO-TECHNOLOGY
Information
Patent Application
USING DREADD FOR NEURONAL MODULATION IN TREATING NEURONAL DISEASES
Publication number
20240009324
Publication date
Jan 11, 2024
Fadi ASSAF
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND FORMULATIONS FOR GENE THERAPY, AND FOR COMBINING GENE T...
Publication number
20240009325
Publication date
Jan 11, 2024
PriZm, LLC
Samuel REFETOFF
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENE THERAPY FOR HAPLOINSUFFICIENCY
Publication number
20230293729
Publication date
Sep 21, 2023
The Regents of the University of California
Nadav Ahituv
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
MOTOR NEURON-SPECIFIC EXPRESSION VECTORS
Publication number
20230277690
Publication date
Sep 7, 2023
Salk Institute for Biological Studies
Neal Dilip AMIN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ADENO-ASSOCIATED VIRUS VECTOR FOR DWARF OPEN READING FRAME
Publication number
20230241249
Publication date
Aug 3, 2023
The Board of Regents of the University of Texas System
Eric N. OLSON
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Compositions and Methods for Treating Cancer with Anti-CD33 Immunot...
Publication number
20230241103
Publication date
Aug 3, 2023
Lentigen Technology, Inc.
Rimas J. Orentas
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS FOR INCREASING PLATELET COUNT BY INHIBITING BILIVERDIN IXBE...
Publication number
20230233712
Publication date
Jul 27, 2023
The Research Foundation for the State University of New York
Wadie F. BAHOU
G01 - MEASURING TESTING
Information
Patent Application
COMPOSITIONS AND METHODS FOR REPROGRAMMING SKIN TISSUE TO HAVE INSU...
Publication number
20230218780
Publication date
Jul 13, 2023
THE TRUSTEES OF INDIANA UNIVERSITY
Chandan K. SEN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENE THERAPY AND TARGETED DELIVERY OF CONJUGATED COMPOUNDS
Publication number
20230201374
Publication date
Jun 29, 2023
Ionis Pharmaceuticals, Inc.
Frank Rigo
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TREATMENT OF LIVER CANCER OR LIVER FIBROSIS
Publication number
20230190955
Publication date
Jun 22, 2023
Baylor College of Medicine
E. LYNN ZECHIEDRICH
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TREATING METASTATIC CANCER AND MODEL SYSTEMS FOR METASTATIC DISEASE
Publication number
20230190963
Publication date
Jun 22, 2023
Memorial Sloan-Kettering Cancer Center
Karuna Ganesh
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND SYSTEMS FOR NONINVASIVE CONTROL OF BRAIN CELLS AND RELA...
Publication number
20230158171
Publication date
May 25, 2023
California Institute of Technology
Mikhail SHAPIRO
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOSITIONS AND METHODS FOR EXPRESSING FACTOR IX FOR HEMOPHILIA B...
Publication number
20230149563
Publication date
May 18, 2023
Regeneron Pharmaceuticals, Inc.
Leah Sabin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR IMPROVING VIRAL VECTOR EFFICIENCY
Publication number
20230117384
Publication date
Apr 20, 2023
Genethon
Saliha MAJDOUL
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
DELIVERY OF COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES
Publication number
20230104113
Publication date
Apr 6, 2023
Flagship Pioneering Innovations VI, LLC.
Avak KAHVEJIAN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
NON-VIRAL DNA VECTORS AND USES THEREOF FOR EXPRESSING PHENYLALANINE...
Publication number
20230024354
Publication date
Jan 26, 2023
Douglas Anthony Kerr
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DNA ANTIBODY CONSTRUCTS AND METHOD OF USING SAME
Publication number
20230023093
Publication date
Jan 26, 2023
David B. Weiner
G01 - MEASURING TESTING
Information
Patent Application
TREATMENTS FOR RETINAL DISEASE
Publication number
20230001018
Publication date
Jan 5, 2023
4D MOLECULAR THERAPEUTICS INC.
David H. KIRN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENE EDITING USING A MODIFIED CLOSED-ENDED DNA (CEDNA)
Publication number
20220290186
Publication date
Sep 15, 2022
GENERATION BIO CO.
Robert M. Kotin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS OF TREATING AND DIAGNOSING EPILEPSY
Publication number
20220143219
Publication date
May 12, 2022
Angelique BORDEY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
LYMPHANGIOGENESIS-PROMOTING AGENTS
Publication number
20220088141
Publication date
Mar 24, 2022
AnGes, Inc.
RYUICHI MORISHITA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND THE P...
Publication number
20220090128
Publication date
Mar 24, 2022
Institut National de la Sante et de la Recherche Medicale (INSERM)
Helene Monique PUCCIO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...