Claims
- 1. A compound of the formula ##STR20## and a pharmaceutically acceptable base salt thereof, wherein R.sub.1 is selected from the group consisting of hydrogen, acetyl, methyl, fluoro, chloro, bromo and methoxy; R.sub.2 is selected from the group consisting of phenyl and mono- and disubstituted phenyl wherein said substituents are selected from the group consisting of chloro and fluoro; and R.sub.3 is selected from the group consisting of alkyl having one to four carbon atoms and phenyl.
- 2. A compound of claim 1, wherein R.sub.2 is selected from the group consisting of phenyl and mono- and disubstituted phenyl wherein said substituent is selected from the group consisting of chloro and fluoro; and R.sub.3 is phenyl.
- 3. The compound of claim 2, wherein R.sub.1 is acetyl and R.sub.2 is 4-chlorophenyl.
- 4. The compound of claim 2, wherein R.sub.1 is chloro and R.sub.2 is phenyl.
- 5. A compound of claim 1, wherein R.sub.2 is 2,4-dichlorophenyl and R.sub.3 is alkyl having one to four carbon atoms.
- 6. The compound of claim 5, wherein R.sub.1 is hydrogen and R.sub.3 is t-butyl.
- 7. A method of treating an inflammatory disease in a mammalian subject, which comprises administering to said mammalian subject an inflammatory disease treating amount of a compound selected from claim 1.
- 8. An antiflammatory composition, which comprises a pharmaceutically acceptable carrier and an effective antiflammatory amount of a compound selected from claim 1, and wherein the weight-ratio of the pharmaceutically acceptable carrier to said compound is in the range of from 1:4 to 20:1.
CROSS REFERENCE TO RELATED APPLICATION
This application is a continuation-in-part of copending application Ser. No. 753,200, filed July 9, 1985.
US Referenced Citations (5)
Non-Patent Literature Citations (1)
Entry |
Capuano et al., Chemische Berichte, 105, 2539 (1972). |
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
753200 |
Jul 1985 |
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