Claims
- 1. A compound of the formula ##STR21## where R.sub.1, R.sub.2, and R.sub.3 = C.sub.1 -C.sub.3 alkyl, C.sub.2 -C.sub.3 alkenyl, or two of R.sub.1, R.sub.2, and R.sub.3 may be joined to form a cycloalkyl or cycloalkenyl group; and its suitable pharmaceutical salts;
- provided that the total number of carbon atoms of R.sub.1 + R.sub.2 + R.sub.3 does not exceed 5.
- 2. The compounds of claim 1 wherein R.sub.1, R.sub.2, and R.sub.3 independently = C.sub.1 -C.sub.3 alkyl.
- 3. The compound of claim 1 which is 1-tert-butyl-3-(3-oxo-1-cyclohexen-1-yl)urea.
- 4. The compound of claim 1 which is 1-tert-amyl-3-(3-oxo-1-cyclohexen-1-yl)urea.
- 5. The compound of claim 1 which is 1-(1-methylcyclopentyl)-3-(3-oxo-1-cyclohexen-1-yl)urea.
- 6. A method of treating hypertension in a warm-blooded animal which comprises administering to the warm-blooded animal an effective antihypertensive amount of a compound of claim 1.
- 7. A method of treating hypertension in a warm-blooded animal which comprises administering to the warm-blooded animal an effective antihypertensive amount of a compound of claim 2.
- 8. A method of treating hypertension in a warm-blooded animal which comprises administering to the warm-blooded animal an effective antihypertensive amount of the compound of claim 3.
- 9. A method of treating hypertension in a warm-blooded animal which comprises administering to the warm-blooded animal an effective antihypertensive amount of the compound of claim 4.
- 10. A method of treating hypertension in a warm-blooded animal which comprises administering to the warm-blooded animal an effective antihypertensive amount of the compound of claim 5.
- 11. A pharmaceutical composition comprising a pharmaceutically suitable carrier and an effective antihypertensive amount of a compound of claim 1.
- 12. A pharmaceutical composition comprising a pharmaceutically suitable carrier and an effective antihypertensive amount of a compound of claim 2.
- 13. A pharmaceutical composition comprising a pharmaceutically suitable carrier and an effective antihypertensive amount of the compound of claim 3.
- 14. A pharmaceutical composition comprising a pharmaceutically suitable carrier and an effective antihypertensive amount of the compound of claim 4.
- 15. A pharmaceutical composition comprising a pharmaceutically suitable carrier and an effective antihypertensive amount of the compound of claim 5.
CROSS-REFERENCE TO RELATED APPLICATION
This application is a continuation-in-part of our copending application Ser. No. 525,445, filed Nov. 20, 1974, which in turn is a continuation-in-part of our application Ser. No. 461,697, filed Apr. 17, 1974, both now abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
3385693 |
Cuckenbaugh |
May 1968 |
|
3701807 |
Chupp |
Oct 1972 |
|
Continuation in Parts (2)
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Number |
Date |
Country |
Parent |
525445 |
Nov 1974 |
|
Parent |
461697 |
Apr 1974 |
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