Claims
- 1. A compound of the formula: ##STR64##where R.sub.1, R.sub.2 and R.sub.3 are C.sub.1 -C.sub.3 alkyl, or C.sub.2 -C.sub.3 alkenyl, with the provisos that the total number of carbon atoms of R.sub.1 plus R.sub.2 plus R.sub.3 does not exceed 5 ##STR65##R.sub.4 is H or CH.sub.3 with the proviso that when R.sub.4 is CH.sub.3, X is -CH.sub.2 CH.sub.2 -; and its sodium, potassium, or calcium salts.
- 2. The compound of claim 1 wherein R.sub.1, R.sub.2, and R.sub.3 are C.sub.1 -C.sub.3 alkyl.
- 3. The compound of claim 2 which is 1-tert-butyl-3-(4,5-dihydro-3-thienyl)urea S,S-dioxide.
- 4. The compound of claim 2 which is 1-tert-amyl-3-(4,5-dihydro-3-thienyl)urea S,S-dioxide.
- 5. The compound of claim 2 which is 1-tert-amyl-3-(4-methyl-4,5-dihydro-3-thienyl)urea S,S-dioxide.
- 6. A method of treating hypertension in a warm-blooded animal comprising administering to the warm-blooded animal an effective antihypertensive amount of a compound of claim 1.
- 7. A method of treating hypertension in a warm-blooded animal comprising administering to the warm-blooded animal an effective antihypertensive amount of a compound of claim 2.
- 8. A method of treating the hypertension in a warm-blooded animal comprising administering to the warm-blooded animal an effective antihypertensive amount of a compound of claim 3.
- 9. A method of treating hypertension in a warm-blooded animal comprising administering to the warm-blooded animal an effective antihypertensive amount of a compound of claim 4.
- 10. A method of treating hypertension in a warm-blooded animal comprising administering to the warm-blooded animal an effective antihypertensive amount of a compound of claim 5.
- 11. A pharmaceutical composition comprising a suitable pharmaceutical carrier and an effective antihypertensive amount of a compound of claim 1.
- 12. A pharmaceutical composition comprising a suitable pharmaceutical carrier and an effective antihypertensive amount of a compound of claim 2.
- 13. A pharmaceutical composition comprising a suitable pharmaceutical carrier and an effective antihypertensive amount of a compound of claim 3.
- 14. A pharmaceutical composition comprising a suitable pharmaceutical carrier and an effective antihypertensive amount of a compound of claim 4.
- 15. A pharmaceutical composition comprising a suitable pharmaceutical carrier and an effective antihypertensive amount of a compound of claim 5.
CROSS-REFERENCE TO RELATED APPLICATION
This application is a continuation-in-part of my copending application Ser. No. 461,699, filed Apr. 17, 1974 now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
3489773 |
Neeff et al. |
Jan 1970 |
|
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
461699 |
Apr 1974 |
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