Claims
- 1. A compound selected from the group consisting of 10-(bis-pyrrolinyl)acridans represented by ##STR4## and a non-toxic pharmaceutically acceptable acid addition salt thereof wherein
- X is a divalent methylene radical represented by the formula --C(Z.sub.1 Z.sub.3)--, wherein Z.sub.1 and Z.sub.2 are independently selected from hydrogen or straight chain lower alkyl of from 1 to 4 carbon atoms inclusive;
- Y represents hydrogen, trifluoromethyl, halogen, lower alkyl of from 1 to 4 carbon atoms inclusive or lower alkoxy of 1 to 4 carbon atoms inclusive; and
- R represents hydrogen or straight chain lower alkyl of 1 to 4 carbon atoms inclusive.
- 2. A compound according to claim 1 being a member selected from the group consisting of 10-[1-(1-pyrrolin-2-yl)-2-pyrrolin-2-yl]acridan or a pharmaceutically acceptable non-toxic acid addition salt thereof.
- 3. A compound according to claim 1 being a member selected from the group consisting of 9,9-dimethyl-10-[1-(1-pyrrolin-2-yl)-2-pyrrolin-2-yl]acridan or a pharmaceutically acceptable non-toxic acid addition salt thereof.
- 4. A compound according to claim 1 being a member selected from the group consisting of 9,9-dimethyl-10-[5-methyl-1-(5-methyl-1-pyrrolin-2-yl)-2-pyrrolin-2-yl]acridan or a pharmaceutically acceptable non-toxic acid addition salt thereof.
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a division of copending application Ser. No. 521,618 filed Nov. 6, 1974, and now U.S. Pat. No. 3,946,004, which is a continuation-in-part of then copending application Ser. No. 336,845 filed Feb. 28, 1973, and now abandoned, which is a continuation-in-part of then copending application Ser. No. 147,667, filed May 27, 1971, now U.S. Pat. No. 3,719,671.
US Referenced Citations (3)
Non-Patent Literature Citations (1)
Entry |
Moskoukina et al., Chemical Abstracts, vol. 73, 14,649n, (1970). |
Divisions (1)
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Number |
Date |
Country |
Parent |
521618 |
Nov 1974 |
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Continuation in Parts (2)
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Number |
Date |
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336845 |
Feb 1973 |
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Parent |
147667 |
May 1971 |
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