Claims
- 1. An antidepressive and stimulating pharmaceutical composition comprising an antidepressively and stimulating effective amount of a compound having the formula I ##SPC7##
- wherein R.sub.1 represents hydrogen or the hydroxy group, R.sub.2 and R.sub.3 represent hydrogen or alkyl groups having 1 to 3 carbon atoms, R.sub.4 and R.sub.5 represent hydrogen, and A represents the direct bond, an alkylene radical having 1 to 3 carbon atoms, or together with ##EQU1## the 1-methyl-4-piperidyl radical, or one of its pharmaceutically acceptable addition salts with an inorganic or organic acid, together with a diluent and/or carrier.
- 2. The composition of claim 1, comprising a compound of the formula I, wherein R.sub.1, R.sub.4 and R.sub.5 represent hydrogen, and R.sub.2, R.sub.3 and A have the meanings defined in claim 1, or of one of its pharmaceutically acceptable addition salts with an inorganic or organic acid, together with a diluent and/or carrier.
- 3. The composition of claim 1, comprising compound of the formula I, wherein R.sub.1 is the hydroxy group, R.sub.2, R.sub.3 and A have the meanings defined in claim 1, and R.sub.4 and R.sub.5 stand for hydrogen, or of one of its pharmaceutically acceptable addition salts with an inorganic or organic acid, together with a diluent and/or carrier.
- 4. The composition of claim 1, comprising N,N-dimethyl-11-hydroxy-1,1a,6,10b-tetrahydro-1,6-methano-dibenzo[a,e]cyclopropa[c]cycloheptene-11-ethylamine-hydrochloride, together with a diluent and/or carrier.
- 5. The method of producing an antidepressive effect in a warm-blooded animal which comprises administering to said mammal in antidepressively effective amount of a compound of the formula I given in claim 1, wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and A have the meanings defined in claim 1 or of one of its pharmaceutically acceptable addition salts with an inorganic or organic acid.
Priority Claims (1)
Number |
Date |
Country |
Kind |
10215/72 |
Jul 1972 |
CH |
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Parent Case Info
This is a division of application Ser. No. 376,670, filed July 5, 1973, now U.S. Pat. No. 3,883,537.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
3883537 |
Schroter |
May 1975 |
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Non-Patent Literature Citations (3)
Entry |
Cioranescu et al., Rev. Roum. Chim. 14 (7), pp. 911-27 (1969). |
Cristol et al., J. Am. Chem. Soc. 90 (20), pp. 5564-5571 (1968). |
Ioan et al., Tetrahedron Letters 38, pp. 3383-3386 (1965). |
Divisions (1)
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Number |
Date |
Country |
Parent |
376670 |
Jul 1973 |
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