Claims
- 1. A 1,2-dithiole derivative of the formula: ##STR11## wherein Het represents pyridazin-3-yl or pyridazin-4-yl, or pyridazin-3-yl or pyridazin-4-yl substituted by alkyl of 1 through 4 carbon atoms, mercapto, dialkylamino having 1 through 4 carbon atoms in each alkyl, or pyrrolidin-1-yl, and R represents alkyl of 1 through 4 carbon atoms.
- 2. A dithiole derivative according to claim 1 wherein Het represents pyridazin-3-yl or pyridazin-4-yl, or pyridazin-3-yl or pyridazin-4-yl substituted by alkyl of 1 through 4 carbon atoms, dialkylamino having 1 through 4 carbon atoms in each alkyl or pyrrolidin-1-yl, and R represents an alkyl radical of 1 through 4 carbon atoms.
- 3. A 1,2-dithiole derivative according to claim 1 which is 4-methyl-5-(pyridazin-3-yl)-1,2-dithiole-3-thione.
- 4. A 1,2-dithiole derivative according to claim 1 which is 4-ethyl-5-(pyridazin-3-yl)-1,2-dithiole-3-thione.
- 5. A 1,2-dithiole derivative according to claim 1 which is 4-methyl-5-(pyridazin-4-yl)-1,2-dithiole-3-thione.
- 6. A 1,2-dithiole derivative according to claim 1 which is 4-butyl-5-(pyridazin-3-yl)-1,2-dithiole-3-thione.
- 7. A 1,2-dithiole derivative according to claim 1 which is 5-(6-dimethylaminopyridazin-3-yl)-4-methyl-1,2-dithiole-3-thione.
- 8. A pharmaceutical composition which comprises a 1,2-dithiole derivative as claimed in claim 1 in association with one or more compatible and pharmaceutically acceptable diluents or adjuvants.
Priority Claims (2)
Number |
Date |
Country |
Kind |
76 03604 |
Feb 1976 |
FRX |
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76 38901 |
Dec 1976 |
FRX |
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Parent Case Info
This is a division of application Ser. No. 766,966, filed Feb. 9, 1977.
Foreign Referenced Citations (1)
Number |
Date |
Country |
1526768 |
Nov 1963 |
FRX |
Non-Patent Literature Citations (3)
Entry |
Bottcher et al., Chem. Ber. 84, pp. 458-463 (1951). |
Legrand et al., Bull. Soc. Chim. (France) pp. 79-83, (1955). |
The Chemistry of Heterocyclic Compounds, vol. 21, 1st part, "Multi-Sulfur and Sulfur and Oxygen Five and Six Membered Heterocycles", pp. 382-384, Interscience Publishers, (1966). |
Divisions (1)
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Number |
Date |
Country |
Parent |
766966 |
Feb 1977 |
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