Claims
- 1. A compound of the formula: ##STR44## wherein R.sub.4 is hydrogen or lower alkyl; R.sub.1 is lower alkyl; R.sub.6 is hydroxy, lower alkanoyloxy, benzoyloxy, tetrahydropyranyloxy, benzyloxy, benzhydryloxy, trimethylsilyloxy, trityloxy or 4-methoxy-5,6-dihydro-2H-pyranyloxy;
- or enantiomers or racemates thereof.
- 2. The compound of claim 1 where R.sub.6 is hydroxy.
- 3. The compound of claim 2 wherein R.sub.4 is lower alkyl.
- 4. The compound of claim 2 wherein said compound is nat. (2,E)-11R-methyl-16,16-difluoro-15R-hydroxy-9-oxoprosta-5,13-dienoic acid.
CROSS REFERENCE TO RELATED APPLICATIONS
This application is a continuation-in-part of U.S. application Ser. No. 745,257 filed Dec. 8, 1976 now U.S. Pat. No. 4,112,225, which in turn is a continuation-in-part of U.S. application Ser. No. 683,576 filed May 5, 1976 now abandoned, Holland, Jernow and Rosen which is also a continuation-in-part of U.S. application Ser. No. 480,458 filed July 18, 1974 now U.S. Pat. No. 4,052,446, Holland, Jernow and Rosen which in turn is a continuation-in-part of U.S. patent application Ser. No. 386,117, Holland, Jernow and Rosen filed Aug. 6, 1973 now abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4029698 |
Woessner et al. |
Jun 1977 |
|
4057571 |
Grudzinskas |
Nov 1977 |
|
Foreign Referenced Citations (2)
Number |
Date |
Country |
2437622 |
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DEX |
2638827 |
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DEX |
Continuation in Parts (4)
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Number |
Date |
Country |
Parent |
745257 |
Dec 1976 |
|
Parent |
683576 |
May 1976 |
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Parent |
480458 |
Jul 1974 |
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Parent |
386117 |
Aug 1973 |
|