Claims
- 1. A compound having the formula: ##STR29## and the pharmaceutically acceptable acid addition salts thereof wherein R is styryl, chlorostyryl, phenyl, or mono- or disubstituted phenyl wherein each substitutent is chloro, bromo, fluoro, trifluoromethyl, phenyl, alkoxy or alkyl, said alkoxy or alkyl having from 1 to 4 carbon atoms; R.sub.1 and R.sub.2 are each hydrogen, chloro, bromo, fluoro, trifluoromethyl, methoxy or methyl; X is nitrogen; and R.sub.3 and R.sub.4 when taken separately are each alkyl having from 1 to 4 carbon atoms and when taken together with the nitrogen to which they are attached form piperidino, pyrrolidino, morpholino, piperazino, 4-benzylpiperazino or 4-alkylpiperazino, said alkyl having from 1 to 4 carbon atoms.
- 2. The compound of claim 1 wherein R.sub.3 and R.sub.4 when taken together with the nitrogen to which they are attached form a 4-methyl piperazino ring.
- 3. The compound of claim 2 wherein R.sub.1 and R.sub.2 are each hydrogen and R is 3-trifluoromethylphenyl.
- 4. The compound of claim 2, wherein R.sub.1 and R.sub.2 are each hydrogen and R is 3,4-dichlorophenyl.
- 5. A compound of claim 1 wherein R is monosubstituted phenyl wherein each substituent is chloro, trifluoromethyl or methoxy, disubstituted phenyl wherein each substitutent is chloro; R.sub.1 and R.sub.2 are each hydrogen; and R.sub.3 and R.sub.4 taken together with the nitrogen to which they are attached form a 4-alkylpiperazino ring said alkyl having from 1 to 4 carbon atoms.
CROSS-REFERENCE TO RELATED APPLICATION
This application is a division of application Ser. No. 495,375 filed Aug. 7, 1974 and now U.S. Pat. No. 4,002,623 as issued Jan. 11, 1977.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
3004978 |
Hunger et al. |
Oct 1961 |
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Divisions (1)
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Number |
Date |
Country |
Parent |
495375 |
Aug 1974 |
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