Claims
- 1. A process for preparing a compound having the formula II: ##STR19## wherein R.sub.5 ', R.sub.6 ' and R.sub.7 ' are each hydrogen, halogen, hydroxy, lower alkyl, or lower alkoxy; R.sub.8 ' is hydrogen or lower alkyl and X' is a bromide, chloride or iodide salt, which comprises treating a compound of the formula III: ##STR20## wherein R.sub.5 R.sub.6 and R.sub.7 are each hydrogen, halogen, hydroxy, lower alkyl or lower alkoxy; and R.sub.8 is hydrogen or lower alkyl with a hyrohalide acid and a lower alkanoic acid, compound II retaining said alkoxy groups only when compound III: (a) contains a halogen substituent on the phenyl para to alkoxy group or (b) said alkoxy group is ortho to the carbonyl and R.sub.8 is lower alkyl ortho to the N-oxide.
- 2. A process according to claim 1 wherein, in an additional step, compound II is treated with a lower alkanoic acid anhydride to convert hydroxyl substituents to the corresponding lower alkanoyl substituents.
- 3. A process according to claim 1 wherein, in an additional step, compound II is alkylated to convert the hydroxyl substituents to the corresponding lower alkoxy substituents.
Parent Case Info
This is a division of application Ser. No. 611,281 filed Sept. 8, 1972, now U.S. Pat. No. 3,983,237 granted Sept. 28, 1976.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
3983237 |
Connor et al. |
Sep 1976 |
|
Non-Patent Literature Citations (4)
Entry |
Boekelheide et al., J. Org. Chem. vol. 26, pp. 3802 to 3805 (1961). |
Adams et al., J. Am. Chem. Soc. vol. 79, pp. 2236 to 2239 (1957). |
Boekelheide et al., J. Am. Chem. Soc. vol. 80, pp. 2217 to 2220 (1958). |
Osborne et al., J. Heterocyclic Chemistry, vol. 1, pp. 138 to 140 (1964). |
Divisions (1)
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Number |
Date |
Country |
Parent |
611281 |
Sep 1975 |
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