Claims
- 1. A compound of the formula ##STR9## wherein R.sub.1 is chlorine, bromine, fluorine or methyl;
- R.sub.2 and R.sub.3 are each hydrogen, chlorine or methyl;
- R.sub.4 is hydrogen, methyl or ethyl; and
- R.sub.5 and R.sub.6, together with each other and the nitrogen atom to which they are attached, are morpholino, piperazino or N-methyl-piperazino;
- or a non-toxic, pharmaceutically acceptable acid addition salt thereof.
- 2. A compound of claim 1, which is 2-[N-(1,3-dimorpholino-isopropyl)-amino]-4-(2,6-dichlorophenyl)-2-imidazoline or a non-toxic, pharmaceutically acceptable acid addition salt thereof.
- 3. A compound of claim 1, which is 2-[N-(1,3-dimorpholino-isopropyl)-amino]-4-(2,4,6-trimethyl-phenyl)-2-imidazoline or a non-toxic, pharmaceutically acceptable acid addition salt thereof.
- 4. A compound of claim 1, which is 2-[N(1,3-bis-(N'-methyl-piperazino)-isopropyl)-amino]-4-(2,6-dimethyl-phenyl)-2-imidazoline or a non-toxic, pharmaceutically acceptable acid addition salt thereof.
- 5. An antithrombotic pharmaceutical dosage unit composition consisting essentially of an inert pharmaceutical carrier and an effective antithrombotic amount of a compound of claim 1.
- 6. The method of inhibiting thrombocyte aggregation in a warm-blooded animal in need thereof, which comprises enterally or parenterally administering to said animal an effective antithrombotic amount of a compound of claim 1.
Priority Claims (1)
Number |
Date |
Country |
Kind |
2525725 |
Jun 1975 |
DEX |
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Parent Case Info
This is a continuation-in-part of copending application Ser. No. 692,325, filed June 3, 1976, now U.S. Pat. No. 4,058,616, granted Nov. 11, 1977.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4058616 |
Kummer et al. |
Nov 1977 |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
692325 |
Jun 1976 |
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