Claims
- 1. The method comprising reacting a compound having Formula I ##STR15## in which R.sub.1 is any straight or branched chain alkyl group having 1 to 10 carbon atoms, and X is a halogen with ArMgX in which Ar is any aryl group and X is a halogen wherein a compound having Formula II ##STR16## is produced.
- 2. The claim 1 method in which Ar is a phenyl, a napthyl or a 9-fluorenyl group.
- 3. The claim 1 or claim 2 method in which X is chlorine or bromine or fluorine.
- 4. The claim 1 or claim 2 method in which R.sub.1 is a methyl, ethyl, propyl, isopropyl, butyl, isobutyl, hexyl, isohexyl, octyl or isooctyl group.
- 5. A method for synthesizing a compound having Formula I ##STR17## which R.sub.1 is any straight or branched chain alkyl group having 1 to 10 carbon atoms, and X is a halogen which comprises:
- (i) reacting a malonic acid diester with an alkali metal hydride and a 2-halobenzylhalide to produce a compound having Formula IV ##STR18## wherein R.sub.2 and R.sub.3 are the same or optionally different straight or branched chain alkyl groups having 1 to 10 carbon atoms;
- (ii) saponifying said compound having Formula IV to produce a compound having Formula V ##STR19## in which Z is an alkali metal; (iii) converting said compound having Formula V to a compound having Formula VII ##STR20## (iv) reacting said compound having Formula VII with SOCl.sub.2 to produce a compound having Formula VIII ##STR21## (v) reacting said compound having Formula VIII with aluminum chloride to produce a compound having Formula IX ##STR22## (vi) reacting said compound having Formula IX with sodium borohydride to produce a compound having Formula X ##STR23## and (vii) reacting said compound having the Formula X with paratoluene sulfuric acid to produce said compound having Formula I.
- 6. The claim 5 method in which:
- (i) said malonic acid diester of step (i) has the Formula III ##STR24## and (ii) the alkali metal hydride of step (i) is sodium hydride, and the halobenzylhalide of step (i) is 2-chlorobenzyl chloride.
- 7. A method which comprises:
- (i) reacting an alkali metal salt of a fatty acid having 1 to 10 carbon atoms with an alkali metal hydride to produce a first reaction mixture containing an intermediate compound; and
- (ii) combining said step (i) reaction mixture with a 2-halobenzylhalide to convert said intermediate compound into a compound having the Formula XIV ##STR25##
- 8. The method which comprises reacting a compound having the formula: in which R.sub.1 is a straight or branched chain alkyl group having one to ten carbon atoms with a naphthyl magnesium bromide wherein a reaction mixture containing a compound having the Formula ##STR26## in which R.sub.1 is a straight or branched chain alkyl group is produced.
- 9. The claim 8 method in which R.sub.1 in the compound having the formula: ##STR27## is methyl or ethyl.
- 10. A method which comprises reacting 7-chloro-2-methylindene with naphthyl magnesium bromide, wherein a reaction mixture containing 7-naphthyl 2-methylindene is produced.
- 11. The claim 10 method in which said 7-naphthyl-2-methylindene is separated from said reaction mixture.
- 12. A method which comprises
- (i) reacting a compound having Formula I ##STR28## in which R.sub.1 is any straight or branched chain alkyl group having 1 to 10 carbon atoms, and X is a halogen with ArMgX in which Ar is any aryl group and X is a halogen
- wherein a compound having Formula II ##STR29## is produced; and (ii) converting said compound of Formula II produced in step (i) to a compound having the formula XIV ##STR30## wherein Q.sub.1 and Q.sub.2 are the same or different Formula II compounds, Y is an alkyl group, M is a group IV metal and Z is a halogen.
- 13. The claim 12 method wherein Y is methyl and Z is chlorine.
Parent Case Info
This application is a continuation-in-part of application Ser. No. 08/795,019 filed Feb. 5, 1997, now U.S. Pat. No. 5,789,634.
PCT Information
Filing Document |
Filing Date |
Country |
Kind |
102e Date |
371c Date |
PCT/US98/02345 |
2/5/1998 |
|
|
9/22/1998 |
9/22/1998 |
Publishing Document |
Publishing Date |
Country |
Kind |
WO98/33752 |
8/6/1998 |
|
|
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
5789634 |
Sullivan et al. |
Aug 1998 |
|
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
795019 |
Feb 1997 |
|