Claims
- 1. A compound of the formula: ##SPC1##
- wherein:
- R is hydrogen, halogen, C.sub.1 -C.sub.6 alkanoyloxy, C.sub.1 -C.sub.6 alkoxy, C.sub.1 -C.sub.6 alkylthio, C.sub.1 -C.sub.5 alkyl or thiocyanato;
- R.sup.1 is a hydroxy group, nitro-oxy group, C.sub.1-5 alkanoyloxy group or C.sub.1-5 alkanoyloxy group substituted by at least one halogen atom or carboxy or amino group;
- R.sup.2 is hydrogen or methyl;
- R.sup.3 is oxygen or ##EQU1## R.sup.4 is chlorine, bromine or iodine atom, a p-toluene sulphonyloxy or methanesulphonyloxy group or a C.sub.1-6 alkoxy, C.sub.5-6 cycloalkoxy, phenyl C.sub.1-6 alkoxy or phenoxy group or such a hydrocarbyloxy group substituted by at least one halogen atom or carboxyl, C.sub.1-6 alkoxy carbonyl, C.sub.1-6 -alkoxy or cyano group;
- R.sup.5 is hydrogen or C.sub.1 -C.sub.6 alkyl
- R.sup.6 is hydroxy or R.sup.4 and R.sup.6 together are --O-- to form an epoxy group joining the 20- and 21- positions.
- 2. The compound of claim 1 which is 20.beta.,21-epoxy-3.alpha.-hydroxy-5.alpha.-pregnan-11-one.
- 3. The compound of claim 1 which is 20.beta.,21-epoxy-3.alpha.-hydroxy-16.alpha.-methyl-5.alpha.-pregnan-11-one.
- 4. The compound of claim 1 which is 20.beta.,21-epoxy-3.alpha.-hydroxy-5.alpha.-pregnane.
Priority Claims (1)
Number |
Date |
Country |
Kind |
60065/70 |
Dec 1970 |
UK |
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Parent Case Info
This application is a division of application Ser. No. 208,961, filed Dec. 16, 1971, and now U.S. Pat. No. 3,882,151.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
3822298 |
Clayton et al. |
Jul 1974 |
|
Divisions (1)
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Number |
Date |
Country |
Parent |
208961 |
Dec 1971 |
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