Claims
- 1. A compound of the formula ##STR23## where n is 2; A is ##STR24## where X in each occurrence is independently hydrogen, halogen, loweralkyl, hydroxy, nitro, loweralkoxy, amino, cyano, trifluoromethyl or methylthio; Y in each occurrence is independently hydrogen, halogen, loweralkyl, hydroxy, nitro, loweralkoxy, amino, cyano, trifluoromethyl or methylthio; m is 1 or 2; k is 1 or 2; R.sub.1 and R.sub.2 are independently hydrogen, loweralkyl, ##STR25## or aryl except that when R.sub.1 is ##STR26## or aryl, R.sub.2 is hydrogen, or alternatively R.sub.1 +R.sub.2 taken together with the carbon atom to which they are attached form a cyclopentane, cyclohexane, cycloheptane, pyran, thiopyran, indan or piperidine ring; R.sub.3 and R.sub.4 are independently hydrogen or loweralkyl, or alternatively R.sub.3 +R.sub.4 taken together with the carbon atom to which they are attached form a cyclopentane, cyclohexane, cycloheptane, pyran, thiopyran, pyrrolidine or piperidine ring, the term aryl signifying an unsubstituted phenyl group or a phenyl group substituted with 1,2 or 3 substituents each of which being independently loweralkyl, loweralkoxy, hydroxy, halogen, loweralkythio, cyano, amino or trifluoromethyl, or a pharmaceutically acceptable acid addition salt thereof.
- 2. The compound according to claim 1, where R.sub.1 =R.sub.2 =CH.sub.3.
- 3. The compound according to claim 1, where A is ##STR27##
- 4. The compound according to claim 2, where A is ##STR28##
- 5. The compound according to claim 1, which is 1,1-dioxo-3-(4-(1-(6-fluorobenzo[b]thiophene-3-yl)piperazin-4-yl)butyl)-2,5,5-trimethyl-4-thiazolidinone maleate. maleate.
Parent Case Info
This is a continuation-in-part application of a prior application, Ser. No. 713,247, filed Jun. 7, 1991, now U.S. Pat. No. 5,136,037 which is a division of a prior application, Ser. No. 487,328, filed Mar. 2, 1990, now U.S. Pat. No. 5,037,984, which is a continuation of a prior application, Ser. No. 430,688, filed Oct. 31, 1989, now U.S. Pat. No. 4,933,453, which is a continuation-in-part application of a prior application, Ser. No. 123,622, filed Nov. 20, 1987, now abandoned.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
4933453 |
Hrib et al. |
Jun 1990 |
|
5037984 |
Hrib et al. |
Aug 1991 |
|
5041445 |
Hrib et al. |
Aug 1991 |
|
Divisions (1)
|
Number |
Date |
Country |
Parent |
487328 |
Mar 1990 |
|
Continuations (1)
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Number |
Date |
Country |
Parent |
430688 |
Oct 1989 |
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Continuation in Parts (2)
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Number |
Date |
Country |
Parent |
713247 |
Jun 1991 |
|
Parent |
123622 |
Nov 1987 |
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