Claims
- 1. A compound of the formula II ##STR28## or a salt thereof, in which: X is halogen,
- n is 0, 1, 2 or 3;
- T is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.6 alkenyl, C.sub.3 -C.sub.6 alkynyl, C.sub.3 -C.sub.6 cycloalkyl or substituted or unsubstituted phenyl, benzyl or phenethyl;
- Z is CN, CO--A or CS--A,
- A is hydrogen, halogen, OR.sub.1, SR.sub.2 and N(R.sub.3)R.sub.4 ; R.sub.1 to R.sub.4 are hydrogen, a substituted or unsubstituted, open-chain, saturated or unsaturated hydrocarbon radical containing not more than 8 carbon atoms, a substituted or unsubstituted cyclic, saturated or unsaturated hydrocarbon radical containing not more than 10 carbon atoms, substituted or unsubstituted benzyl or phenethyl, a substituted or unsubstituted alkanoyl group containing not more than 8 carbon atoms, a substituted or unsubstituted benzoyl group or a substituted or unsubstituted heterocyclyl radical; or
- R.sub.3 and R.sub.4, together with the nitrogen atom to which they are bonded, are a 5- or 6-membered, substituted or unsubstituted heterocyclic radical having 1-3 heteroatoms O, S and/or N;
- with the exception of the compound, in which Z is COOC.sub.2 H.sub.5, n is 0 and T is hydrogen.
- 2. A compound according to claim 1, in which:
- Z is fluorine;
- n is 0 or 1;
- T is hydrogen or C.sub.1 -C.sub.6 alkyl;
- Z is CN or CO--A;
- A is OR.sub.1, SR.sub.2, or N(R.sub.3)R.sub.4 ; and in which
- R.sub.1,
- R.sub.2 and R.sub.3 are hydrogen, C.sub.1 -C.sub.8 alkyl, which is unsubstituted for substituted by 1-5 halogen atoms, C.sub.3 -C.sub.6 cycloalkyl, C.sub.1 -C.sub.4 alkoxy, phenoxy, benzyloxy C.sub.1 -C.sub.4 acyloxy, benzoyloxy, hydroxyl, nitro, cyano, C.sub.1 -C.sub.4 alkanoyl, benzoyl, carboxyl, C.sub.1 -C.sub.4 alkoxycarbonyl, benzyloxycarbonyl, amino, C.sub.1 -C.sub.4 alkylamino, C.sub.1 -C.sub.4 dialkylamino or heterocyclyl, C.sub.3 -C.sub.6 alkenyl which is unsubstituted or substituted by 1-5 halogen atoms, C.sub.3 -C.sub.6 alkynyl, C.sub.3 -C.sub.6 cycoalkyl, C.sub.1 -C.sub.4 alkanoyl, phenyl, benzyl or phenethyl, the phenyl rings of which are unsubstituted or substituted once to three times by halogen, hydroxyl, C.sub.1 -C.sub.4 alkyl, halogeno-C.sub.1 -C.sub.2 alkyl, C.sub.1 -C.sub.2 alkoxy, halogeno-C.sub.1 -C.sub.2 alkoxy or nitro, or naphthyl, benzoyl or heterocyclyl, which are unsubstituted or substituted once to three times in an identical or different manner by halogen, C.sub.1 -C.sub.2 alkyl, halogenomethyl or nitro, or
- R.sub.4 is hydrogen, C.sub.1 -C.sub.6 alkyl, phenyl or benzyl; or
- R.sub.3 and R.sub.4, together with the nitrogen atom to which they are bonded, are a 5- or 6-membered ring with 1-2 heteroatoms O,S and/or N, where the rings mentioned are unsubstituted or substituted once or twice in an identical or different manner by halogen; C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.2 alkoxycarbonyl.
- 3. A compound according to claim 2, in which
- A is OR.sub.1 or SR.sub.2 ; and
- R.sub.1 and R.sub.2 are hydrogen, C.sub.1 -C.sub.6 alkyl, which is unsubstituted or substituted by 1-3 halogen atoms, C.sub.3 -C.sub.6 cycloalkyl, or C.sub.1 -C.sub.2 alkoxy, C.sub.3 -C.sub.4 alkenyl, which is unsubstituted or substituted by 1-3 halogen atoms, C.sub.3 -C.sub.4 alkynyl, C.sub.3 -C.sub.6 cycloalkyl, or phenyl, benzyl or phenethyl, the phenyl rings of which are unsubstituted or substituted once or twice by halogen, hydroxyl, C.sub.1 -C.sub.4 alkyl, halogeno-C.sub.1 -C.sub.2 alkyl, C.sub.1 -C.sub.2 alkoxy, halogeo-C.sub.1 -C.sub.2 alkoxy or nitro.
- 4. A compound according to claim 3, in which:
- n is 0;
- T is hydrogen or methyl;
- Z is CO--A,
- A is OR.sub.1 ; and
- R.sub.1 is hydrogen, C.sub.1 -C.sub.6 alkyl, which is unsubstituted or substituted by 1-3 halogen atoms, or C.sub.1 -C.sub.2 alkoxy, C.sub.3 -C.sub.6 cycloalkyl, or phenyl, benzyl or phenethyl, the phenyl rings of which are unsubstituted or substituted once or twice by halogen, hydroxyl, C.sub.1 -C.sub.4 alkyl, halogeno-C.sub.1 -C.sub.2 alkyl, C.sub.1 -C.sub.2 alkoxy, halogeno-C.sub.1 -C.sub.2 alkoxy or nitro.
Priority Claims (1)
Number |
Date |
Country |
Kind |
3637/95 |
Dec 1995 |
CHX |
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Parent Case Info
This application is a divisional of Ser. No. 09/042,357, filed Mar. 13, 1998, now U.S. Pat. No. 5,847,147, which is a divisional of Ser. No. 08/770,353, filed Dec. 20, 1996, now U.S. Pat. No. 5,770,758.
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Entry |
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Gupta RR, et al. (1980) "Studies on Phenothiazines. Part 7(1). Synthesis of 3-Substituted 2-Aminobenzenethiols and their Conversion into Phenothiazines" J. Heterocyclic Chem. vol. 17, pp. 1325-1327. |
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Divisions (2)
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Number |
Date |
Country |
Parent |
042357 |
Mar 1998 |
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Parent |
770353 |
Dec 1996 |
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