Claims
- 1. A compound of the formula: ##STR20## wherein R.sup.1 is isopropyl, an allyl, propargyl, or a cycloalkyl having 3 to 8 carbon atoms, and R.sup.2 is an alkyl selected from the group consisting of n-heptyl, n-octyl, n-nonyl and n-decyl.
- 2. The compound according to claim 1 wherein the NO.sub.2 substituent is in the ortho-position.
- 3. The compound according to claim 1 wherein R.sup.2 is n-heptyl, n-octyl, or n-nonyl.
- 4. The compound according to claim 1 wherein R.sup.1 is cyclopropyl or cyclopentyl.
- 5. The compound according to claim 4 wherein R.sup.2 is n-heptyl, n-octyl or n-nonyl.
- 6. The compound according to claim 1 wherein R.sup.1 is an allyl or propargyl and R.sup.2 is n-heptyl, n-octyl or n-nonyl.
- 7. A pharmaceutical composition having vasodilatory activity for the prophylaxis and treatment of circulatory diseases, which comprises as an active ingredient an effective amount of a compound of the formula: ##STR21## wherein R.sup.1 is isopropyl, an allyl, propargyl, or a cycloalkyl having 3 to 8 carbon atoms, and R.sup.2 is an alkyl selected from the group consisting of n-heptyl, n-octyl, n-nonyl and n-decyl, in admixture with a pharmaceutically acceptable carrier or diluent.
- 8. The composition according to claim 7 wherein the NO.sub.2 substituent is in the ortho-position.
- 9. The pharmaceutical composition according to claim 7 wherein R.sup.2 is n-heptyl, n-octyl or n-nonyl.
- 10. The pharmaceutical composition according to claim 7 wherein R.sup.1 is cyclopropyl or cyclopentyl.
- 11. The pharmaceutical composition according to claim 10 wherein R.sup.2 is n-heptyl, n-octyl or n-nonyl.
- 12. The pharmaceutical composition according to claim 7 wherein R.sup.1 is allyl or propargyl and R.sup.2 is n-heptyl, n-octyl or n-nonyl.
Priority Claims (1)
Number |
Date |
Country |
Kind |
60-235909 |
Oct 1985 |
JPX |
|
Parent Case Info
This application is a file wrapper continuation of U.S. application Ser. No. 920,124, filed Oct. 17, 1986 now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4472411 |
Hatayama et al. |
Sep 1984 |
|
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Continuations (1)
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Number |
Date |
Country |
Parent |
920124 |
Oct 1986 |
|