Claims
- 1. A compound of the formula ##STR7## in which n is 1 or 2 and R is a straight-chained, saturated alkyl group containing 16 to 18 carbon atoms, steroisomers thereof, and pharmacologically acceptable salts thereof.
- 2. A compound according to claim 1 wherein n is 1.
- 3. A compound according to claim 2 wherein R contains 16 carbon atoms.
- 4. A compound according to claim 2 wherein R contains 18 carbon atoms.
- 5. A compound according to claim 1 selected from the group consisting of (3-hexadecylsulphinyl-2-methoxy-methylpropyl)-(2-trimethylammonioethyl) phosphate, (3-octadecylsulphinyl-2-methoxymethylproply)-(2-trimethylammonioethyl) phosphate and the (+) and (-) entantiomers thereof.
- 6. A compound according to claim 1 wherein n is 2.
- 7. A compound according to claim 6 wherein R contains 16 carbon atoms.
- 8. A compound according to claim 6 wherein R contains 18 carbon atoms.
- 9. A compound according to claim 1 selected from the group consisting of (3-hexadecylsulphonyl-2-methoxy-methylpropyl)-(2-trimethylammonioethyl) phosphate, (3-octadecylsulphonyl-2-methoxymethylproply)-(2-trimethylammonioethyl) phosphate and the (+) and (-) entantiomers thereof.
- 10. A pharmaceutical composition comprising a compound of claim 1 and a pharmaceutically acceptable carrier.
- 11. A pharmaceutical composition according to claim 10 wherein the compound is (3-hexadecanesulphonyl-2-methoxymethylpropyl)-(2-trimethylammonioethyl) phosphate.
- 12. A pharmaceutical composition according to claim 10 wherein the compound is (3-octadecanesulphonyl-2-methoxymethylpropyl)-(2-trimethylammonioethyl) phosphate.
Priority Claims (1)
Number |
Date |
Country |
Kind |
39 06 952.4 |
Mar 1989 |
DEX |
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Parent Case Info
This application is a continuation of application Ser. No. 07/925,407 filed Aug. 10, 1992, now abandoned, which is a continuation of application Ser. No. 07/758,518 filed Sep. 6, 1991, now abandoned, which is a continuation of application Ser. No. 07/486,658 filed Mar. 1, 1990, now abandoned.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
4372949 |
Kodama et al. |
Feb 1983 |
|
4444766 |
Bosies et al. |
Apr 1984 |
|
4492659 |
Bosies et al. |
Jan 1985 |
|
Foreign Referenced Citations (4)
Number |
Date |
Country |
A1-2619715 |
Nov 1977 |
DEX |
A1-2619686 |
Nov 1977 |
DEX |
C3-2009341 |
Sep 1979 |
DEX |
A1-3304870 |
Aug 1984 |
DEX |
Non-Patent Literature Citations (2)
Entry |
Vogler et al., Lipids, vol. 26 No. 12 (1991) (Presented in Tokyo, Japan in May 1989 at 3rd Intern Conf. on Lipids. |
The Merck Manual, 15th Ed. (Rahway, N.J., 1987 Merck and Co.) pp. 1206-1209. |
Continuations (3)
|
Number |
Date |
Country |
Parent |
925407 |
Aug 1992 |
|
Parent |
758518 |
Sep 1991 |
|
Parent |
486658 |
Mar 1990 |
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