Claims
- 1. A 3-deoxy-mycaminosyltylonolide compound of the following formula or its pharmaceutically acceptable salt: ##STR22## wherein X represents an oxygen atom; R.sup.1 represents an alkylsilyl group; and R.sup.2 and R.sup.3 represent hydrogen.
- 2. A pharmaceutical composition having antibacterial activity comprised of an antibacterial effective amount of the compound of claim 1 and a pharmaceutically acceptable carrier.
- 3. The pharmaceutical composition of claim 2 wherein said compound is 3,4'-di-deoxy-23-O-thexyldimethylsilyl-mycaminosyltylonolide.
- 4. A method for inhibiting bacterial activity in a host which comprises administering to said host an antibacterial effective amount of the pharmaceutical composition of claim 2.
- 5. The method of claim 4 wherein said compound is 3,4'-di-deoxy-23-O-thexyldimethylsilyl-mycaminosyltylonolide.
Priority Claims (2)
Number |
Date |
Country |
Kind |
63-146410 |
Jun 1988 |
JPX |
|
1-9160 |
Jan 1989 |
JPX |
|
Parent Case Info
This is a division of application Ser. No. 362,872, filed June 7, 1989, now abandoned.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
4345069 |
Sakakibara et al. |
Aug 1982 |
|
4438109 |
Umezawa et al. |
Mar 1984 |
|
4794173 |
Umezawa et al. |
Dec 1988 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
2221695 |
Sep 1987 |
JPX |
Continuations (1)
|
Number |
Date |
Country |
Parent |
362872 |
Jun 1989 |
|