Claims
- 1. A 3-substituted-2(1H)pyridine-6-carboxylic acid of the general formula ##STR7## wherein R.sub.1 is an aralkyl group of the formula ##STR8## wherein R.sub.2 is hydrogen, a lower alkyl group, or a halogen atom.
- 2. A compound according to claim 1, wherein R.sub.1 is a functional group of the formula ##STR9## wherein R.sub.2 is hydrogen, chlorine, methyl or ethyl.
- 3. A compound according to claim 1, wherein R.sub.1 is the benzyl group.
- 4. A compound according to claim 1, wherein R.sub.1 is the p-chlorobenzyl group.
- 5. A compound according to claim 1, wherein R.sub.1 is the methylbenzyl group.
- 6. A compound according to claim 1, wherein R.sub.1 is the ethylbenzyl group.
- 7. A therapeutic composition of matter for lowering the blood pressure which comprises (i) a therapeutically effective amount of a 3-substituted-2(1H)pyridone-6-carboxylic acid, and (ii) a pharmaceutically acceptable carrier, said 3-substituted-2(1H)pyridone-6-carboxylic acid (i) having the general formula ##STR10## wherein R.sub.1 is an aralkyl group of the formula ##STR11## wherein R.sub.2 is hydrogen, a lower alkyl group, or a halogen atom, and being suspended in said carrier (ii).
- 8. A therapeutic composition of matter according to claim 7, wherein said carrier is a gum arabic solution.
- 9. A therapeutic composition of matter according to claim 7, wherein R.sub.1 is the p-ethylbenzyl group in (i).
Priority Claims (2)
Number |
Date |
Country |
Kind |
50-80102 |
Jun 1975 |
JPX |
|
50-80103 |
Jun 1975 |
JPX |
|
CROSS REFERENCE TO RELATED APPLICATION
This application is a continuation-in-part of copending application Ser. No. 700,340, filed June 28, 1976, now U.S. Pat. No. 4,083,850.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
3355278 |
Weil et al. |
Nov 1967 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
1016676 |
Jul 1974 |
JPX |
Non-Patent Literature Citations (2)
Entry |
Kametani et al., Chemical Abstracts, vol. 74 (1971), 13311e. |
Stetter et al., Chemical Abstracts, vol. 52 (1958), 91290. |
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
700340 |
Jun 1976 |
|