Claims
- 1. A 3,4-dehydropiperidine compound of the formula ##STR11## wherein R.sub.1 is a hydrogen atom or an alkyl group having 1-3 carbon atoms;
- Y is a group of the formula 2 ##STR12## wherein R.sub.2 is a group of the formula --(CH.sub.2).sub.n --C(.dbd.X)--NR.sub.3 R.sub.4, --(CH.sub.2).sub.n --SO.sub.2 --NR.sub.3 R.sub.4, --(CH.sub.2).sub.n --NR.sub.5 --C(.dbd.X)--R.sub.6 or --(CH.sub.2).sub.n --NR.sub.5 --SO.sub.2 --R.sub.6, wherein R.sub.3, R.sub.4 and R.sub.5 independent of each other represent hydrogen or alkyl (1-3C), R.sub.6 is alkyl (1-3C), X represents O or S; and n is 0-4;
- R is hydrogen or alkyl (1-3C),
- and a pharmaceutically acid addition salt thereof.
- 2. A pharmaceutical composition which comprises a 3,4-dehydropiperidine compound defined in claim 1 and a carrier.
- 3. A method of treating migraine in a human patient, said method comprising administering an antimigraine effective amount of a compound as claimed in claim 1 to the patient.
Priority Claims (1)
Number |
Date |
Country |
Kind |
91201855 |
Jul 1991 |
EPX |
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Parent Case Info
This application is a continuation of application Ser. No. 07/911,630, filed Jul. 10, 1992 now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4259338 |
Paioni et al. |
Mar 1981 |
|
Foreign Referenced Citations (4)
Number |
Date |
Country |
0021924 |
Jan 1981 |
EPX |
0303507 |
Feb 1989 |
EPX |
0398413 |
Nov 1990 |
EPX |
2056435 |
Mar 1981 |
GBX |
Non-Patent Literature Citations (2)
Entry |
Paloni et al. CA 93: 132373d, 1980. |
Clark et al. Principles of Psychopharmacology Academic Press, N.Y. London, 1970, pp. 166-167. |
Continuations (1)
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Number |
Date |
Country |
Parent |
911630 |
Jul 1992 |
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