Claims
- 1. A 1,2-diaryl-2-propen-1-one compound of the formula ##STR10## wherein Y represents a 5-substituted-2-pyridinyl, 6-substituted-3-pyridinyl, (6 or 7)-substituted-2-quinolinyl, (6 or 7)-substituted-3-quinolinyl, 5-substituted-2-pyrimidinyl, 2-substituted-5-pyrimidinyl, 5-substituted-2-pyrazinyl, or 6-substituted-3-pyridazinyl moiety, each moiety being substituted in the designated position by one of F, Cl, Br, CN, COQ, CF.sub.3, OR', SR', and OAr;
- X represents Y, phenyl, or phenyl substituted in the 4-position with F, Cl, Br, CN, COQ, R, OR', SR', NO.sub.2, or OAr and/or in the 3-position with F, Cl, Br, CN, R, or OR';
- R represents C.sub.1 -C.sub.3 alkyl, C.sub.2 -C.sub.3 alkenyl, or C.sub.2 -C.sub.3 alkynyl each optionally singly to completely substituted with fluorine or chlorine;
- R' represents C.sub.1 -C.sub.3 alkyl optionally singly to completely substituted with fluorine or chlorine;
- R" represents C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.4 alkenyl, or C.sub.3 -C.sub.4 alkynyl;
- Ar represents phenyl optionally substituted with 1 or 2 compatible substituents selected from F, Cl, Br, CN, COQ, R, OR', SR', and NO.sub.2 ; and
- Q represents OR", SR", NH.sub.2, NHR, or NR".sub.2.
- 2. A compound according to claim 1 wherein X represents substituted phenyl.
- 3. A compound according to claim 2 wherein X represents phenyl substituted in the 4-position with F, Cl, Br, CF.sub.3, and OCF.sub.3, OCF.sub.2 CF.sub.2 H, or SCF.sub.3.
- 4. A compound according to claim 1 wherein each Y moiety is substituted in the designated position by one of F, Cl, Br, CN, CF.sub.3, and OCF.sub.3.
- 5. A compound according to claim 4 wherein X represents phenyl substituted in the 4-position with F, Cl, Br, CF.sub.3, OCF.sub.3, OCF.sub.2 CF.sub.2 H, or SCF.sub.3.
- 6. A compound according to claim 5: 1-(4-fluorophenyl)-2-(5-trifluoromethyl-2-pyridinyl)-2-propen-1-one.
- 7. A compound according to claim 5: 1-(4-chlorophenyl)-2-(5-cyano-2-pyridinyl)-2-propene-1-one.
- 8. A compound according to claim 5: 2-(5-chloro-2-pyrimidinyl)-1-(4-fluorophenyl)-2-propene-1-one.
- 9. A 1,2-diarylethanone compound of the formula ##STR11## wherein Y represents a 5-substituted-2-pyridinyl, 6-substituted-3-pyridinyl, (6 or 7)-substituted-2-quinolinyl, (6 or 7)-substituted-3-quinolinyl, 5-substituted-2-pyrimidinyl, 2-substituted-5-pyrimidinyl, 5-substituted-2-pyrazinyl, or 6-substituted-3-pyridazinyl moiety, each moiety being substituted in the designeted position by one of F, Cl, Br, CN, COQ, CF.sub.3, OR', SR', and OAr;
- X represents Y, phenyl, or phenyl substituted in the 4-position with F, Cl, Br, CN, COQ, R, OR', SR', NO.sub.2, or OAr and/or in the 3-position with F, Cl, Br, CN, R, or OR';
- R represents C.sub.1 -C.sub.3 alkyl, C.sub.2 -C.sub.3 alkenyl, or C.sub.2 -C.sub.3 alkynyl each optionally singly to completely substituted with fluorine or chlorine;
- R' represents C.sub.1 -C.sub.3 alkyl optionally singly to completely substituted with fluorine or chlorine;
- R" represents C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.4 alkenyl, or C.sub.3 -C.sub.4 alkynyl;
- Ar represents phenyl optionally substituted with 1 or 2 compatible substituents selected from F, Cl, Br, CN, COO, R, OR', SR', and NO.sub.2 ; and
- Q represents OR", SR", NH.sub.2, NHR, or NR".sub.2.
- 10. A compound according to claim 9 wherein X represents substituted phenyl.
- 11. A compound according to claim 10 wherein X represents phenyl substituted in the 4-position with F, Cl, Br, CF.sub.3, and OCF.sub.3, OCF.sub.2 CF.sub.2 H, or SCF.sub.3.
- 12. A compound according to claim 9 wherein each Y moiety is substituted in the designated position by one of F, Cl, Br, CN, CF.sub.3, and OCF.sub.3.
- 13. A compound according to claim 12 wherein X represents phenyl substituted in the 4-position with F, Cl, Br, CF.sub.3, OCF.sub.3, OCF.sub.2 CF.sub.2 H, or SCF.sub.3.
- 14. A compound according to claim 13: 1-(4-fluorophenyl)-2-(5-trifluoromethyl-2-pyridinyl)ethanone.
- 15. A compound according to claim 13: 1-(4-chlorophenyl)-2-(5-cyano-2-pyridinyl)ethanone.
- 16. A compound according to claim 13: 2-(5-chloro-2-pyrimidinyl)-1-(4-fluorophenyl)ethanone.
Parent Case Info
This application is a continuation of U.S. Ser. No. 07/684,525, filed Apr. 11, 1991, abandoned.
US Referenced Citations (18)
Foreign Referenced Citations (1)
Number |
Date |
Country |
158103 |
Dec 1982 |
DEX |
Non-Patent Literature Citations (2)
Entry |
Weber et al., Zeitschrift fur Chemie, 1972, 12(4), 132-133. |
Chem Abstr. vol. 108, #112,429 (1988). |
Continuations (1)
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Number |
Date |
Country |
Parent |
684525 |
Apr 1991 |
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