Claims
- 1. A compound of the formula ##STR13## wherein X is hydrogen, chloro or bromo, Y is hydrogen, fluoro or chloro with the proviso that X and Y cannot both be hydrogen and R.sub.1 is selected from the group consisting of a radical of the formula ##STR14## and a radical of the formula ##STR15## wherein R.sub.2 is hydrogen, lower alkyl, hydroxy, amino, monoalkylamio and dialkylamino and R.sub.3 is hydroxy, or amino with the proviso that where R.sub.1 is other than hydrogen then the bonding at the 4,5-position is unsaturated
- and the pharmaceutically acceptable salt thereof.
- 2. A compound of the formula ##STR16## wherein X is hydrogen, chloro or bromo and Y is hydrogen, fluoro or chloro with the proviso that X and Y cannot both be hydrogen and R.sub.2 is selected from the group consisting of hydrogen, lower alkyl, hydroxy, amino, monoalkylamino and dialkylamino
- and the pharmaceutically acceptable salts thereof.
- 3. The compound: 8-chloro-5-(1-amino-2-propyn-3-yl)-1-(2-fluorophenyl)-3H-2-benzazepine and the pharmaceutically acceptable salt thereof.
- 4. The compound of the formula ##STR17## wherein X is chloro, Y is hydrogen, fluoro or chloro and R.sub.1 is a radical of the formula ##STR18## or a radical of the formula ##STR19## wherein R.sub.2 is amino, monoalkylamino or dialkylamino and R.sub.3 is amino.
- 5. The compound of claim 4 wherein R.sub.1 is a radical of the formula ##STR20## and R.sub.2 is as in claim 4.
- 6. The compound: 8-chloro-5-(1-amino-2-propyn-3-yl)-1-phenyl-3H-2-benzazepine and the pharmaceutically acceptable salts thereof.
RELATED APPLICATIONS
This is a continuation of application Ser. No. 251,579, filed Apr. 6, 1981, which is a continuation-in-part of Ser. No. 150,508, filed May 16, 1980, both now abandoned.
Non-Patent Literature Citations (1)
Entry |
Padwa et al., J.A.C.S., 97(16), 4682-91. |
Continuations (1)
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Number |
Date |
Country |
Parent |
251579 |
Apr 1981 |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
150508 |
May 1980 |
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