4-Amino-1,5-substituted-1,5-dihydro-imidazol-2-ones

Information

The present invention relates to compounds of formula I

1. A compound of formula I
2. A compound of claim 1 having formula IA
3. A compound of claim 1, wherein R1 is phenyl substituted by halogen, R2 is phenyl and R4 is benzyl.
4. A compound of claim 3, selected from the group consisting of
5. A compound of claim 1, wherein R1 is phenyl substituted by halogen, R2 is phenyl substituted by lower alkyl and R4 is benzyl.
6. A compound of claim 5, selected from the group consisting of
7. A compound of claim 1, wherein R1 and R2 are phenyl substituted by halogen and R4 is benzyl.
8. A compound of claim 7, selected from the group consisting of
9. A compound of claim 1, wherein R1 is phenyl substituted by halogen, R2 is phenyl substituted by methoxy and R4 is benzyl.
10. A compound of claim 9, which is
11. A compound of claim 1, wherein R1 is phenyl substituted by halogen, R2 is phenyl and R4 is benzyl substituted by halogen.
12. A compound of claim 11, which is
13. A compound of claim 1, wherein R1 is phenyl substituted by halogen, R2 is phenyl and R4 is lower alkyl.
14. A compound of claim 13, selected from the group consisting of
15. A compound of claim 1, wherein R1 is phenyl substituted by halogen, R2 is phenyl and R4 is —CH2-cycloalkyl.
16. A compound of claim 15, which is
17. A pharmaceutical composition comprising a therapeutically effective amount of a compound of formula I
18. The composition of claim 17 wherein the compound is a compound of formula IA
19. A process for preparing a compound of formula I

Number	Date	Country	Kind
06110812.2	Mar 2006	EP	regional