Claims
- 1. A 1- or 2-thio- or thiomethylenenaphthalene derivative of the formula II ##STR7## or a pharmaceutically acceptable catonic salt thereof, wherein n is 0 or 1
- R.sub.5 is hydrogen, bromo, chloro, trifluoromethyl or difluoroethyl;
- R.sub.6 is hydrogen, hydroxy, methoxy or ethoxy; and
- R.sub.7 is hydrogen or R.sub.7 and R.sub.6 are both methyl or ethyl carbonate.
- 2. A 1- or 2-thio- or thiomethylenenaphthalene derivative of claim 1 in which R.sub.5 is trifluoromethyl and R.sub.6 is methoxy.
- 3. A 1- or 2-thio- or thiomethylenenaphthalene derivative of claim 1 in which R.sub.5, R.sub.6, and R.sub.7 are each hydrogen.
- 4. A 1- or 2-thio- or thiomethylenenaphthalene derivative of claim 1 which is 5-[[(2-naphthalenyl)methyl]thio]-2,4-thiazolidinedione.
- 5. A 1- or 2-thio- or thiomethylenenaphthalene derivative of claim 1 which is 5-[[6-methoxy-5-(trifluoromethyl)-2-naphthalenyl]thio]-2,4-thiazolidinedione.
- 6. A 1- or 2-thio- or thiomethylenenaphthalene derivative of claim 1 which is carbonic acid 6-[(2,4-dioxo-5-thiazolidinyl)thio]-2,3-naphthalenediyl diethyl ester.
- 7. A 1- or 2-thio- or thiomethylenenaphthalene derivative of claim 1 which is 5-[(2-naphthalenyl)thio]-2,4-thiazolidinedione.
- 8. A 1- or 2-thio- or thiomethylenenaphthalene derivative of claim 1 which is 5-[(6-hydroxy-2-naphthalenyl)thio]-2,4-thiazolidinedione.
Parent Case Info
This is a division of application Ser. No. 07/428,817 filed Oct. 27, 1989, now U.S. Pat. No. 4,997,948.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4968707 |
Clark |
Nov 1990 |
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Divisions (1)
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Number |
Date |
Country |
Parent |
428817 |
Oct 1989 |
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