Claims
- 1. A compound of the formula: ##STR7## wherein R.sub.1 is
- (a) carboxy or
- (b) --COOR.sub.4, wherein R.sub.4 is C.sub.1 -C.sub.12 alkyl or C.sub.3 -C.sub.4 alkenyl;
- R.sub.2 is
- (a') C.sub.1 -C.sub.6 alkyl, which may be unsubstituted or substituted by C.sub.1 -C.sub.2 alkoxy, or (b') C.sub.3 -C.sub.4 alkenyl;
- R.sub.3 is C.sub.1 -C.sub.4 alkyl; and the salts thereof with pharmaceutically acceptable bases.
- 2. Compound of claim 1, wherein R.sub.1 is carboxy or carbalkoxy of 1 to 6 carbon atoms in the alkoxy group and R.sub.2 is C.sub.1 -C.sub.6 alkyl.
- 3. Compound of claim 2, wherein R.sub.2 is C.sub.1 -C.sub.4 alkyl and R.sub.3 is methyl or propyl.
- 4. Compound of claim 3, wherein R.sub.1 is carboxy.
- 5. 6-carboxy-2'-isopropoxy-5'-ethyl-flavone or a salt thereof, as claimed in claim 1.
- 6. 6-carboxy-2'-isopropoxy-3'-propyl-flavone or a salt thereof, as claimed in claim 1.
- 7. 6-carboxy-2'-isopropoxy-5'-propyl-flavone or a salt thereof, as claimed in claim 1.
- 8. 6-carboxy-2'-isopropoxy-5'-isopropyl-flavone or a salt thereof, as claimed in claim 1.
- 9. 6-carboxy-2'-methoxy-3'-methyl-flavone or a salt thereof, as claimed in claim 1.
- 10. 6-carboxy-2'-methoxy-5'-methyl-flavone or a salt thereof, as claimed in claim 1.
- 11. 6-carboxy-2'-methoxy-3'-propyl-flavone or a salt thereof, as claimed in claim 1.
- 12. 6-carboxy-2'-(2"-ethoxy-ethoxy)-3'-methylflavone or a salt thereof, as claimed in claim 1.
- 13. 6-carboxy-2'-(2"-ethoxy-ethoxy)-5'-methylflavone or a salt thereof, as claimed in claim 1.
- 14. 6-carboxy-2'-isopropoxy-3'-methyl-flavone or a salt thereof, as claimed in claim 1.
- 15. 6-carboxy-2'-isopropoxy-4'-methyl-flavone or a salt thereof, as claimed in claim 1.
- 16. 6-carboxy-2'-isopropoxy-5'-methyl-flavone or a salt thereof, as claimed in claim 1.
Priority Claims (1)
Number |
Date |
Country |
Kind |
28527 A/76 |
Oct 1976 |
ITX |
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CROSS-REFERENCE TO PARENT APPLICATIONS
This application is a continuation-in-part of copending application Ser. No. 660,383 filed on Feb. 23, 1976, now U.S. Pat. No. 4,065,467, issued Dec. 27, 1977, which is, in turn, a continuation of application Ser. No. 536,476, filed on Dec. 26, 1974, now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4065467 |
Doria et al. |
Dec 1977 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
823875 |
Jan 1975 |
BEX |
Non-Patent Literature Citations (3)
Entry |
Shah et al., JACS, 77, 2223 (1955). |
Shah et al., JCS, pp. 2663-2666 (1961). |
Hsu et al., Chem. Abstract, 54, 4553g (1960). |
Continuations (1)
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Number |
Date |
Country |
Parent |
536476 |
Dec 1974 |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
660383 |
Feb 1976 |
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