Claims
- 1. A compound selected from the group consisting of 3-(2-methylbutyl)-8-ethyl-6-thioxanthine, 3-ethyl-8-n-butyl-6-thioxanthine, 3-n-propyl-8-n-butyl-6-thioxanthine, 3-n-propyl-8-n-pentyl-6-thioxanthine, 3-n-propyl-8-cyclopropyl-6-thioxanthine, 3-n-propyl-8-cyclobutyl-6-thioxanthine 3-isobutyl-8-n-butyl-6-thioxanthine 3-n-pentyl-8-ethyl-6-thioxanthine and 3-isopentyl-8-ethyl-6-thioxanthine, and pharmaceutically acceptable salts thereof.
- 2. The compound of claim 1 wherein said compound is 3-(2-methylbutyl)-8-ethyl-6-thioxanthine or a pharmaceutically acceptable salt thereof.
- 3. The compound of claim 1 wherein said compound is 3-ethyl-8-n-butyl-6-thioxanthine or a pharmaceutically acceptable salt thereof.
- 4. The compound of claim 1 wherein said compound is 3-n-propyl-8-n-butyl-6-thioxanthine or a pharmaceutically acceptable salts thereof.
- 5. The compound of claim 1 wherein said compound is 3-n-propyl-8-n-pentyl-6-thioxanthine or a pharmaceutically acceptable salt thereof.
- 6. The compound of claim 1 wherein said compound is 3-n-propyl-8-cyclopropyl-6-thioxanthine or a pharmaceutically acceptable salt thereof.
- 7. The compound of claim 1 wherein said compound is 3-n-propyl-8-cyclopropyl-6-thioxanthine or a pharmaceutically acceptable salt thereof.
- 8. The compound of claim 1 wherein said compound is 3-isobutyl-8-n-butyl-6-thioxanthine or a pharmaceutically acceptable salt thereof.
- 9. The compound of claim 1 wherein said compound is 3-n-pentyl-8-ethyl-6-thioxanthine or a pharmaceutically acceptable salt thereof.
- 10. The compound of claim 1 wherein said compound is 3-isopentyl-8-ethyl-6-thioxanthine or a pharmaceutically acceptable salt thereof.
- 11. A pharmaceutical composition for use in the treatment of chronic obstruction airway disease comprising a 6-thioxanthine or a pharmaceutically acceptable salt thereof according to claim 1 in conjunction with a pharmaceutically acceptable diluent or carrier.
Priority Claims (1)
Number |
Date |
Country |
Kind |
8618931 |
Aug 1986 |
GBX |
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CROSS REFERENCE TO RELATED APPLICATION
This is a continuation-in-part of co-pending application Ser. No. 699,254, filed Feb. 7, 1985, now U.S. Pat. No. 4,710,503.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
3900474 |
Ginger et al. |
Aug 1979 |
|
4546182 |
Kjellin et al. |
Oct 1989 |
|
4710503 |
Hofer |
Dec 1987 |
|
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
699254 |
Feb 1985 |
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