Claims
- 1. A compound having the formula: ##STR6## wherein R.sup.1 is an amino group or a protected amino group having a protected group selected from the group consisting of benzylidene, phenylacetyl, formyl, tertbutoxycarbonyl and trityl, R.sup.2 is a hydrogen atom or a protecting group for a hydroxyl group selected from the group consisting of acetyl and trimethylsilyl, R.sup.3 represents negative charge, a hydrogen atom or a protecting group for a carboxyl group, and n is 0 or 1, and a salt thereof.
- 2. The compound according to claim 1, wherein R.sup.1 is an amino group, a p-chlorobenzylideneamino group, a p-nitrobenzylideneamino group, a formylamino group, a tert-butoxycarbonylamino group, a chloroacetylamino group, a benzyloxycarbonylamino group, a tritylamino group, a benzylamino group, an .alpha.-naphthylideneamino group, a .beta.-naphthylideneamino group, a phenylacetylamino group, a benzylideneamino group or a salicylideneamino group.
- 3. The compound according to claim 1, which is in the form of a solvate.
- 4. The compound according to claim 1, which is 7-amino-3-(5,6-dihydroxy-2-methyl-2-isoindolinium)methyl-3-cephem-4-carboxylate or a salt thereof.
- 5. The compound according to claim 1, which is 7-amino-3-(5,6-dihydroxy-2-methyl-2-isoindolinium)methyl-3-cephem-4-carboxylate hydrochloride or a solvate thereof.
- 6. The compound according to claim 1, which is 7-amino-3-(5,6-dihydroxy-2-methyl-2-isoindolinium)methyl-3-cephem-4-carboxylate dihydrochloride or a solvate thereof.
- 7. The compound according to claim 1, which is p-methoxybenzyl 7-benzylideneamino-3-[5,6-di(trimethylsilyloxy)-2-methyl-2-isoindolinium]methyl-3-cephem-4-carboxylate iodide.
- 8. The compound according to claim 1, which is benzhydryl 7-benzylideneamino-3-[5,6-di(trimethylsilyloxy)-2-methyl-2-isoindolinium]methyl-3-cephem-4-carboxylate iodide.
- 9. The compound according to claim 1, which is 7-phenylacetamido-3-(5,6-dihydroxy-2-methyl-2-isoindolinium)methyl-3-cephem-4-carboxylate.
- 10. The compound according to claim 1, which is p-methoxybenzyl 7-formamido-3-(5,6-dihydroxy-2-methyl-2-isoindolinium)methyl-3-cephem-4-carboxylate iodide.
Priority Claims (3)
Number |
Date |
Country |
Kind |
59-273591 |
Dec 1984 |
JPX |
|
60-171839 |
Aug 1985 |
JPX |
|
61-291431 |
Dec 1986 |
JPX |
|
Parent Case Info
This application is continuation in part of U.S. patent application Ser. No. 06/813,614 filed on Dec. 26, 1985, now 4,677,100.
US Referenced Citations (5)
Non-Patent Literature Citations (2)
Entry |
Burger, A., Medicinal Chemistry, 2nd ed. (1960, Interscience Publishers, Inc.: New York), pp. 42-43. |
McOmie, J., Protective Groups in Organic Chemistry, (1973, Plenum Press: New York), pp. 46-67, 157, 171-175. |
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
813614 |
Dec 1985 |
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