Claims
- 1. A compound having the formula ##STR16## in which R.sub.6 and R.sub.7 form a chain --COCH.dbd.C(COOH)--O--, R.sub.5 and R.sub.8, which may be the same or different, are sterically compatible substituents selected from hydrogen and alkyl having up to 8 carbon atoms, and
- R.sub.g is hydrogen or alkyl having up to 8 carbon atoms,
- and pharmaceutically acceptable salts and ethyl esters thereof.
- 2. A compound according to claim 1, wherein each of R.sub.5, R.sub.8 and R.sub.g, when they are alkyl, contain up to 4 carbon atoms.
- 3. A compound according to claim 1, wherein the --COCH.dbd.C(COOH)--O-- chain is bonded with the --O-- end thereof in position R.sub.7.
- 4. A compound according to claim 1, wherein R.sub.5 and R.sub.8 are selected from hydrogen and propyl.
- 5. A compound according to claim 1, wherein R.sub.g is ethyl.
- 6. 4,6-Dioxo-1-ethyl-10-propyl-4H,6H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid or a pharmaceutically acceptable salt thereof.
- 7. 4,6-Dioxo-10-propyl-4H,6H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid or a pharmaceutically acceptable salt thereof.
- 8. A pharmaceutical composition suitable for the treatment of a condition involving an antibody antigen reaction or a reflex pathway comprising an effective amount of a compound according to claim 1 in combination with a pharmmaceutically acceptable adjuvant, diluent or carrier.
- 9. A composition according to claim 8 comprising less than 80% by weight of active ingredient.
- 10. A composition comprising from 0.01 mg to 50 mg of a compound according to claim 1, as active ingredient, in unit dosage form.
- 11. A method of treatment of a condition involving an antibody antigen reaction or a reflex pathway, which comprises administering an effective amount of a compound according to claim 1 to an animal suffering from such a condition.
Priority Claims (3)
Number |
Date |
Country |
Kind |
18597/77 |
May 1977 |
GBX |
|
48565/77 |
Nov 1977 |
GBX |
|
16168/78 |
Apr 1978 |
GBX |
|
Parent Case Info
This is a continuation of application Ser. No. 946,492, filed Sept. 28, 1978 abandoned which is a CIP of Ser. No. 897,416 filed Apr. 18, 1978 abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
3773769 |
Albrecht et al. |
Nov 1973 |
|
4117134 |
Connor et al. |
Sep 1978 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
073427 |
Mar 1975 |
JPX |
Continuations (1)
|
Number |
Date |
Country |
Parent |
946492 |
Sep 1978 |
|
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
897416 |
Apr 1978 |
|