Claims
- 1. A therapeutic composition for the inhibition of lipolysis in mammals which comprises, as an active ingredient, an effective amount to effect inhibition of lipolysis in said mammals of a member of the formula ##STR7## and pharmaceutically acceptable salts thereof wherein: R.sub.1 is H, alkyl, alkoxy, trihalomethyl, chlorine;
- X is in the 8 position and is O(CH.sub.2).sub.n, or N(CH.sub.2).sub.n ;
- Y is O(CH.sub.2).sub.n, N(CH.sub.2).sub.n ;
- R.sub.2 is monosubstituted or independently disubstituted H, carboxyl or alkylcarboxy;
- Z is 0; and
- n is 0 to 10 inclusive, wherein the alkyl group and the alkyl moieties in alkoxy and alkylcarboxy having from 1 to 7 carbon atoms, in a pharmaceutically acceptable carrier.
- 2. A pharmaceutical composition for the inhibition of lipolysis in mammals which comprises, as an active ingredient, an effective amount of 8-quinolyl-carbanilate in a pharmaceutically acceptable carrier.
- 3. A pharmaceutical composition for the inhibition of lipolysis in mammals which comprises, as an active ingredient, an effective amount of 2-methyl-8-quinolyl carbanilate in a pharmaceutically acceptable carrier.
RELATED APPLICATIONS
This application is a continuation of our copending application, Ser. No. 455,377, filed Jan. 3, 1983, now abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
3538099 |
Rohr et al. |
Nov 1970 |
|
3946016 |
Karsten et al. |
Mar 1976 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
989578 |
Apr 1965 |
GBX |
Non-Patent Literature Citations (2)
Entry |
Somasekhara, Chem. Abst., vol. 70 (1969), 11532w. |
Somasekhara, Current Science 37(19): 551-2, 1968. |
Continuations (1)
|
Number |
Date |
Country |
Parent |
455377 |
Jan 1983 |
|