Claims
- 1. A compound of the Formula (II) ##STR23## wherein R.sub.2 is hydrogen or NH.sub.2, and Ar is (i) phenyl unsubstituted or substituted by halogen, alkyl of from one to four carbons, hydroxy, alkoxy of one to four carbons, or trifluoromethyl, (ii) 2- or 3-thienyl, or (iii) 2- or 3-furanyl.
- 2. A compound of the Formula (III) ##STR24## wherein R.sub.2 is hydrogen or NH.sub.2 and Ar is (i) phenyl unsubstituted or substituted by halogen, alkyl of from one to four carbons, hydroxy, alkoxy of from one to four carbon atoms, or trifluoromethyl, (ii) 2- or 3- thienyl, (iii) 2- or 3- furanyl.
- 3. A process of treating a compound of Formula (II) ##STR25## wherein R.sub.2 is hydrogen or NH.sub.2, and Ar is (i) phenyl unsubstituted or substituted by halogen, alkyl of from one to four carbon atoms, hydroxy, alkoxy of one to four carbon atoms, or trifluoromethyl, (ii) 2- or 3- thienyl, or (iii) 2- or 3- furanyl;
- in a basic solution with sodium dithionite to obtain a compound of the formula (I) ##STR26## wherein R.sub.6 is oxygen and R.sub.8 is amino and R.sub.2 and Ar are as defined as above; and alternatively further a) treating the compound of the formula II as defined above or b) treating the compound of the formula I wherein R.sub.6 is oxygen and R.sub.8 is amino; with hydrogen in the presence of a catalyst to obtain a compound of the formula I wherein R.sub.6 is oxygen and R.sub.8 is hydrogen.
- 4. A process of claim 3 wherein the basis solution is a 1N NaOH solution.
Parent Case Info
This is a divisional of U.S. application Ser. No. 07/478,610, filed Feb. 12, 1990, now U.S. Pat. No. 4,988,702 which is a divisional of U.S. application Ser. No. 07/336,585, filed Apr. 10, 1989, now U.S. Pat. No. 4,923,872, which is a continuation of U.S. application No. 07/117,352, filed Nov. 12, 1987, now abandoned, which is a continuation-in-part of U.S. application Ser. No. 07/059,419, filed June 18, 1987, now abandoned which is a continuation-in-part of U.S. application Ser. No. 06/900,486, filed Aug. 26, 1986, now abandoned.
Non-Patent Literature Citations (1)
Entry |
Modern Synthetic Reactions, 2nd Ed. (1972), pp. 4,8 and 9, Benjamin/Cummings Publ. Co., Menlo Park, Calif. |
Divisions (2)
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Number |
Date |
Country |
Parent |
478610 |
Feb 1990 |
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Parent |
336585 |
Apr 1989 |
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Continuations (1)
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Number |
Date |
Country |
Parent |
117352 |
Nov 1987 |
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Continuation in Parts (2)
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Number |
Date |
Country |
Parent |
59419 |
Jun 1987 |
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Parent |
900486 |
Aug 1986 |
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