Claims
- 1. A compound of the formula ##STR16## wherein R.sub.1 and R.sub.2 are lower alkyl; R.sub.3 is hydrogen, lower alkyl, lower alkoxy, lower alkenyloxy, nitro, halo, amino, lower alkylamino, lower alkanoylamino R.sub.4 is hydrogen, lower alkyl, lower alkenyl, lower alkoxy, lower alkenyloxy, nitro, lower alkanoyloxy, amino, lower alkylamino R.sub.5 is hydrogen, lower alkyl, lower alkenyl, lower alkoxy, lower alkenyloxy, nitro, halo, amino, lower alkanoylamino, lower alkylamino with the proviso that at least one of R.sub.3, R.sub.4 and R.sub.5 is other than hydrogen; with the further proviso that when R.sub.3 or R.sub.5 is halogen, R.sub.4 is other than alkoxy; and R.sub.6 is carboxyl and pharmaceutically acceptable salts thereof.
- 2. The compound of claim 1 wherein R.sub.3, R.sub.4 and R.sub.5 are hydrogen or lower alkyl.
- 3. The compound of claim 2 wherein said compound is 9-(2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid.
- 4. The compound of claim 2 wherein said compound is 9-(2,4,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid.
- 5. The compound of claim 2 wherein said compound is 9-(2,4,6-triisopropyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid.
- 6. The compound of claim 2 wherein said compound is 9-(2,3,4,6-tetramethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid.
- 7. The compound of claim 2 wherein said compound is 9-(pentamethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid.
- 8. The compound of claim 1 wherein at least one of R.sub.3, R.sub.4 or R.sub.5 is lower alkoxy.
- 9. The compound of claim 8 wherein said compound is 9-(4-methoxy-2,6-dimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid.
- 10. The compound of claim 8 wherein said compound is 9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid.
- 11. The compound of claim 1 wherein at least one of R.sub.4 and R.sub.5 is lower alkenyl.
- 12. The compound of claim 63 wherein said compound is 9-(4-methoxy-3-allyl-2,6-dimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid.
- 13. The compound of claim 1 wherein at least one of R.sub.3, R.sub.4 or R.sub.5 is nitro.
- 14. The compound of claim 13 wherein said compound is 9-(3-nitro-2,4,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid.
- 15. The compound of claim 1 wherein at least one of R.sub.3 or R.sub.5 is halogen.
- 16. The compound of claim 15 wherein said compound is 9-(3-chloro-2,4,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid.
- 17. The compound of claim 1 wherein at least one of R.sub.3, R.sub.4 or R.sub.5 is lower alkenyloxy.
- 18. The compound of claim 17 wherein said compound is 9-(4-allyloxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid.
CROSS REFERENCE TO RELATED APPLICATIONS
This application is a continuation-in-part application of prior application Ser. No. 601,148, filed Aug. 1, 1975 now abandoned, which in turn is a continuation-in-part application of application Ser. No. 454,007, filed Mar. 22, 1974 now abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
3781314 |
Bollag et al. |
Dec 1973 |
|
3845089 |
Henrick |
Oct 1974 |
|
Continuation in Parts (2)
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Number |
Date |
Country |
Parent |
601148 |
Aug 1975 |
|
Parent |
454007 |
Mar 1974 |
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